目的探讨双水平气道正压通气(BiPAP)无创呼吸机通气联合肺康复治疗在老年护理机构慢性阻塞性肺疾病(COPD)稳定期合并高碳酸血症患者中的应用效果。方法选取2018年2月—2019年2月收治的47例老年COPD稳定期合并高碳酸血症接受肺康复的患者...目的探讨双水平气道正压通气(BiPAP)无创呼吸机通气联合肺康复治疗在老年护理机构慢性阻塞性肺疾病(COPD)稳定期合并高碳酸血症患者中的应用效果。方法选取2018年2月—2019年2月收治的47例老年COPD稳定期合并高碳酸血症接受肺康复的患者,采用随机数字表法随机分成研究组(n=23)和对照组(n=24)。对照组予低流量鼻导管吸氧、化痰、扩张支气管、布地奈德福莫特罗吸入剂、营养治疗、有氧训练、阻抗训练以及心理支持等治疗措施;研究组在对照组的治疗基础上联合给予无创BiPAP治疗。比较2组患者的临床疗效、血气指标、慢性阻塞性肺疾病评估测试(CAT)、6min步行试验(6MWT)、肺功能及并发症发生情况。结果治疗4周,研究组二氧化碳分压和6MWT的改善程度优于对照组,差异有统计学意义(P<0.05);研究组FEV1及FEV1占预计值百分比有所提升,且研究组改善情况优于对照组(P<0.05)。研究组临床疗效总有效率高于对照组(91.3% vs 62.5%,P=0.049),继发肺部感染的发生率低于对照组(26.1% vs 62.5%,P=0.037)。结论BiPAP无创呼吸机通气联合肺康复治疗在合并高碳酸血症的老年COPD稳定期患者中疗效显著,能有效改善患者的临床症状、血气指标及肺功能,降低二氧化碳潴留及呼吸性酸中毒,减少肺部感染的发生率。展开更多
OBJECTIVE: To observe the clinical effect of oral traditional Chinese medicine granules combined with health education to regulate phlegm constitution and treat simple obesity. METHODS: According to the method of cons...OBJECTIVE: To observe the clinical effect of oral traditional Chinese medicine granules combined with health education to regulate phlegm constitution and treat simple obesity. METHODS: According to the method of constitution evaluation in TCM Constitution Classification and Evaluation(Chinese Association of Chinese Medicine), the TCM classification of Chinese medicine was performed on patients who came to the outpatient department of the Traditional Chinese Medicine Hospital of Pinggu District of Beijing and met the diagnostic criteria of simple obesity. One hundred patients with phlegm constitution were selected and those in accordance with the standards, were randomly divided into group with oral TCM granules combined with health education(refer to as treatment group) and health education group(refer to as control group) according to 1:1 ratio. The control group was given health education including diet and exercise instruction. Treatment group:(1) Health education includes diet and exercise instruction.(2) Oral Chinese medicine granules: ingredients: atractylodes rhizome 15g, raw barley 30g, Folium Nelumbinis 10g, Chinese hawthorn fruit 10g, Chinese waxgourd peel 15g, milk-vetch root;15g, kudzuvine root 15g, danshen root10g, 2 times/d. The two groups were intervened for 12 weeks each time, and obesity evaluation indicators such as body weight, body fat, waist circumference, hip circumference, weight index, and score table of TCM constitutional were observed before and after the intervention. Statistical software was used for statistical analysis. RESULTS: The total curative effect of the treatment group was better than that of the control group(P<0.001). The weight index, body weight, waist and hip circumference decreased significantly after treatment(P <0.01). Compared with the two groups, the treatment group is better than the control group in terms of dampness constitution improvement, weight and fat losing and waist and hip circumference reducing.(P<0.01). CONCLUSION: Oral Chinese medicine granules Jiangzhuo Fang(combined with health education) and simple health education can improve phlegm constitution, and improve the body weight, body fat percentage and other indicators of the patients, but oral granules combined with health education to improve the physical fitness of phlegm is better than simple health education. The thoughts and methods of Chinese medicine granules combined with health education to regulate phlegm constitution is effective for weight losing and is worthy of further research and promotion.展开更多
OBJECTIVE:To evaluate the effectiveness of traditional Chinese herbal Xinglouchengqi(XLCQ)decoction for the treatment of constipation in acute ischemic stroke patients,and figure out the role that bowel movements play...OBJECTIVE:To evaluate the effectiveness of traditional Chinese herbal Xinglouchengqi(XLCQ)decoction for the treatment of constipation in acute ischemic stroke patients,and figure out the role that bowel movements play in the treatment of acute ischemic stroke.METHODS:A total of 317 eligible patients were recruited and randomized to the XLCQ group(211 patients)or the control group(106 patients).In addition to conventional standard medical care and rehabilitation,participants in the XLCQ group received XLCQ decoction,while the control group received clysis therapy using glycerin enemas or lactulose oral solution.Both groups were given treatment for 3 to 6 d,during which they received daily visits to record defecation features and accompanying symptoms.Neurological assessments using the National Institutes of Health Stroke Scale(NIHSS)were conducted before and 1 month after treatment.RESULTS:Patients in the XLCQ group had lower aggregate constipation scores compared with the control group on days 3 and 5(P<0.05).Spontaneous bowel movements tended to reappear more rapidly after taking the XLCQ decoction than after conventional laxative treatment.Both the average aggregate constipation score and the time taken to achieve spontaneous bowel movements showed positive correlations with NIHSS scores before and1 month after treatment(P<0.01).CONCLUSION:Treatment with XLCQ decoction effectively alleviated the overall symptoms of constipation in acute ischemic stroke patients.The status of bowel movements in acute ischemic stroke can reflect the severity of neurological impairment and predict neurological outcomes at 1 month.展开更多
