BACKGROUND Some patients present to the intensive care unit due to noninfectious pathologies resulting in fever,especially acute neurological injuries,including brain trauma and intracranial haemorrhage.The cause has ...BACKGROUND Some patients present to the intensive care unit due to noninfectious pathologies resulting in fever,especially acute neurological injuries,including brain trauma and intracranial haemorrhage.The cause has been identified to be central hyperthermia characterized by a high core temperature and a poor response to antipyretics and antibiotics.However,no proper guidelines on how to treat central hyperthermia have been developed for clinical practice.CASE SUMMARY A 63-year-old woman was transferred to our hospital due to injury after a traffic accident.Eight hours after admission,her pupils enlarged bilaterally from 2.5 mm to 4.0 mm.She developed severe coma and underwent decompressive craniectomy.She was diagnosed with central hyperthermia after surgery and was prescribed bromocriptine.The standard dose of bromocriptine could not control her hyperpyrexia,and we prescribed 30 mg a day to control her temperature.CONCLUSION Bromocriptine may be effective in controlling central hyperthermia and have a dosage effect.展开更多
Primary Sjogren’s syndrome is a chronic autoimmune disease that can lead to systemic manifestations.At present,immunomodulatory agents have not shown good efocacy,many patients in China seek Chinese medicine treatmen...Primary Sjogren’s syndrome is a chronic autoimmune disease that can lead to systemic manifestations.At present,immunomodulatory agents have not shown good efocacy,many patients in China seek Chinese medicine treatment.Chinese medicine can comprehensively improve the symptoms of patients through Chinese pattern diagnosis and individualized treatment.Fundamental researches are providing scientioc bases for the therapeutic effect of Chinese medicine.Professional Chinese medicine treatment can be integrated into the conventional management of primary Sjogren’s syndrome.展开更多
文摘BACKGROUND Some patients present to the intensive care unit due to noninfectious pathologies resulting in fever,especially acute neurological injuries,including brain trauma and intracranial haemorrhage.The cause has been identified to be central hyperthermia characterized by a high core temperature and a poor response to antipyretics and antibiotics.However,no proper guidelines on how to treat central hyperthermia have been developed for clinical practice.CASE SUMMARY A 63-year-old woman was transferred to our hospital due to injury after a traffic accident.Eight hours after admission,her pupils enlarged bilaterally from 2.5 mm to 4.0 mm.She developed severe coma and underwent decompressive craniectomy.She was diagnosed with central hyperthermia after surgery and was prescribed bromocriptine.The standard dose of bromocriptine could not control her hyperpyrexia,and we prescribed 30 mg a day to control her temperature.CONCLUSION Bromocriptine may be effective in controlling central hyperthermia and have a dosage effect.
基金Supported by National Natural Science Foundation of China(No.81573925)Scientific Research Program of Shanghai Science and Technology Commission(No.17401935500)Accurate Diagnosis and Treatment of Difficult Diseases from Shanghai Hospital Development Center(No.16CR2047B)。
文摘Primary Sjogren’s syndrome is a chronic autoimmune disease that can lead to systemic manifestations.At present,immunomodulatory agents have not shown good efocacy,many patients in China seek Chinese medicine treatment.Chinese medicine can comprehensively improve the symptoms of patients through Chinese pattern diagnosis and individualized treatment.Fundamental researches are providing scientioc bases for the therapeutic effect of Chinese medicine.Professional Chinese medicine treatment can be integrated into the conventional management of primary Sjogren’s syndrome.
