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前白蛋白/纤维蛋白原比值与胃癌临床病理特征的关系 被引量:7
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作者 张俊斌 王浩浩 +4 位作者 王伟斌 王海勇 陆轶民 俞雄飞 滕理送 《世界华人消化杂志》 CAS 2019年第18期1133-1141,共9页
背景既往研究表明前白蛋白(prealbumin,PA)与纤维蛋白原(fibrinogen,Fib)可用于判断多种恶性肿瘤的临床病理特征及预后.因此本研究推测前白蛋白/纤维蛋白原比值(prealbumin-to-fibrinogen,PA/F)可预测胃癌(gastric cancer,GC)患者临床... 背景既往研究表明前白蛋白(prealbumin,PA)与纤维蛋白原(fibrinogen,Fib)可用于判断多种恶性肿瘤的临床病理特征及预后.因此本研究推测前白蛋白/纤维蛋白原比值(prealbumin-to-fibrinogen,PA/F)可预测胃癌(gastric cancer,GC)患者临床病理特征,术前辅助判断肿瘤进展程度.目的探讨术前PA与Fib比值PA/F和GC临床病理特征的关系.方法回顾性分析2017-01/2019-03浙江大学附属第一医院肿瘤外科收治的210例GC患者术前临床病理资料并分为低PA/F组和高PA/F组.比较两组临床资料及病理学特征的差异并分析PA/F值与其他预后相关免疫营养指标的相关性.结果PA/F值与年龄、肿瘤大小、分化程度、浸润深度、淋巴结转移、TNM分期和神经血管侵犯相关(P<0.05),低PA/F值组表现出患者年龄更大、肿瘤最大径更大、分化程度更差、浸润深度更深、TNM分期更晚和更易神经脉管侵犯(P<0.05).PA/F值与中性粒细胞与淋巴细胞比值(neutrophil-to-lymphocyte ratio,NLR)、血小板与淋巴细胞比值(platelet-to-lymphocyteratio,PLR)、C反应蛋白与白蛋白比值(C-reactiveprotein-to-albumin ratio,CAR)和系统性免疫炎症指数(systemic immune-inflammation index,SII)呈负相关性,与预后营养指数(prognostic nutritional index,PNI)呈正相关性.结论PA/F值可作为GC患者术前临床病理特征的判断指标,其值≤9.07提示肿瘤处于进展期,TNM分期相对较差,PA/F值与NLR、PLR、CAR、SII和PNI多种GC预后指数具有相关性. 展开更多
关键词 前白蛋白 纤维蛋白原 胃癌 临床病理特征
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Gastritis cystica profunda in a previously unoperated stomach:A case report 被引量:10
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作者 xiong-fei yu Li-Wen Guo +1 位作者 Shi-Tu Chen Li-Song Teng 《World Journal of Gastroenterology》 SCIE CAS 2015年第12期3759-3762,共4页
Gastritis cystica profunda is a relatively rare disease, usually observed at anastomotic sites in stomachs of patients that have undergone gastric procedures. We present the rare case of an elevated lesion in the ante... Gastritis cystica profunda is a relatively rare disease, usually observed at anastomotic sites in stomachs of patients that have undergone gastric procedures. We present the rare case of an elevated lesion in the anterior wall of the gastric antrum of a 43-year-old Chinese woman who had never undergone gastric surgery and had no gastrointestinal tract symptoms. Although the physical examination and laboratory data showed no abnormalities, endoscopic ultrasonography revealed an anechoic cystic structure. Abdominalcomputed tomography and magnetic resonance imaging showed the gastric wall of the greater curvature of the antrum was markedly and irregularly thickened, and mild to moderate enhancement was observed around the lesion with no enhancement in the central portion, suggestive of a gastrointestinal stromal tumor. The patient underwent a distal gastric resection of the 2.5 cm × 1.5 cm lesion. A postoperative pathologic examination showed dilated cystic glands in the muscularis mucosa and submucosal layers and erosion of the mucosal surface of the tumor, confirming the diagnosis of gastritis cystica profunda without malignancy. 展开更多
关键词 GASTRITIS cystica profunda Hyperplastic POLYP Stom
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Indocyanine green clearance in evaluating the recovery of liver reserve function after superselective transarterial chemoembolization 被引量:9
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作者 Xin Chen Hai-Bing Zhang +4 位作者 Zhong-Qi Li xiong-fei yu Mei-Fang Yang Hao-Hao Wang Li-Song Teng 《Hepatobiliary & Pancreatic Diseases International》 SCIE CAS 2013年第6期656-660,共5页
Transarterial chemoembolization(TACE)may ravage normal liver tissues apart from the neoplastic nodules which offset the anti-tumor effect.This study aimed to evaluate the recovery of liver reserve function(LRF)after T... Transarterial chemoembolization(TACE)may ravage normal liver tissues apart from the neoplastic nodules which offset the anti-tumor effect.This study aimed to evaluate the recovery of liver reserve function(LRF)after TACE by indocyanine green(ICG)clearance test and other routine liver function tests.Forty-six newly diagnosed HCC patients who had undergone TACE as the initial treatment from January 2011 to January 2012 were enrolled in this study.The effects of age,basic ICG clearance rate and interval time between two assessments on the recovery of LRF were analyzed.We found that ICG retention rate at the 15 minutes(ICGR15)was significantly increased after TACE(12.3±8.1%vs 16.8±12.1%,P【0.01)in all the 46 patients.In particular,the ICGR15 value was increased in older patients(age】55 years,20.3±12.5%vs 13.7±7.2%,P【0.01).The interval of ICG test also affected the ICGR15 value(≤47days,17.8±11.4%after vs 12.1±7.1%before TACE,P【0.01).Our data suggested that TACE decreased LRF,especially in older patients.ICG test was more sensitive to evaluate the recovery of LRF after TACE than the Child-Pugh grade and routine liver function tests. 展开更多
关键词 hepatocellular carcinoma transarterial chemoembolization liver reserve function indocyanine green clearance
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