目的分析多发性硬化康复相关研究的热点和未来发展趋势。方法系统检索中国知网、维普网、万方数据知识服务平台、Web of Science核心合集数据库中关于多发性硬化康复的研究,检索时间为建库至2024年3月。利用CiteSpace 6.1.R6软件对发文...目的分析多发性硬化康复相关研究的热点和未来发展趋势。方法系统检索中国知网、维普网、万方数据知识服务平台、Web of Science核心合集数据库中关于多发性硬化康复的研究,检索时间为建库至2024年3月。利用CiteSpace 6.1.R6软件对发文量,作者,国家,机构,关键词共现、聚类和突现进行比较分析。结果共纳入中文文献105篇,英文文献2240篇,发文量总体呈上升趋势。中文文献未发现具有显著中心性的作者,机构间合作相对有限;英文文献发文量最多的作者是Motl RW(119篇)。发文量最高的国家是美国(646篇),中心性为0.31。中文文献的研究机构构建的网络结构较为稀疏,未见具有显著中心性的机构;英文文献发文量最多的机构是伊利诺伊大学(108篇)。中文文献的热点关键词是“吞咽障碍”“缓解期”“神经康复”,发现7个关键词聚类,突现强度最高的关键词为“护理”;英文文献的热点关键词是“quality of life”“people”“disability”,发现7个关键词聚类,突现强度最高的关键词为“disability”。结论近年来,多发性硬化的康复逐渐受到关注。然而,尽管国内在该领域已取得一定成果,但与国际发展水平相比,仍存在一定差距,更多多发性硬化相关的研究应该被开展,以期为患者的临床治疗提供参考。展开更多
背景:随着国内外多个细胞治疗产品获得临床试验批准,细胞治疗例如干细胞治疗、肿瘤过继免疫疗法得到广泛关注。体内细胞实时观察与成像可以直观显示细胞的分布,追踪细胞的活动,监测细胞的活性,观察细胞的迁移和生长。目前的许多成像技...背景:随着国内外多个细胞治疗产品获得临床试验批准,细胞治疗例如干细胞治疗、肿瘤过继免疫疗法得到广泛关注。体内细胞实时观察与成像可以直观显示细胞的分布,追踪细胞的活动,监测细胞的活性,观察细胞的迁移和生长。目前的许多成像技术可以使体内细胞可视化,例如超声、光学、磁共振成像以及核成像技术,这些方法均需对应不同的标记和检测策略,每种策略都有其固有的优点和缺点。目的:结合最新的研究动态,将对不同细胞追踪方法的原理、发展和这些方法在动物和人类中应用的最新进展进行综述。方法:第一作者以“cell tracking,in vivo cell tracking,PET imaging,MRI,optical imaging”为关键词在PubMed、Google Scholar、Web of Science、中国知网等数据库进行检索,重点关注过去5-10年的相关文章。文章内容主要描述不同细胞追踪方法的原理以及在动物模型和临床患者体内的细胞追踪应用。结果与结论:在过去的二十几年中,细胞追踪已经发展成为一个多方面的学科,不仅在动物模型中建立了多种稳健的方法,并且在人类的一些研究中证明了临床转化的可行性。尤其是以PET、MRI成像技术为代表的无创检测,新型对比剂的研发,为细胞治疗在临床与科研的应用提供了强有力的支持。展开更多
The cross bar H mode (CH) cavity is suitable to accelerate the low energy and medium energy proton. Theoperating mode in the CH cavity is H210. Compared with other low-beta superconducting cavities, the CH cavitywith ...The cross bar H mode (CH) cavity is suitable to accelerate the low energy and medium energy proton. Theoperating mode in the CH cavity is H210. Compared with other low-beta superconducting cavities, the CH cavitywith multi-cell structure has high real acceleration gradient. In superconducting CH cavity, the cross bar is helpfulto rigidize the cavity mechanically. Since the year of 2011, IMP have involved into the research of superconductingCH cavity for the ADS project[1]. There are three CH cavity have been fabricated, one copper model CH cavityand two niobium superconducting CH cavity[2].展开更多
The copper model CH cavity was designed and fabricated at IMP for Injector II of CIADS project operating atfrequency 162.5 MHz, =0.065[1]. To research the electromagnetic mode evaluated by the electric field distribut...The copper model CH cavity was designed and fabricated at IMP for Injector II of CIADS project operating atfrequency 162.5 MHz, =0.065[1]. To research the electromagnetic mode evaluated by the electric field distributionand the tuning properties of the CH cavity the bead-pull and tuning test device was set up. It included two parts,the beadpull mode and the tuning test mode. A brief description of the equipment design is shown in Fig.展开更多
O-line high-power tests of the power couplers for cavities prior to their on-line operations are of importance for ensuring their operating reliability and stability.To test the couplers using a limited power supply e...O-line high-power tests of the power couplers for cavities prior to their on-line operations are of importance for ensuring their operating reliability and stability.To test the couplers using a limited power supply effectively,a standing wave(SW)resonant-ring test system with two power input ports has been developed at the Radio Frequency Cavity Group.The schematic view of the new test system is shown in Fig.1.展开更多
