Recent studies indicated that vitamin A(VA)might be involved in the pathology of type 2 diabetes mellitus(T2DM).This cross-sectional study was conducted to explore the association between circulating VA level and T2DM...Recent studies indicated that vitamin A(VA)might be involved in the pathology of type 2 diabetes mellitus(T2DM).This cross-sectional study was conducted to explore the association between circulating VA level and T2DM.A total of 1818 subjects aged 50 years old and above were recruited from the community.Binomial logistic regression and restricted cubic spline(RCS)were applied to analyze the association of plasma VA level with the risk of T2DM.Serum VA and lipid-adjusted VA levels of T2DM patients were significantly higher than that of non-T2DM subjects(P<0.05).The ratios of plasma VA/total cholesterol(TC),VA/high-density lipoprotein cholesterol(HDL-c)and VA/low-density lipoprotein cholesterol(LDL-c)were positively associated with the risk of T2DM in the aging population(P<0.05).Compared with the Q1 level,subjects with Q2 to Q3 levels of plasma VA/triglyceride(TG)have decreased risk of T2DM(odds ratio(OR)Q2=0.68,P_(Q2)=0.021;ORQ3=0.59,P_(Q3)<0.01).Our results indicated that the imbalance of circulating lipids and VA might affect the relationship between VA and T2DM.The middle and aging subjects with higher ratios of plasma VA/TC,VA/HDL-c,and VA/LDL-c displayed increased risk for T2DM,but the moderate ratio of VA/TG might protect against risk of T2DM.展开更多
In gas insulation switch(GIS)substation,secondary devices such as linemonitoring devices are placed in the switching field,and these electronic devices are vulnerable to transient electromagnetic interference caused b...In gas insulation switch(GIS)substation,secondary devices such as linemonitoring devices are placed in the switching field,and these electronic devices are vulnerable to transient electromagnetic interference caused by switching operation.In order to facilitate the measurement and research of electromagnetic disturbance data under different working conditions,a simulation test device is developed in this paper,which can be used to simulate electromagnetic disturbance of GIS substation sensor and secondary device port under switch operation.A four-channel parallel gas switch was designed,and the main characteristic parameters of electromagnetic disturbance generated by the simulation device were measured by using high-frequency pulse power supply as the excitation source.The comparison between the measured waveform and the measured disturbance characteristic parameters of GIS substation shows that it is in good agreement with the measured waveform characteristics,conforms to the basic characteristics of damped oscillation wave,and can be used in the secondary equipment port disturbance voltage coupling characteristics,protection measures evaluation and assessment method research.展开更多
基金funded by the National Natural Science Foundation of China(8217350881973027)Beijing Highlevel Public Health Technical Personnel Training Program(No.2022-3-032)。
文摘Recent studies indicated that vitamin A(VA)might be involved in the pathology of type 2 diabetes mellitus(T2DM).This cross-sectional study was conducted to explore the association between circulating VA level and T2DM.A total of 1818 subjects aged 50 years old and above were recruited from the community.Binomial logistic regression and restricted cubic spline(RCS)were applied to analyze the association of plasma VA level with the risk of T2DM.Serum VA and lipid-adjusted VA levels of T2DM patients were significantly higher than that of non-T2DM subjects(P<0.05).The ratios of plasma VA/total cholesterol(TC),VA/high-density lipoprotein cholesterol(HDL-c)and VA/low-density lipoprotein cholesterol(LDL-c)were positively associated with the risk of T2DM in the aging population(P<0.05).Compared with the Q1 level,subjects with Q2 to Q3 levels of plasma VA/triglyceride(TG)have decreased risk of T2DM(odds ratio(OR)Q2=0.68,P_(Q2)=0.021;ORQ3=0.59,P_(Q3)<0.01).Our results indicated that the imbalance of circulating lipids and VA might affect the relationship between VA and T2DM.The middle and aging subjects with higher ratios of plasma VA/TC,VA/HDL-c,and VA/LDL-c displayed increased risk for T2DM,but the moderate ratio of VA/TG might protect against risk of T2DM.
基金Science and Technology Project of State Grid Corporation of China(Project No.5226SX18000F)Science and Technology Project of State Grid Shaanxi Electric Power Company(Project No.5226KY18002M).
文摘In gas insulation switch(GIS)substation,secondary devices such as linemonitoring devices are placed in the switching field,and these electronic devices are vulnerable to transient electromagnetic interference caused by switching operation.In order to facilitate the measurement and research of electromagnetic disturbance data under different working conditions,a simulation test device is developed in this paper,which can be used to simulate electromagnetic disturbance of GIS substation sensor and secondary device port under switch operation.A four-channel parallel gas switch was designed,and the main characteristic parameters of electromagnetic disturbance generated by the simulation device were measured by using high-frequency pulse power supply as the excitation source.The comparison between the measured waveform and the measured disturbance characteristic parameters of GIS substation shows that it is in good agreement with the measured waveform characteristics,conforms to the basic characteristics of damped oscillation wave,and can be used in the secondary equipment port disturbance voltage coupling characteristics,protection measures evaluation and assessment method research.