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Augmentation of antitumor effects by fibroblast-mediated IL-2 and IL-3 gene therapy in mice treated with chemotherapy and BMT
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作者 xuetao cao, qing li, dianwen ju, quanxing wang, weiping zhang, qun taodepartment of immunology, the second military medical university, shanghai 200433 《中国实验血液学杂志》 CAS CSCD 1997年第3期322-323,共2页
Effects of fibroblast-mediated IL-2 and IL-3 genetherapy on recovery of bone marrow depression in tumor-bearing mice treated with cyclophosphamide (300 mg/kg) and syngeneic BMT were investigated in the presentreport. ... Effects of fibroblast-mediated IL-2 and IL-3 genetherapy on recovery of bone marrow depression in tumor-bearing mice treated with cyclophosphamide (300 mg/kg) and syngeneic BMT were investigated in the presentreport. BALB/c mice were inoculated with J558Lplasmacytoma cells s. c. and 3 days later IL-2 secretingNIH3T3-IL-2, IL-3 secreting NIH3T3-IL-3 fibroblastcells were implanted into the tumor-bearing mice 展开更多
关键词 ANTITUMOR CHEMOTHERAPY implanted alone inoculated PROLONGED inhibited markedly cytotoxicity implantation
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