Discovering Cathodic Biocompatibility for Aqueous Zn–MnO_(2) Battery:An Integrating Biomass Carbon Strategy

Developing high-performance aqueous Zn-ion batteries from sustainable biomass becomes increasingly vital for large-scale energy storage in the foreseeable future.Therefore,γ-MnO_(2) uniformly loaded on N-doped carbon derived from grapefruit peel is successfully fabricated in this work,and particularly the composite cathode with carbon carrier quality percentage of 20 wt%delivers the specific capacity of 391.2 mAh g^(−1)at 0.1 A g^(−1),outstanding cyclic stability of 92.17%after 3000 cycles at 5 A g^(−1),and remarkable energy density of 553.12 Wh kg^(−1) together with superior coulombic efficiency of~100%.Additionally,the cathodic biosafety is further explored specifically through in vitro cell toxicity experiments,which verifies its tremendous potential in the application of clinical medicine.Besides,Zinc ion energy storage mechanism of the cathode is mainly discussed from the aspects of Jahn–Teller effect and Mn domains distribution combined with theoretical analysis and experimental data.Thus,a novel perspective of the conversion from biomass waste to biocompatible Mn-based cathode is successfully developed.

Research on Deformation Mode of the Longmenshan-Longriba Region Using GPS and Leveling Data

The Longmenshan-Longriba region is located on the eastern edge of the Tibetan Plateau, and is an ideal place to study the eastward extrusion and uplift mechanism of the plateau. Previous studies on this area mainly focused on tectonic activity and seismic hazard, with few studies giving its overall deformation characteristics and dynamic mechanism. This paper uses the latest dense GPS data, combined with precise Leveling data to analyze the kinematic characteristics and deformation mode of the Longmenshan fault zone (LMSF) and the Longriba fault zone (LRBF). The results show that both the Longmenshan fault zone and the Longriba fault zone have certain right-lateral strike-slip and thrusting, indicating that they play an important role in adjusting strain distribution and absorbing tectonic deformation;The strain-rate field on the Longriba fault zone is broadly distributed, suggesting that the deformation field is at least partially coupled;while the strain-rate field on the Longmenshan fault zone presents a non-uniform distribution, indicating different dynamic sources acting on segments. The high strain rate areas revealed in this study points us to the high-risk area for future earthquakes. The present-day vertical motion velocity field in the region obtained from Leveling and GPS data shows a mismatch between the regional deformation field and active tectonics, which can be explained by the incomplete coupling of deformation between the lower and upper crust.

Enhanced Redox Electrocatalysis in High‑Entropy Perovskite Fluorides by Tailoring d–p Hybridization

High-entropy catalysts featuring exceptional properties are,in no doubt,playing an increasingly significant role in aprotic lithium-oxygen batteries.Despite extensive effort devoted to tracing the origin of their unparalleled performance,the relationships between multiple active sites and reaction intermediates are still obscure.Here,enlightened by theoretical screening,we tailor a high-entropy perovskite fluoride(KCoMnNiMgZnF_(3)-HEC)with various active sites to overcome the limitations of conventional catalysts in redox process.The entropy effect modulates the d-band center and d orbital occupancy of active centers,which optimizes the d–p hybridization between catalytic sites and key intermediates,enabling a moderate adsorption of LiO_(2)and thus reinforcing the reaction kinetics.As a result,the Li–O2 battery with KCoMnNiMgZnF_(3)-HEC catalyst delivers a minimal discharge/charge polarization and long-term cycle stability,preceding majority of traditional catalysts reported.These encouraging results provide inspiring insights into the electron manipulation and d orbital structure optimization for advanced electrocatalyst.