文摘目的探讨双水平气道正压通气(BiPAP)无创呼吸机通气联合肺康复治疗在老年护理机构慢性阻塞性肺疾病(COPD)稳定期合并高碳酸血症患者中的应用效果。方法选取2018年2月—2019年2月收治的47例老年COPD稳定期合并高碳酸血症接受肺康复的患者,采用随机数字表法随机分成研究组(n=23)和对照组(n=24)。对照组予低流量鼻导管吸氧、化痰、扩张支气管、布地奈德福莫特罗吸入剂、营养治疗、有氧训练、阻抗训练以及心理支持等治疗措施;研究组在对照组的治疗基础上联合给予无创BiPAP治疗。比较2组患者的临床疗效、血气指标、慢性阻塞性肺疾病评估测试(CAT)、6min步行试验(6MWT)、肺功能及并发症发生情况。结果治疗4周,研究组二氧化碳分压和6MWT的改善程度优于对照组,差异有统计学意义(P<0.05);研究组FEV1及FEV1占预计值百分比有所提升,且研究组改善情况优于对照组(P<0.05)。研究组临床疗效总有效率高于对照组(91.3% vs 62.5%,P=0.049),继发肺部感染的发生率低于对照组(26.1% vs 62.5%,P=0.037)。结论BiPAP无创呼吸机通气联合肺康复治疗在合并高碳酸血症的老年COPD稳定期患者中疗效显著,能有效改善患者的临床症状、血气指标及肺功能,降低二氧化碳潴留及呼吸性酸中毒,减少肺部感染的发生率。
基金Intervention Study on Traditional Chinese Medicine Granules and Jiangzhuo Formula,Combined with Life Style Guidance on Phlegm Constitution of Simple ObesityBeijing TCM Science and Technology Development Fund Project
文摘OBJECTIVE: To observe the clinical effect of oral traditional Chinese medicine granules combined with health education to regulate phlegm constitution and treat simple obesity. METHODS: According to the method of constitution evaluation in TCM Constitution Classification and Evaluation(Chinese Association of Chinese Medicine), the TCM classification of Chinese medicine was performed on patients who came to the outpatient department of the Traditional Chinese Medicine Hospital of Pinggu District of Beijing and met the diagnostic criteria of simple obesity. One hundred patients with phlegm constitution were selected and those in accordance with the standards, were randomly divided into group with oral TCM granules combined with health education(refer to as treatment group) and health education group(refer to as control group) according to 1:1 ratio. The control group was given health education including diet and exercise instruction. Treatment group:(1) Health education includes diet and exercise instruction.(2) Oral Chinese medicine granules: ingredients: atractylodes rhizome 15g, raw barley 30g, Folium Nelumbinis 10g, Chinese hawthorn fruit 10g, Chinese waxgourd peel 15g, milk-vetch root;15g, kudzuvine root 15g, danshen root10g, 2 times/d. The two groups were intervened for 12 weeks each time, and obesity evaluation indicators such as body weight, body fat, waist circumference, hip circumference, weight index, and score table of TCM constitutional were observed before and after the intervention. Statistical software was used for statistical analysis. RESULTS: The total curative effect of the treatment group was better than that of the control group(P<0.001). The weight index, body weight, waist and hip circumference decreased significantly after treatment(P <0.01). Compared with the two groups, the treatment group is better than the control group in terms of dampness constitution improvement, weight and fat losing and waist and hip circumference reducing.(P<0.01). CONCLUSION: Oral Chinese medicine granules Jiangzhuo Fang(combined with health education) and simple health education can improve phlegm constitution, and improve the body weight, body fat percentage and other indicators of the patients, but oral granules combined with health education to improve the physical fitness of phlegm is better than simple health education. The thoughts and methods of Chinese medicine granules combined with health education to regulate phlegm constitution is effective for weight losing and is worthy of further research and promotion.
基金Supported by the National Science and Technology Pillar Program during the 12th Five-year Plan Period of the People’s Republic of China(No.2013BAI13B02).
文摘OBJECTIVE:To evaluate the effectiveness of traditional Chinese herbal Xinglouchengqi(XLCQ)decoction for the treatment of constipation in acute ischemic stroke patients,and figure out the role that bowel movements play in the treatment of acute ischemic stroke.METHODS:A total of 317 eligible patients were recruited and randomized to the XLCQ group(211 patients)or the control group(106 patients).In addition to conventional standard medical care and rehabilitation,participants in the XLCQ group received XLCQ decoction,while the control group received clysis therapy using glycerin enemas or lactulose oral solution.Both groups were given treatment for 3 to 6 d,during which they received daily visits to record defecation features and accompanying symptoms.Neurological assessments using the National Institutes of Health Stroke Scale(NIHSS)were conducted before and 1 month after treatment.RESULTS:Patients in the XLCQ group had lower aggregate constipation scores compared with the control group on days 3 and 5(P<0.05).Spontaneous bowel movements tended to reappear more rapidly after taking the XLCQ decoction than after conventional laxative treatment.Both the average aggregate constipation score and the time taken to achieve spontaneous bowel movements showed positive correlations with NIHSS scores before and1 month after treatment(P<0.01).CONCLUSION:Treatment with XLCQ decoction effectively alleviated the overall symptoms of constipation in acute ischemic stroke patients.The status of bowel movements in acute ischemic stroke can reflect the severity of neurological impairment and predict neurological outcomes at 1 month.
