objective:The effects of different chitosan on preventing traumatic peritoneal adhesion in rats was studied in this paper. METHODS: 96 SD rats with injured vermiform process were randomly divided into 4 groups as foll...objective:The effects of different chitosan on preventing traumatic peritoneal adhesion in rats was studied in this paper. METHODS: 96 SD rats with injured vermiform process were randomly divided into 4 groups as follows: group A without any treatment as control, group B treated with chitosan gel, group C treated with pure chitosan film and group D treated with chiston film containing 50% gelatin. 2 and 4 weeks after surgery, 12 rats in each group were respectively belly opened to observe chitosan degradation and evaluate peritoneal adhesion, and the adhesive vermiform processes tissues were histopathologically observed. RESULTS: 1.Degradation in the group D was faster than that in the group C but slower than that in the group B. 2. 2 weeks after surgery the adhesion in the group B was milder than that in the control group(goup A) (P<0.05), but that in the group C and D (both P<0.05) were more severe than that in the control group . 3. 4 weeks after surgery , the adhesion in the group B was milder than that in the control group (P<0.05), but that in the group C and D (both P<0.05) were more severe than that in the control group , whereas, there was no significant difference between adhesion in the group C and group D (P>0.05). 4.Histopathological examinaiton indicated that: 2 weeks after surgery ,inflammatory cell infiltration and fibroplastic proliferation dominated in local lesion and the response was most severe on the serous coat, furthermore, the response in the control group was more severe than that in the group B, but milder than that in the group C and D; 4 weeks after surgery, fibroplastic proliferation dominated in local lesion in each group , moreover, the response in the control group was more severe than that in the group B but milder than that in the group C and D. What’s more, integrated fibrous membrane formed around implanted materials in the group C and D, and the fibrous membranes were thinner in the group C than that in the group D. CONCLUSION: 1.Chitosan gel has perfect effect in protecting traumatic peritoneal adhesion in rats. 2.Pure chitosan film could exacerbate peritoneal adhesion and chitosan containing gelatin could exacerbate peritoneal adhesion further.展开更多
Objective:To observe the clinical efficacy of acupuncture plus acupoint sticking for bronchial asthma in remissive state.Methods:A total of 210 cases with asthma at remissive state were randomly allocated into an acup...Objective:To observe the clinical efficacy of acupuncture plus acupoint sticking for bronchial asthma in remissive state.Methods:A total of 210 cases with asthma at remissive state were randomly allocated into an acupuncture group of 100 cases and a comprehensive therapy group of 110 cases.Cases in the acupuncture group were treated with acupuncture alone,and cases in the comprehensive therapy group were treated with acupuncture plus acupoint sticking therapy.Then the therapeutic efficacies were compared using observation indexes including wheezing,cough and coughing up phlegm,peak expiratory flow(PEF)and forced expiratory volume in one second(FEV1).In addition,the overall therapeutic efficacies were also analyzed on different traditional Chinese medicine(TCM)patterns.Results:The comprehensive therapy obtained better effects than acupuncture alone in alleviating cough and coughing up phlegm and improving PEF and FEV1;the overall efficacies on asthma due to lung-qi deficiency and spleen-qi deficiency were better than those on asthma due to kidney-qi deficiency.Conclusion:Acupuncture plus acupoint sticking is a convenient and effective therapy for asthma at remissive state and therefore worthy of being popularized.展开更多
文摘objective:The effects of different chitosan on preventing traumatic peritoneal adhesion in rats was studied in this paper. METHODS: 96 SD rats with injured vermiform process were randomly divided into 4 groups as follows: group A without any treatment as control, group B treated with chitosan gel, group C treated with pure chitosan film and group D treated with chiston film containing 50% gelatin. 2 and 4 weeks after surgery, 12 rats in each group were respectively belly opened to observe chitosan degradation and evaluate peritoneal adhesion, and the adhesive vermiform processes tissues were histopathologically observed. RESULTS: 1.Degradation in the group D was faster than that in the group C but slower than that in the group B. 2. 2 weeks after surgery the adhesion in the group B was milder than that in the control group(goup A) (P<0.05), but that in the group C and D (both P<0.05) were more severe than that in the control group . 3. 4 weeks after surgery , the adhesion in the group B was milder than that in the control group (P<0.05), but that in the group C and D (both P<0.05) were more severe than that in the control group , whereas, there was no significant difference between adhesion in the group C and group D (P>0.05). 4.Histopathological examinaiton indicated that: 2 weeks after surgery ,inflammatory cell infiltration and fibroplastic proliferation dominated in local lesion and the response was most severe on the serous coat, furthermore, the response in the control group was more severe than that in the group B, but milder than that in the group C and D; 4 weeks after surgery, fibroplastic proliferation dominated in local lesion in each group , moreover, the response in the control group was more severe than that in the group B but milder than that in the group C and D. What’s more, integrated fibrous membrane formed around implanted materials in the group C and D, and the fibrous membranes were thinner in the group C than that in the group D. CONCLUSION: 1.Chitosan gel has perfect effect in protecting traumatic peritoneal adhesion in rats. 2.Pure chitosan film could exacerbate peritoneal adhesion and chitosan containing gelatin could exacerbate peritoneal adhesion further.
基金supported by the Third Shanghai Municipal Priority Subspecialty(Special Diseases)Construction ProjectShanghai TCM Groups and Special Technique Support Project
文摘Objective:To observe the clinical efficacy of acupuncture plus acupoint sticking for bronchial asthma in remissive state.Methods:A total of 210 cases with asthma at remissive state were randomly allocated into an acupuncture group of 100 cases and a comprehensive therapy group of 110 cases.Cases in the acupuncture group were treated with acupuncture alone,and cases in the comprehensive therapy group were treated with acupuncture plus acupoint sticking therapy.Then the therapeutic efficacies were compared using observation indexes including wheezing,cough and coughing up phlegm,peak expiratory flow(PEF)and forced expiratory volume in one second(FEV1).In addition,the overall therapeutic efficacies were also analyzed on different traditional Chinese medicine(TCM)patterns.Results:The comprehensive therapy obtained better effects than acupuncture alone in alleviating cough and coughing up phlegm and improving PEF and FEV1;the overall efficacies on asthma due to lung-qi deficiency and spleen-qi deficiency were better than those on asthma due to kidney-qi deficiency.Conclusion:Acupuncture plus acupoint sticking is a convenient and effective therapy for asthma at remissive state and therefore worthy of being popularized.