Numerical methods for the magneto-mechanical coupling analysis of invessel components in Tokamak devices

Magneto-mechanical coupling vibration arises in the in-vessel components of Tokamak devices especially during the plasma disruption. Strong electromagnetic forces cause the structures to vibrate while the motion in turn changes the distribution of the electromagnetic field. To ensure the Tokamak devices operating in a designed state, numerical analysis on the coupling vibration is of great importance. This paper introduces two numerical methods for the magneto-mechanical coupling problems. The coupling term of velocity and magnetic flux density is manipulated in both Eulerian and Lagrangian description, which brings much simplification in numerical implementation. Corresponding numerical codes have been developed and applied to the dynamic simulation of a test module in J-TEXT and the vacuum vessel of HL-2M during plasma disruptions. The results reveal the evident influence of the magnetic stiffness and magnetic damping effects on the vibration behavior of the in-vessel structures. Finally, to deal with the halo current injection problem, a numerical scheme is described and validated which can simulate the distribution of the halo current without complicated manipulations.

ESRC guide vanes of hydraulic turbine for Three Gorges project

The mechanical properties and internal quality of low carbon martensite Electroslag Remelting Casting (ESRC)stainless steel castings are superior to that of sand casting ones. The key technologies for the equipments and ESRCprocesses have been resolved during the experimental research period of guide vanes of hydraulic turbines for ThreeGorges project. And ESRC guide vanes of hydraulic turbines for Three Gorges project have been produced successfully.

Chimeric antigen receptor-immune cells against solid tumors:Structures,mechanisms,recent advances,and future developments

The advent of chimeric antigen receptor(CAR)-T cell immunotherapies has led to breakthroughs in the treatment of hematological malignancies.However,their success in treating solid tumors has been limited.CAR-natural killer(NK)cells have several advantages over CAR-T cells because NK cells can be made from pre-existing cell lines or allogeneic NK cells with a mismatched major histocompatibility complex(MHC),which means they are more likely to become an"off-the-shelf"product.Moreover,they can kill cancer cells via CAR-dependent/independent pathways and have limited toxicity.Macrophages are the most malleable immune cells in the body.These cells can efficiently infiltrate into tumors and are present in large numbers in tumor microenvironments(TMEs).Importantly,CAR-macrophages(CAR-Ms)have recently yielded exciting preclinical results in several solid tumors.Nevertheless,CAR-T,CAR-NK,and CAR-M all have their own advantages and limitations.In this review,we systematically discuss the current status,progress,and the major hurdles of CAR-T cells,CAR-NK cells,and CAR-M as they relate to five aspects:CAR structure,therapeutic mechanisms,the latest research progress,current challenges and solutions,and comparison according to the existing research in order to provide a reasonable option for treating solid tumors in the future.

Adaptive Threshold Estimation of Open Set Voiceprint Recognition Based on OTSU and Deep Learning

Aiming at the problem of open set voiceprint recognition, this paper proposes an adaptive threshold algorithm based on OTSU and deep learning. The bottleneck technology of open set voiceprint recognition lies in the calculation of similarity values and thresholds of speakers inside and outside the set. This paper combines deep learning and machine learning methods, and uses a Deep Belief Network stacked with three layers of Restricted Boltzmann Machines to extract deep voice features from basic acoustic features. And by training the Gaussian Mixture Model, this paper calculates the similarity value of the feature, and further determines the threshold of the similarity value of the feature through OTSU. After experimental testing, the algorithm in this paper has a false rejection rate of 3.00% for specific speakers, a false acceptance rate of 0.35% for internal speakers, and a false acceptance rate of 0 for external speakers. This improves the accuracy of traditional methods in open set voiceprint recognition. This proves that the method is feasible and good recognition effect.

A Block Compressed Sensing for Images Selective Encryption in Cloud

The theory of compressed sensing(CS)has been proposed to reduce the processing time and accelerate the scanning process.In this paper,the image recovery task is considered to outsource to the cloud server for its abundant computing and storage resources.However,the cloud server is untrusted then may pose a considerable amount of concern for potential privacy leakage.How to protect data privacy and simultaneously maintain management of the image remains challenging.Motivated by the above challenge,we propose an image encryption algorithm based on chaotic system,CS and image saliency.In our scheme,we outsource the image CS samples to cloud for reduced storage and portable computing.Consider privacy,the scheme ensures the cloud to securely reconstruct image.Theoretical analysis and experiment show the scheme achieves effectiveness,efficiency and high security simultaneously.

