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基于加权TOPSIS法的氨甲环酸氯化钠注射液药物利用评价
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作者 李美娟 刘秀梅 +5 位作者 李雷 刘建萍 刘利勤 向倩 张进华 李青 《药物流行病学杂志》 CAS 2023年第12期1321-1330,共10页
目的建立氨甲环酸氯化钠注射液药物利用评价(DUE)标准,为临床合理用药提供依据。方法以药品说明书为基础,参照相关指南及文献,制定DUE标准细则,采用加权优劣解距离法(TOPSIS)对山西医科大学第一医院2022年2—8月出院病历进行合理性评价... 目的建立氨甲环酸氯化钠注射液药物利用评价(DUE)标准,为临床合理用药提供依据。方法以药品说明书为基础,参照相关指南及文献,制定DUE标准细则,采用加权优劣解距离法(TOPSIS)对山西医科大学第一医院2022年2—8月出院病历进行合理性评价。结果171份病历中,用药方案与最优方案接近程度(C_(i))≥0.8(合理)的有66例,占38.60%;C_(i)介于0.6~0.8(基本合理)的73例,占42.69%;C_(i)<0.6(不合理)的32例,占18.71%。不合理用药主要表现在不良反应监护、给药剂量、适应证等方面。结论采用加权TOPSIS法对氨甲环酸氯化钠注射液进行合理性评价,其评价结果更加直观、方便。 展开更多
关键词 氨甲环酸氯化钠注射液 加权优劣解距离法 药物利用评价
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年龄、体重指数与女性生育因素对乳腺密度的影响研究 被引量:4
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作者 冯娜娜 王庆海 +2 位作者 陈雯 刘秀梅 于代友 《中国现代医学杂志》 CAS 北大核心 2017年第28期51-55,共5页
目的探讨年龄、体重指数(BMI)与女性生育因素对乳腺密度的影响。方法对符合纳入标准且自愿接受全数字乳腺X射线检查的女性5 006例,依据第4版ACR BI-RADS分类系统对乳腺密度进行分型,分析年龄、BMI及女性生育因素与乳腺密度间的关系。结... 目的探讨年龄、体重指数(BMI)与女性生育因素对乳腺密度的影响。方法对符合纳入标准且自愿接受全数字乳腺X射线检查的女性5 006例,依据第4版ACR BI-RADS分类系统对乳腺密度进行分型,分析年龄、BMI及女性生育因素与乳腺密度间的关系。结果乳腺密度在不同年龄段之间比较,差异有统计学意义(P<0.05)。BMI、初潮年龄、持续时间、是否绝经、孕次数、母乳喂养时间及活产数在4个乳腺密度类型间差异均具有统计学意义(P<0.05),而月经周期差异无统计学意义(P>0.05)。对乳腺密度有影响的因素进行Logistic分析显示,只有年龄、BMI、是否绝经、活产数及母乳喂养时间进入方程,对乳腺密度类型有影响作用。结论年龄、BMI、是否绝经、活产数及母乳喂养时间对乳腺密度有不同程度影响。 展开更多
关键词 乳腺密度 年龄 体重指数 生育因素
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Foodborne Pathogens in Retail Oysters in South China
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作者 YAN CHEN xiu-mei liu +4 位作者 JI-WEN YAN XIU-GUI LI LING-LING MEI QUN-FEI MA YI MA 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2010年第1期32-36,共5页
Objective To investigate the occurrence of important foodbome pathogens in shellstock Pacific oysters in the food markets in South China. Methods From July 2007 to June 2008, retail oysters were collected in different... Objective To investigate the occurrence of important foodbome pathogens in shellstock Pacific oysters in the food markets in South China. Methods From July 2007 to June 2008, retail oysters were collected in different seasons from South China and analyzed for the prevalence and levels of Listeria monocytogenes, Vibrio vulnificus and Vibrio parahaemolyticus. Results None of L. monocytogenes could be detected in any of the 202 oyster samples tested, while E vulnificus and E parahaemolyticus could be detected in 67 (54.9%) and 109 (89.3%) of the 122 oyster samples analyzed, respectively, with an MPN (most probable number) value greater than or equal to 3. V. wdnificus and Eparahaemolyticus with a more than 102 MPN/g were found in 36 (29.5%) and 59 (48.4%) of the 122 oyster samples, respectively. The tdh and trh genes were detected in 4 (0.3%) and 8 (0.6%) of the 1 349 V. parahaemolyticus isolates, respectively. Of the 122 samples, 4 (3.3%) was positive for either tdh or trh. The levels of E vulnificus and total V. parahaemolyticus in oysters in South China varied in different seasons. Conclusion V. vulnificus and pathogenic V. parahaemolyticus are frequently found in oysters in south China, which may pose a potential threat to public health. Data presented here will be useful for the microbiological risk assessment in oysters in China. 展开更多
关键词 Listeria monocytogenes Vibrio vulnificus VIBRIOPARAHAEMOLYTICUS OYSTER Microbiological risk assessment
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COMONOMER SEQUENCE DISTRIBUTION IN METALLOCENE-BASED ETHYLENE/1-BUTENE (S-34) AND ETHYLENE/1-HEXENE (S-43) COPOLYMERS
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作者 Xiu-wen Han xiu-mei liu +4 位作者 Jin-kai Zhao Xin-he Bao Wei Chen Yi Deng Zhen-hua Jing Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China Research Institute of Petroleum Processing, Beijing 100083, China 《Chinese Journal of Polymer Science》 SCIE CAS CSCD 1999年第2期141-144,共4页
Metallocene based polyethylenes were prepared by SMOPEC's 'metallocene adduct' technology in a gas phase fluidized bed model reactor. The C-13-NMR spectra of ethylene/1-butene (S-34) and ethylene/1-hexene(... Metallocene based polyethylenes were prepared by SMOPEC's 'metallocene adduct' technology in a gas phase fluidized bed model reactor. The C-13-NMR spectra of ethylene/1-butene (S-34) and ethylene/1-hexene(S-43) copolymers were studied in a manner analogous to that established by Hsieh and Cheng. The comonomer sequence distributions of copolymer samples were obtained. The results show that these metallocene based copolymers contain a small amount of butene and hexene, and the EE and EEE sequences are dominant. 展开更多
关键词 METALLOCENE comonomer sequence distribution C-13-NMR
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Calf spleen extract alleviates cyclophosphamide-induced leucopenia in mice and inhibits the glycolysis of HL60 cells 被引量:2
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作者 Zhen-Yu Hu Xiao-Yan liu +2 位作者 xiu-mei liu Zhen-Jun Yang Yin-Ye Wang 《Journal of Chinese Pharmaceutical Sciences》 CAS 2011年第2期181-187,共7页
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