Environmental surveillance (ES) is a useful approach for monitoring circulating viruses, including polioviruses (PVs) and non-polio enteroviruses (NPEVs). In this study, the results of nine years of ES from 2013 to 20...Environmental surveillance (ES) is a useful approach for monitoring circulating viruses, including polioviruses (PVs) and non-polio enteroviruses (NPEVs). In this study, the results of nine years of ES from 2013 to 2021 at six sampling sites in three cities in Fujian Province, China, were summarized. It showed that the sewage samples contained abundant viruses, but the positive rate was affected by different sampling sites. From the 520 samples, 431 PVs, 1,713 NPEVs, and 281 human adenoviruses (HAdVs) were isolated. PV isolates had been markedly affected following the adjustment of the immunization strategy. All but one PV isolate were Sabin-like strains without wild PVs. One isolate was vaccine-derived PV type 3 with 10 variation points in theVP1 region. After May 2016, PV type 2 was no longer detected, and PV type 3 became a superior serotype. Of 1,713 NPEVs, 24 serotypes were identified, including echovirus11 (E11), E6, coxsackievirus B3 (CVB3), CVB5, E7, and E3 were the predominant serotypes (37.65%, 20.96%, 11.50%, 8.87%, 8.23%, and 7.06%, respectively). The temporal dynamic of the six common serotypes was inconsistent. E3 was frequently isolated, but the number of isolates was low, with no obvious peaks. E6, E7, and CVB3 exhibited periodic changes with a high peak every three to four years, and E11 only had one high peak lasting four years. Summer-fall peaks of the echoviruses and spring-winter peaks of CVB were observed in the monthly distribution of virus isolation. The infectious isolates of various serotypes of different species identified from the sewage samples showed that ES is an essential part of pathogen surveillance.展开更多
The Boltzmann equation with external potential force exists a unique equilibrium—local Maxwellian. The author constructs the nonlinear stability of the equilibrium when the initial datum is a small perturbation of th...The Boltzmann equation with external potential force exists a unique equilibrium—local Maxwellian. The author constructs the nonlinear stability of the equilibrium when the initial datum is a small perturbation of the local Maxwellian in the whole space R^3. Compared with the previous result [Ukai, S., Yang, T. and Zhao, H.-J.,Global solutions to the Boltzmann equation with external forces, Anal. Appl.(Singap.), 3,2005, 157–193], no smallness condition on the Sobolev norm H^1 of the potential is needed in our arguments. The proof is based on the entropy-energy inequality and the L^2-L~∞ estimates.展开更多
基金funded by Fujian Health System Youth Backbone Talents training project(2013-ZQN-ZD-10)leading(key)project of social development in Fujian Province(2017Y0011)National Key Research and Development Program of China(2021YFC2302003)。
文摘Environmental surveillance (ES) is a useful approach for monitoring circulating viruses, including polioviruses (PVs) and non-polio enteroviruses (NPEVs). In this study, the results of nine years of ES from 2013 to 2021 at six sampling sites in three cities in Fujian Province, China, were summarized. It showed that the sewage samples contained abundant viruses, but the positive rate was affected by different sampling sites. From the 520 samples, 431 PVs, 1,713 NPEVs, and 281 human adenoviruses (HAdVs) were isolated. PV isolates had been markedly affected following the adjustment of the immunization strategy. All but one PV isolate were Sabin-like strains without wild PVs. One isolate was vaccine-derived PV type 3 with 10 variation points in theVP1 region. After May 2016, PV type 2 was no longer detected, and PV type 3 became a superior serotype. Of 1,713 NPEVs, 24 serotypes were identified, including echovirus11 (E11), E6, coxsackievirus B3 (CVB3), CVB5, E7, and E3 were the predominant serotypes (37.65%, 20.96%, 11.50%, 8.87%, 8.23%, and 7.06%, respectively). The temporal dynamic of the six common serotypes was inconsistent. E3 was frequently isolated, but the number of isolates was low, with no obvious peaks. E6, E7, and CVB3 exhibited periodic changes with a high peak every three to four years, and E11 only had one high peak lasting four years. Summer-fall peaks of the echoviruses and spring-winter peaks of CVB were observed in the monthly distribution of virus isolation. The infectious isolates of various serotypes of different species identified from the sewage samples showed that ES is an essential part of pathogen surveillance.
基金supported by the Fundamental Research Funds for the Central Universities(No.NS2012122)
文摘The Boltzmann equation with external potential force exists a unique equilibrium—local Maxwellian. The author constructs the nonlinear stability of the equilibrium when the initial datum is a small perturbation of the local Maxwellian in the whole space R^3. Compared with the previous result [Ukai, S., Yang, T. and Zhao, H.-J.,Global solutions to the Boltzmann equation with external forces, Anal. Appl.(Singap.), 3,2005, 157–193], no smallness condition on the Sobolev norm H^1 of the potential is needed in our arguments. The proof is based on the entropy-energy inequality and the L^2-L~∞ estimates.
