The Chinese pangolin(Manis pentadactyla,MP)has been extensively exploited and is now on the brink of extinction,but its population structure,evolutionary history,and adaptive potential are unclear.Here,we analyzed 94 ...The Chinese pangolin(Manis pentadactyla,MP)has been extensively exploited and is now on the brink of extinction,but its population structure,evolutionary history,and adaptive potential are unclear.Here,we analyzed 94 genomes from three subspecies of the Chinese pangolin and identified three distinct genetic clusters(MPA,MPB,and MPC),with MPB further divided into MPB1 and MPB2 subpopulations.The divergence of these populations was driven by past climate change.For MPB2 and MPC,recent human activities have caused dramatic population decline and small population size as well as increased inbreeding,but not decrease in genomic variation and increase in genetic load probably due to strong gene flow;therefore,it is crucial to strengthen in situ habitat management for these two populations.By contrast,although human activities have a milder impact on MPA,it is at high risk of extinction due to long-term contraction and isolation,and genetic rescue is urgently needed.MPB1 exhibited a relatively healthy population status and can potentially serve as a source population.Overall,our findings provide novel insights into the conservation of the Chinese pangolin and biogeography of the mammals of eastern Asia.展开更多
Since the introduction of the concept of frustrated Lewis pair by Stephan in 2006,the frustrated Lewis pair(FLP)chemistry has evolved into a rich and fruitful research area which is largely responsible for the renaiss...Since the introduction of the concept of frustrated Lewis pair by Stephan in 2006,the frustrated Lewis pair(FLP)chemistry has evolved into a rich and fruitful research area which is largely responsible for the renaissance of main group chemistry in recent years.Among many applications of FLP,design of catalytic systems based on the concept of FLP,pioneered by Stephan,Chen and others,provides a powerful arsenal that has been applied to organic synthesis and polymerization.This article will highlight key advances in the development of FLP related catalysis.展开更多
基金supported by the Major Program of the Natural Science Foundation of Jiangxi Province of China(20233ACB209001)Guangdong Basic and Applied Basic Research Foundation(2022A1515111016)+1 种基金Science and Technology Department of Guangdong Province(2021QN02H103)Natural Resources Affairs Management-Ecological Forestry Construction Special Project of Forestry Administration of Guangdong Province(SLYJ2023B4002,SLYJ2023B4003,SLYJ2023B4005)。
文摘The Chinese pangolin(Manis pentadactyla,MP)has been extensively exploited and is now on the brink of extinction,but its population structure,evolutionary history,and adaptive potential are unclear.Here,we analyzed 94 genomes from three subspecies of the Chinese pangolin and identified three distinct genetic clusters(MPA,MPB,and MPC),with MPB further divided into MPB1 and MPB2 subpopulations.The divergence of these populations was driven by past climate change.For MPB2 and MPC,recent human activities have caused dramatic population decline and small population size as well as increased inbreeding,but not decrease in genomic variation and increase in genetic load probably due to strong gene flow;therefore,it is crucial to strengthen in situ habitat management for these two populations.By contrast,although human activities have a milder impact on MPA,it is at high risk of extinction due to long-term contraction and isolation,and genetic rescue is urgently needed.MPB1 exhibited a relatively healthy population status and can potentially serve as a source population.Overall,our findings provide novel insights into the conservation of the Chinese pangolin and biogeography of the mammals of eastern Asia.
基金the National Natural Science Foundation of China(21672039,21871051,22071027)Shanghai Science and Technology Committee(19DZ2270100)is gratefully acknowledged.
文摘Since the introduction of the concept of frustrated Lewis pair by Stephan in 2006,the frustrated Lewis pair(FLP)chemistry has evolved into a rich and fruitful research area which is largely responsible for the renaissance of main group chemistry in recent years.Among many applications of FLP,design of catalytic systems based on the concept of FLP,pioneered by Stephan,Chen and others,provides a powerful arsenal that has been applied to organic synthesis and polymerization.This article will highlight key advances in the development of FLP related catalysis.
