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Synthesis of a Photolabeling Probe for the Study of Antiviral Mechanism of Ribavirin 被引量:1
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作者 QiongYouwu xunzhu +2 位作者 JinQiaoWAN FanQiQU LingPENG 《Chinese Chemical Letters》 SCIE CAS CSCD 2004年第8期907-910,共4页
Ribavirin has been used in urgency to treat SARS patients recently. In order to study its antiviral mechanism by photolabeling approach, we have synthesized and characterized 5-azido-1-β-D-ribofuranosyl-1,2,4-triazol... Ribavirin has been used in urgency to treat SARS patients recently. In order to study its antiviral mechanism by photolabeling approach, we have synthesized and characterized 5-azido-1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxiamide 1 as a photolabeling probe of ribavirin. The azidotriazole nucleoside showed rapid and clean photochemical reaction, suggesting that l is a promising probe to study the antiviral mechanism of ribarivin by photolabeling. 展开更多
关键词 RIBAVIRIN photolabeling probe of ribavirin azidotriazole nucleoside azole nucleosides photolabeling.
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