目的:探讨血清血管生成素样蛋白-3(angiopoietin-like protein 3,ANGPTL3)水平与新疆哈萨克族人群急性冠脉综合征(acute coronary syndrome,ACS)的相关性。方法:选择已被明确诊断为ACS且经冠状动脉造影检查的新疆哈萨克族患者为研究对象...目的:探讨血清血管生成素样蛋白-3(angiopoietin-like protein 3,ANGPTL3)水平与新疆哈萨克族人群急性冠脉综合征(acute coronary syndrome,ACS)的相关性。方法:选择已被明确诊断为ACS且经冠状动脉造影检查的新疆哈萨克族患者为研究对象,依据Gensini积分将研究对象分为病例组和对照组。结果:与对照组患者相比,病例组患者的空腹血糖水平、空腹胰岛素水平、胰岛素抵抗指数、胰岛素分泌指数和高密度脂蛋白水平没有显著差异,但体质指数和血清ANGPTL3、总胆固醇、三酰甘油、极低密度脂蛋白水平显著更高。病例组患者的Gensini积分与体质指数和ANGPTL3、总胆固醇、极低密度脂蛋白水平均正相关,回归分析显示体质指数为ANGPTL3水平的影响因素。结论:血清ANGPTL3水平增高可能与新疆哈萨克族人群ACS的发生、发展相关,而体质指数是哈萨克族ACS患者ANGPTL3水平的影响因素。展开更多
OBJECTIVE:To evaluate the effectiveness of a combined Traditional Chinese Medicine(TCM) therapy versus conventional treatment on adolescent idiopathic scoliosis.METHODS:One hundred twenty outpatients with mild and mod...OBJECTIVE:To evaluate the effectiveness of a combined Traditional Chinese Medicine(TCM) therapy versus conventional treatment on adolescent idiopathic scoliosis.METHODS:One hundred twenty outpatients with mild and moderate adolescent idiopathic scoliosis were randomly divided into a TCM group(TCMG)and a brace group(CG).TCMG patients underwent Daoyin,Tuina,and acupotomology therapies.CG patients were treated with a Milwaukee brace.Each patient's Cobb angle was measured after 12 and 24 months of treatment,and pulmonary function was determined after 12 months of treatment.Average electromyogram(AEMG) ratio of the surface electromyogram was measured after 6 and 12 months of treatment and followed-up after 18 and 24 months.RESULTS:The Cobb angle significantly decreased in both groups after 12 months of treatment compared with before treatment(P< 0.05).The percentages of original Cobb angle in TCMG and CG were51.4%and 47.8%(P > 0.05) after 12 months and62.5%and 34.7%(P < 0.05) after 24 months,respectively.Pulmonary function significantly improved after 12 months in TCMG(P < 0.05) but significantly decreased in CG(P < 0.05).The AEMG ratio was significantly lower(P < 0.01) and tended to remain at1 after stopping treatment in TCMG,but increased in CG(P<0.05).CONCLUSION:TCM combined therapy can prevent the progression of scoliosis.The AEMG ratio is a promising index that could replace radiography in the evaluation of treatment effect and progression in scoliosis.展开更多
文摘目的:探讨血清血管生成素样蛋白-3(angiopoietin-like protein 3,ANGPTL3)水平与新疆哈萨克族人群急性冠脉综合征(acute coronary syndrome,ACS)的相关性。方法:选择已被明确诊断为ACS且经冠状动脉造影检查的新疆哈萨克族患者为研究对象,依据Gensini积分将研究对象分为病例组和对照组。结果:与对照组患者相比,病例组患者的空腹血糖水平、空腹胰岛素水平、胰岛素抵抗指数、胰岛素分泌指数和高密度脂蛋白水平没有显著差异,但体质指数和血清ANGPTL3、总胆固醇、三酰甘油、极低密度脂蛋白水平显著更高。病例组患者的Gensini积分与体质指数和ANGPTL3、总胆固醇、极低密度脂蛋白水平均正相关,回归分析显示体质指数为ANGPTL3水平的影响因素。结论:血清ANGPTL3水平增高可能与新疆哈萨克族人群ACS的发生、发展相关,而体质指数是哈萨克族ACS患者ANGPTL3水平的影响因素。
基金Supported by Outstanding Youth Fund of the Administration of Traditional Chinese Medicine of Zhejiang Province,China(No.2012ZQ011)
文摘OBJECTIVE:To evaluate the effectiveness of a combined Traditional Chinese Medicine(TCM) therapy versus conventional treatment on adolescent idiopathic scoliosis.METHODS:One hundred twenty outpatients with mild and moderate adolescent idiopathic scoliosis were randomly divided into a TCM group(TCMG)and a brace group(CG).TCMG patients underwent Daoyin,Tuina,and acupotomology therapies.CG patients were treated with a Milwaukee brace.Each patient's Cobb angle was measured after 12 and 24 months of treatment,and pulmonary function was determined after 12 months of treatment.Average electromyogram(AEMG) ratio of the surface electromyogram was measured after 6 and 12 months of treatment and followed-up after 18 and 24 months.RESULTS:The Cobb angle significantly decreased in both groups after 12 months of treatment compared with before treatment(P< 0.05).The percentages of original Cobb angle in TCMG and CG were51.4%and 47.8%(P > 0.05) after 12 months and62.5%and 34.7%(P < 0.05) after 24 months,respectively.Pulmonary function significantly improved after 12 months in TCMG(P < 0.05) but significantly decreased in CG(P < 0.05).The AEMG ratio was significantly lower(P < 0.01) and tended to remain at1 after stopping treatment in TCMG,but increased in CG(P<0.05).CONCLUSION:TCM combined therapy can prevent the progression of scoliosis.The AEMG ratio is a promising index that could replace radiography in the evaluation of treatment effect and progression in scoliosis.