Plasma levels of luteinizing hormone and prolactin in relation to double brooding in Great Tit(Parus major)

The reproductive behaviors of birds are mainly controlled by the hypothalamus-pituitary-gonad axis.Many studies have shown that reproductive hormones are tightly linked to the breeding sub-stages.However,only a few studies have examined the temporal trend of hormone levels among different reproductive stages in multiple brooded species.We investigated the changes in plasma luteinizing hormone(LH)and prolactin(PRL)concentrations during different reproductive stages of the facultative double-brooded Great Tit(Parus major).We found that the concentrations of LH and PRL in females were significantly higher than those in males.Females had significantly higher LH and lower PRL concentrations in the pre-breeding period than in the first/second brooding periods,and there were no significant changes between the first and second brooding periods.The concentrations of LH and PRL in males had no significant difference between the pre-breeding period and the first brooding periods,while LH and PRL concentrations in the second brooding period were significantly higher than those in the first brooding period.We conclude that there are sex-based differences between LH and PRL at different stages of reproduction.The changes in LH and PRL in both males and females should be related to their physiological functions.Especially for males,individuals with higher levels of LH and PRL are more likely to maintain second clutches.

Chip-based quantum communications

Quantum communications aim to share encryption keys between the transmitters and receivers governed by the laws of quantum mechanics.Integrated quantum photonics offers significant advantages of dense integration,high stability and scalability,which enables a vital platform for the implementation of quantum information processing and quantum communications.This article reviews recent experimental progress and advances in the development of integrated quantum photonic devices and systems for quantum communications and quantum networks.

Risks,challenges and strategies of power systems against the background of carbon neutrality

Building a new power system with new energy as the main body is an important means of achieving the goal of carbon neutrality.Compared with the traditional power system,the new power system has great changes and challenges in its safety mechanism and balance mechanism.Based on this,this paper focuses on the changes in the characteristics,functions and technologies of the new power system from the three sides of the source network and load.On this basis,the challenges faced by the high proportion of new-energy power systems are summarized from six aspects:reliability,stability,economy,data intelligence,flexibility and synergy.Finally,corresponding countermeasures,solutions and suggestions are put forward for the challenges of reliability,stability,economy,data intellectualization,flexibility and synergy,which provide ideas for the power guarantee of the new power system.

Numerical study on the effect of in-situ stress on smoothwall blasting in deep tunnelling

In the present study,a numerical model is first calibrated against the crack networks and pressure attenuation data in laboratory blasting test.Then,based on the calibrated numerical model,two-hole plane models are developed and used to perform a series of sim-ulations of smoothwall blasting in deep tunnelling subjected to in-situ stress.The evolutions of rock fracture and excavation damage zone in the roof/floor and sidewalls under different far-field hydrostatic pressure and anisotropic in-situ stress conditions are numerically investigated.The findings in numerical modelling are also analytically interpreted with the stress distributions around the designed tunnel perimeter and perimeter borehole.The numerical and analytical results show that the variations of rock cracking and excavation dam-aged zone induced by smoothwall blasting with in-situ stress are mainly attributed to the high tangential compressive stress concentration around the remaining rock after inner primary blasts and the tensile stress acting on the wall of perimeter hole,which control the crack propagation and initiation respectively.At last,the implications of findings for practical smoothwall blasting in deep tunnelling are discussed.