In 2022,the SRF team completed the production delivery of 21 superconducting cavities for the China initia-tive Accelerator Driven Sub-critical System(CiADS),High Intensity heavy-ion Accelerator Facility(HIAF)and Nucl...In 2022,the SRF team completed the production delivery of 21 superconducting cavities for the China initia-tive Accelerator Driven Sub-critical System(CiADS),High Intensity heavy-ion Accelerator Facility(HIAF)and Nuclotron-based Ion Collider facility(NICA).And 12 cavities for researching and development have been delivered too.21 sets of power couplers for the SRF cavities have been nished too,and the RF condition is carrying on.9 sets of new designed frequency tuners with driver pressure by helium gas have been completed.展开更多
文摘目的分析多发性硬化康复相关研究的热点和未来发展趋势。方法系统检索中国知网、维普网、万方数据知识服务平台、Web of Science核心合集数据库中关于多发性硬化康复的研究,检索时间为建库至2024年3月。利用CiteSpace 6.1.R6软件对发文量,作者,国家,机构,关键词共现、聚类和突现进行比较分析。结果共纳入中文文献105篇,英文文献2240篇,发文量总体呈上升趋势。中文文献未发现具有显著中心性的作者,机构间合作相对有限;英文文献发文量最多的作者是Motl RW(119篇)。发文量最高的国家是美国(646篇),中心性为0.31。中文文献的研究机构构建的网络结构较为稀疏,未见具有显著中心性的机构;英文文献发文量最多的机构是伊利诺伊大学(108篇)。中文文献的热点关键词是“吞咽障碍”“缓解期”“神经康复”,发现7个关键词聚类,突现强度最高的关键词为“护理”;英文文献的热点关键词是“quality of life”“people”“disability”,发现7个关键词聚类,突现强度最高的关键词为“disability”。结论近年来,多发性硬化的康复逐渐受到关注。然而,尽管国内在该领域已取得一定成果,但与国际发展水平相比,仍存在一定差距,更多多发性硬化相关的研究应该被开展,以期为患者的临床治疗提供参考。
文摘背景:随着国内外多个细胞治疗产品获得临床试验批准,细胞治疗例如干细胞治疗、肿瘤过继免疫疗法得到广泛关注。体内细胞实时观察与成像可以直观显示细胞的分布,追踪细胞的活动,监测细胞的活性,观察细胞的迁移和生长。目前的许多成像技术可以使体内细胞可视化,例如超声、光学、磁共振成像以及核成像技术,这些方法均需对应不同的标记和检测策略,每种策略都有其固有的优点和缺点。目的:结合最新的研究动态,将对不同细胞追踪方法的原理、发展和这些方法在动物和人类中应用的最新进展进行综述。方法:第一作者以“cell tracking,in vivo cell tracking,PET imaging,MRI,optical imaging”为关键词在PubMed、Google Scholar、Web of Science、中国知网等数据库进行检索,重点关注过去5-10年的相关文章。文章内容主要描述不同细胞追踪方法的原理以及在动物模型和临床患者体内的细胞追踪应用。结果与结论:在过去的二十几年中,细胞追踪已经发展成为一个多方面的学科,不仅在动物模型中建立了多种稳健的方法,并且在人类的一些研究中证明了临床转化的可行性。尤其是以PET、MRI成像技术为代表的无创检测,新型对比剂的研发,为细胞治疗在临床与科研的应用提供了强有力的支持。
基金National Natural Science Foundation of China (91026001)
文摘The cross bar H mode (CH) cavity is suitable to accelerate the low energy and medium energy proton. Theoperating mode in the CH cavity is H210. Compared with other low-beta superconducting cavities, the CH cavitywith multi-cell structure has high real acceleration gradient. In superconducting CH cavity, the cross bar is helpfulto rigidize the cavity mechanically. Since the year of 2011, IMP have involved into the research of superconductingCH cavity for the ADS project[1]. There are three CH cavity have been fabricated, one copper model CH cavityand two niobium superconducting CH cavity[2].
文摘The copper model CH cavity was designed and fabricated at IMP for Injector II of CIADS project operating atfrequency 162.5 MHz, =0.065[1]. To research the electromagnetic mode evaluated by the electric field distributionand the tuning properties of the CH cavity the bead-pull and tuning test device was set up. It included two parts,the beadpull mode and the tuning test mode. A brief description of the equipment design is shown in Fig.
文摘O-line high-power tests of the power couplers for cavities prior to their on-line operations are of importance for ensuring their operating reliability and stability.To test the couplers using a limited power supply effectively,a standing wave(SW)resonant-ring test system with two power input ports has been developed at the Radio Frequency Cavity Group.The schematic view of the new test system is shown in Fig.1.
文摘In 2022,the SRF team completed the production delivery of 21 superconducting cavities for the China initia-tive Accelerator Driven Sub-critical System(CiADS),High Intensity heavy-ion Accelerator Facility(HIAF)and Nuclotron-based Ion Collider facility(NICA).And 12 cavities for researching and development have been delivered too.21 sets of power couplers for the SRF cavities have been nished too,and the RF condition is carrying on.9 sets of new designed frequency tuners with driver pressure by helium gas have been completed.
