Design and development of new tactics and strategies to improve synthetic efficiency is a hot topic and main concern in nowadays’chemical synthesis of bioactive natural products.Cascade reactions,which construct seve...Design and development of new tactics and strategies to improve synthetic efficiency is a hot topic and main concern in nowadays’chemical synthesis of bioactive natural products.Cascade reactions,which construct several bonds in one step via an orchestrated sequence,have been regarded as an important tactic to rapidly increase the molecular complexity,therefor to improve the synthetic efficiency.In this perspective account,we demonstrated and highlighted the significance of cascade reaction developments and applications in concise syntheses of bioactive alkaloids based on our own recent adventure in this research field.展开更多
基金National Natural Science Foundation of China(Nos.21125207,21572088 and 21871118).
文摘Design and development of new tactics and strategies to improve synthetic efficiency is a hot topic and main concern in nowadays’chemical synthesis of bioactive natural products.Cascade reactions,which construct several bonds in one step via an orchestrated sequence,have been regarded as an important tactic to rapidly increase the molecular complexity,therefor to improve the synthetic efficiency.In this perspective account,we demonstrated and highlighted the significance of cascade reaction developments and applications in concise syntheses of bioactive alkaloids based on our own recent adventure in this research field.