Spatial Dynamics of Chickenpox Outbreaks in Rapidly Developing Regions:Implications for Global Public Health

Objective The occurrence of chickenpox in rapidly developing areas poses substantial seasonal risk to children.However,certain factors influencing local chickenpox outbreaks have not been studied.Here,we examined the relationship between spatial clustering,heterogeneity of chickenpox outbreaks,and socioeconomic factors in Southern China.Methods We assessed chickenpox outbreak data from Southern China between 2006 and 2021,comprising both relatively fast-growing parts and slower sub-regions,and provides a representative sample of many developing regions.We analyzed the spatial clustering attributes associated with chickenpox outbreaks using Moran’s I and local indicators of spatial association and quantified their socioeconomic determinants using Geodetector q statistics.Results There were significant spatial heterogeneity in the risk of chickenpox outbreaks,with strong correlations between chickenpox risk and various factors,particularly demographics and living environment.Furthermore,interactive effects among specific are factors,such as population density and per capita residential building area,percentage of households with toilets,percentage of rental housing,exhibited q statistics of 0.28,0.25,and 0.24,respectively.Conclusion This study provides valuable insights into the spatial dynamics of chickenpox outbreaks in rapidly developing regions,revealing the socioeconomic factors affecting disease transmission.These implications extend the formulation of effective public health strategies and interventions to prevent and control chickenpox outbreaks in similar global contexts.

Pore Formation Mechanism in W-C Hard Coatings Using Directed Energy Deposition on Tungsten Alloy

Porosity is a common phenomenon and can significantly hinder the quality of the coating.Here,the pore formation mechanism and the characteristics of the single tracks of the W-C coating using directed energy deposition(DED)are systematically investigated.The forming quality of the tracks,the distribution of the pores,and the elemental distribution near the pores are analyzed by the observations of the cross-sections of the tracks.The temperature field of the melt pool is discussed comprehensively to reveal the pore formation mechanism.The results confirm that Ni and Co evaporated during the DED process due to the high temperature of the melt pool.Pores were continuously produced adjacent to the fusion line when the melt pool was about to solidify since the temperature at the solidification front was higher than the boiling point of Ni.The vaporization area at the fusion line was proposed,where Ni could also evaporate at the time the melt pool started to solidify.The relationship between the solidification rate,the size of the vaporization area and the DED parameters(laser power and scanning speed)was established to discuss the causes of severe pores above the fusion line.This work contains a practical guide to reduce or eliminate the porosity in the coating preparation process on the surface of the tungsten alloy.

Human gut microbiota： the links with dementia development

Dementia is a comprehensive category of brain diseases that is great enough to affect a person＇s daily functioning. The most common type of dementia is Alzheimer＇s disease, which makes most of cases. New researches indicate that gastrointestinal tract microbiota are directly linked to dementia pathogenesis through triggering metabolic diseases and low-grade inflammation progress. A novel strategy is proposed for the management of these disorders and as an adjuvant for psychiatric treatment of dementia and other related diseases through modulation of the microbiota （e.g. with the use of probiotics）.

Comparison of the osteogenic capability of rat bone mesenchymal stem cells on collagen,collagen/hydroxyapatite,hydroxyapatite and biphasic calcium phosphate

Collagen(COL),collagen/hydroxyapatite(COL/HA),HA and biphasic calcium phosphate were prepared as representative bone grafting materials with composition analogous to bone,and their structural characteristics were analyzed.The rat bone mesenchymal stem cells(BMSCs)were further seeded onto four groups of materials,and BMSCs grown in basic medium and standard osteogenic medium were set as controls of a reference model to show the basic and osteogenic behavior of cells without the intervention of materials.Cellular behaviors were characterized,including proliferation,spreading morphology and expression of osteogenesis factors.The rat BMSCs proliferated properly with time on four groups of materials as well on two groups of controls,and typical cuboidal,polygonal and extremely-elongated morphologies of cells were observed.According to the real-time polymerase chain reaction data,a higher osteogenic gene expression level was dependent upon the growing morphology but not the proliferation rate of cells,and the osteogenic differentiation capacity of cells onto four groups of materials varied in specific genes.In general,BMSCs exhibited the highest osteogenic capacity onto COL/HA,but the poorest onto HA.The growing behaviors of cells on materials were further discussed in comparison with the cases of OC and BC of the reference model.The present attempt to comparatively analyze cell experimental data with a reference model is expected to be useful for revealing the difference in the osteogenic capability of MSCs onto materials or even the bioactivity of materials.

