Synthesis of Heterometallic Rare Earth(Ⅲ)-Cobalt(Ⅱ)Complexes and Their Application in Alternating Copolymerization of Cyclohexene Oxide and Carbon Dioxide

Comprehensive Summary Four heterometallic rare earth(Ⅲ)-cobalt(Ⅱ)complexes(rare earth=Y(1),Sm(2),Nd(3),La(4))stabilized by an o-phenylenediamine-bridged tris(phenolato)ligand(L)have been synthesized and characterized.In these tetranuclear complexes,one polydentate L coordinates to one rare earth(Ⅲ)ion,and one cobalt(Ⅱ)ion,respectively,while two rare earth ions are bridged by four acetate groups.These complexes were applied in the copolymerization of cyclohexene oxide and CO_(2),which showed good activity(TON up to 440)and high poly(cyclohexene carbonate)selectivity(>99%).Kinetic studies determined the equation as rate=k[CHO]1[CO_(2)]0[initiator]1,which proves a first-order dependence on initiator concentrations and implies a synergistic mechanism with rare earth and cobalt ions cooperating in epoxide ring-opening and chain propagation.

MRI-derived radiomics models for diagnosis,aggressiveness,and prognosis evaluation in prostate cancer

Prostate cancer(PCa)is a pernicious tumor with high heterogeneity,which creates a conundrum for making a precise diagnosis and choosing an optimal treatment approach.Multiparametric magnetic resonance imaging(mp-MRI)with anatomical and functional sequences has evolved as a routine and significant paradigm for the detection and characterization of PCa.Moreover,using radiomics to extract quantitative data has emerged as a promising field due to the rapid growth of artificial intelligence(AI)and image data processing.Radiomics acquires novel imaging biomarkers by extracting imaging signatures and establishes models for precise evaluation.Radiomics models provide a reliable and noninvasive alternative to aid in precision medicine,demonstrating advantages over traditional models based on clinicopathological parameters.The purpose of this review is to provide an overview of related studies of radiomics in PCa,specifically around the development and validation of radiomics models using MRI-derived image features.The current landscape of the literature,focusing mainly on PCa detection,aggressiveness,and prognosis evaluation,is reviewed and summarized.Rather than studies that exclusively focus on image biomarker identification and method optimization,models with high potential for universal clinical implementation are identified.Furthermore,we delve deeper into the critical concerns that can be addressed by different models and the obstacles that may arise in a clinical scenario.This review will encourage researchers to design models based on actual clinical needs,as well as assist urologists in gaining a better understanding of the promising results yielded by radiomics.

Synthesis of Benzoxazine Functionalized Amine-Bridged Bis(phenolato) Rare Earth Complexes and Their Application in Ring-Opening Polymerization of rac-Lactide

The reactivities of benzoxazine functionalized amine bridged bis(phenol)s LnH_(2)(n=1—3)with rare earth metal complexes were explored,founding that both the aryl substituents of the ligand and the rare earth metals have profound influences on reaction outcomes.