PREFACE

This special issue of Acta Mathematica Scientia is dedicated to Professor Banghe Li on the occasion of his 80th birthday.Professor Banghe Li was born in Yueqing City,Zhejiang Province.He graduated from the University of Science and Technology of China in 1965 and has been working in the Chinese Academy of Sciences since then.He was elected as an Academician of the Chinese Academy of Sciences in 2001.

A red pomegranate fruit extract-based formula ameliorates anxiety/depression-like behaviors via enhancing serotonin (5-HT) synthesis in C57BL/6 male mice

This study investigated the anti-anxiety/anti-depression potential of a formula containing red pomegranate fruit extract(RPFE;40%,m/m),Lactobacillus rhamnosus(JB-1)(34%,m/m),magnesium gluconate(25%,m/m)and vanillin(1%,m/m).The RPFE formula(dose:2.0,1.5 or 1.0 mg/g·day)reversed behavioral dysfunctions and body weight gain induced by chronic restraint stress combined with corticosterone injection in C57BL/6 male mice.The RPFE formula exhibited the abilities to normalize the levels of serum infl ammatory cytokines(NF-κB,TNF-α,IL-6,IL-1βand IFN-γ)and malondialdehyde(MDA),and activities of superoxide dismutase(SOD),catalase(CAT)and nitric oxide synthase(NOS),as well as relieve the injury of hippocampal neurons.The serotonin(5-HT)levels in hippocampus were increasingly enhanced,which might be mediated by reducing the activity of indoleamine-2,3-dioxygenase(IDO)and increasing the activity of tryptophan hydroxylase(TPH).Thus,the neuroprotective and ameliorating effects on anxiety/depression-like behaviors resulting from the RPFE formula ingestion were possibly related to serotonergic activation,which might be mediated via anti-infl ammatory and anti-oxidant actions.

Preface

Editors-in-Chief： Gui-Qiang Chen, Banghe Li and Xiping Zhu This special issue of Acta Mathematica Scientia is dedicated to the memory of Professor Xiaqi Ding, a former Editor-in-Chief of this journal, on the occasion of his ninetieth anniversary.

Complications of Laparoscopic Choledochotomy and Lithotomy for Primary Suture

Objective:To explore the non-placement of“T”tube after laparoscopic choledochotomy.feasibility and complication analysis of primary suture bile duct.Methods:Retrospective analysis of January 2013~December 2016,Laparoscopic choledocholithotomy for primary bile duct suture in 87 cases,Combined with literature,the indications,methods and complications of the operation were summarized and analyzed.Results:There was no operative death in the whole group,Postoperative complications occurred in 5 cases(5.7%),1 case with jaundice,gradually subsided after 4 days of conservative treatment.Two cases had postoperative bile leakage,to prolong the drainage time of the peritoneal drainage tube and stop by itself.In 1 case,bile duct stenosis occurred.1 case of residual common bile duct stones.The average postoperative hospitalization was 9 days.Conclusion:Select the right case strictly,Patient and delicate operation,Laparoscopic choledochotomy is safe and feasible.

Analysis of 87 Cases of laparoscopic Choledochotomy with Primary Suture

To investigate the feasibility and clinical effect of laparoscopic choledochotomy for primary suture of bile duct.Methods:There were 190 cases of cholecystolithiasis with choledocholithiasis.They were randomly divided into endoscopic group and open group.In the endoscopic group,87 patients underwent laparoscopic choledocholithotomy and primary bile duct suture.A total of 103 patients in open group were treated with open bile duct incision and T tube drainage.The operative time,intraoperative blood loss,postoperative ventilation time,hospital stay and postoperative complications were compared between the two groups.Results:The length of hospital stay,the amount of bleeding during operation and the time of postoperative ventilation were less than those in open group.The operation time was longer than that in open group,P<0.01.There were 0 cases of postoperative incision infection,2 cases of bile leakage and 1 case of residual stone in endoscopic group.The incidence of complications was 5.7%.The open group was 5,3,3 and 10.7% respectively.Comparison of complications between the two groups,P<0.01.Conclusion:Select the right case strictly,Laparoscopic and choledochoscopy combined with cholecystolithiasis with choledocholithiasis is effective,safe and minimally invasive,short hospitalization time and less complications.