Trends in Mortality of Low Birth Weight Infants-China,2004-2019

Summary What is already known about this topic?Low birth weight(LBW)significantly affects the health of children during the perinatal period,neonatal period,and infancy,and is an important risk factor for neonatal death.What is added by this report?The mortality rate of low birth weight infants(LBWI)decreased from 2004 to 2019 in China,while the proportion of overall infant deaths due to LBW increased.What are the implications for public health practices?A key way to reduce child mortality and improve children’s health is to reduce the occurrence of LBW and associated mortality.

The Incidence,Mortality,and DALYs Trends Associated with Esophageal Cancer-China,1990-2019

What is already known about this topic?Esophageal cancer(EC)is one of the most common malignant tumors in China.The new cases and deaths in China account for more than half of the world,and the disease burden of esophageal cancer is serious.What is added by this report?From 1990 to 2019,the disease burden of EC in China showed a decrease overall;it first increased between 1990 and 2004,but then decreased between 2004 and 2019.The burden of EC in men was much higher than that in women.Age was an important factor affecting the burden of EC,with disease burden rising rapidly after 40 years old.What are the implications for public health practices?The screening,early diagnosis,and treatment for EC should continue to be strengthened in China.Middleaged and elderly men are high-risk groups of EC and should be a key population for EC prevention and control.

Topological Similarity-Based Multi-Target Correlation Localization for Aerial-Ground Systems

In this paper,an algorithm for solving the multi-target correlation and co-location problem of aerial-ground heterogeneous system is investigated.Aiming at the multi-target correlation problem,the fusion algorithm of visual axis correlation method and improved topological similarity correlation method are adopted in view of large parallax and inconsistent scale between the aerial and ground perspectives.First,the visual axis was preprocessed by the threshold method,so that the sparse targets were initially associated.Then,the improved topological similarity method was used to further associate dense targets with the relative position characteristics between targets.The shortcoming of dense target similarity with small di®erence was optimized by the improved topological similarity method.For the problem of colocation,combined with the multi-target correlation algorithm in this paper,the triangulation positioning model was used to complete the co-location of multiple targets.In the experimental part,simulation experiments and°ight experiments were designed to verify the e®ectiveness of the algorithm.Experimental results show that the proposed algorithm can e®ectively achieve multi-target correlation positioning,and that the positioning accuracy is obviously better than other positioning methods.

A bioinspired bubble removal method in microchannels based on angiosperm xylem embolism repair

It is difficult to remove and eliminate bubbles in microchannels in many devices used in various biomedical fields,such as those needed for microfluidic immunoassays,point-of-care testing,and cell biology evaluations.Accumulated bubbles are associated with a number of negative outcomes,including a decrease in device sensitivity,inaccuracy of analysis results,and even functional failure.Xylem conduits of angiosperm have the ability to remove bubbles in obstructed conduits.Inspired by such an embolism repair mechanism,this paper proposes a bioinspired bubble removal method,which exhibits a prominent ability to dissolve bubbles continuously within a large range of flow rates(2μL/min-850 plVmin)while retaining the stability and continuity of the flow without auxiliary equipment.Such a method also shows significant bubble removal stability in dealing with Newtonian liquids and non-Newtonian fluids,especially with high viscosity(6.76 Pa s)and low velocity(152 nL/min).Such advantages associated with the proposed bioinspired method reveal promising application prospects in macro/microfluidic fields ranging from 3D printing,implantable devices,virus detection,and biomedical fluid processing to microscale reactor operation and beyond.