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激光诱导击穿光谱(LIBS)分析虚拟仿真实验
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作者 张天龙 周嘉俊 +3 位作者 汤宏胜 宁晓辉 李延 李华 《大学化学》 CAS 2024年第6期295-302,共8页
虚拟仿真实验作为大型仪器分析实验教学模式的新兴趋势,有效地将虚拟仿真技术与实物仪器教学相结合,最大限度地提升了学生对于大型仪器分析的综合应用能力。本文以激光诱导击穿光谱(LIBS)虚拟仿真实验系统为例,完整地模拟了LIBS系统的... 虚拟仿真实验作为大型仪器分析实验教学模式的新兴趋势,有效地将虚拟仿真技术与实物仪器教学相结合,最大限度地提升了学生对于大型仪器分析的综合应用能力。本文以激光诱导击穿光谱(LIBS)虚拟仿真实验系统为例,完整地模拟了LIBS系统的样品处理、光谱采集、定性分析和定量分析等实际实验场景,通过虚实结合实验教学模式对实验过程进行实时跟踪与综合考评。该实验有助于提高学生自主探究能力和创新意识,培养具有独立思考与实践能力的拔尖人才。 展开更多
关键词 虚拟仿真实验 激光诱导击穿光谱 仪器分析实验 自主性 创造性
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Laparoscopic left hemihepatectomy guided by indocyanine green fluorescence: A cranial-dorsal approach 被引量:1
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作者 Xing-Ru Wang Xiao-Ju li +6 位作者 Dan-Dan Wan Qian Zhang Tian-Xi liu Zong-Wen Shen Hong-Xing Tong yan li Jian-Wei li 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第2期409-418,共10页
BACKGROUND Advancements in laparoscopic technology and a deeper understanding of intra-hepatic anatomy have led to the establishment of more precise laparoscopic hepatectomy(LH)techniques.The indocyanine green(ICG)flu... BACKGROUND Advancements in laparoscopic technology and a deeper understanding of intra-hepatic anatomy have led to the establishment of more precise laparoscopic hepatectomy(LH)techniques.The indocyanine green(ICG)fluorescence navi-gation technique has emerged as the most effective method for identifying hepatic regions,potentially overcoming the limitations of LH.While laparoscopic left hemihepatectomy(LLH)is a standardized procedure,there is a need for innova-tive strategies to enhance its outcomes.important anatomical markers,surgical skills,and ICG staining methods.METHODS Thirty-seven patients who underwent ICG fluorescence-guided LLH at Qujing Second People's Hospital between January 2019 and February 2022 were retrospectively analyzed.The cranial-dorsal approach was performed which involves dissecting the left hepatic vein cephalad,isolating the Arantius ligament,exposing the middle hepatic vein,and dissecting the parenchyma from the dorsal to the foot in order to complete the anatomical LLH.The surgical methods,as well as intra-and post-surgical data,were recorded and analyzed.Our hospital’s Medical Ethics Committee approved this study(Ethical review:2022-019-01).RESULTS Intraoperative blood loss during LLH was 335.68±99.869 mL and the rates of transfusion and conversion to laparotomy were 13.5%and 0%,respectively.The overall incidence of complications throughout the follow-up(median of 18 months;range 1-36 months)was 21.6%.No mortality or severe complications(level IV)were reported.CONCLUSION LLH has the potential to become a novel,standardized approach that can effectively,safely,and simply expose the middle hepatic vein and meet the requirements of precision surgery. 展开更多
关键词 Laparoscopic left hemihepatectomy Indocyanine green Cranial-dorsal approach Laparoscopic hepatectomy Arantius ligament Glissonean pedicle
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Potential evaluation of saline aquifers for the geological storage of carbon dioxide: A case study of saline aquifers in the Qian-5 member in northeastern Ordos Basin
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作者 yan li Peng li +4 位作者 Hong-jun Qu Gui-wen Wang Xiao-han Sun Chang Ma Tian-xing Yao 《China Geology》 CAS CSCD 2024年第1期12-25,共14页
The well-developed coal electricity generation and coal chemical industries have led to huge carbon dioxide(CO_(2))emissions in the northeastern Ordos Basin.The geological storage of CO_(2) in saline aquifers is an ef... The well-developed coal electricity generation and coal chemical industries have led to huge carbon dioxide(CO_(2))emissions in the northeastern Ordos Basin.The geological storage of CO_(2) in saline aquifers is an effective backup way to achieve carbon neutrality.In this case,the potential of saline aquifers for CO_(2) storage serves as a critical basis for subsequent geological storage project.This study calculated the technical control capacities of CO_(2) of the saline aquifers in the fifth member of the Shiqianfeng Formation(the Qian-5 member)based on the statistical analysis of the logging and the drilling and core data from more than 200 wells in the northeastern Ordos Basin,as well as the sedimentary facies,formation lithology,and saline aquifer development patterns of the Qian-5 member.The results show that(1)the reservoirs of saline aquifers in the Qian-5 member,which comprise distributary channel sand bodies of deltaic plains,feature low porosities and permeabilities;(2)The study area hosts three NNE-directed saline aquifer zones,where saline aquifers generally have a single-layer thickness of 3‒8 m and a cumulative thickness of 8‒24 m;(3)The saline aquifers of the Qian-5 member have a total technical control capacity of CO_(2) of 119.25×10^(6) t.With the largest scale and the highest technical control capacity(accounting for 61%of the total technical control capacity),the Jinjie-Yulin saline aquifer zone is an important prospect area for the geological storage of CO_(2) in the saline aquifers of the Qian-5 member in the study area. 展开更多
关键词 Carbon burial Carbon neutral CO_(2) storage in saline aquifer Distributary channel sand body Potential evaluation Technical control capacity CO_(2)geological storage engineering Ordos Basin
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Membrane vesicles derived from Streptococcus suis serotype 2 induce cell pyroptosis in endothelial cells via the NLRP3/Caspase-1/GSDMD pathway
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作者 Keda Shi yan li +4 位作者 Minsheng Xu Kunli Zhang Hongchao Gou Chunling li Shaolun Zhai 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2024年第4期1338-1353,共16页
Streptococcus suis serotype 2(S.suis 2)is a zoonotic pathogen that clinically causes severe swine and human infections(such as meningitis,endocarditis,and septicemia).In order to cause widespread diseases in different... Streptococcus suis serotype 2(S.suis 2)is a zoonotic pathogen that clinically causes severe swine and human infections(such as meningitis,endocarditis,and septicemia).In order to cause widespread diseases in different organs,S.suis 2 must colonize the host,break the blood barrier,and cause exaggerated inflammation.In the last few years,most studies have focused on a single virulence factor and its influences on the host.Membrane vesicles(MVs)can be actively secreted into the extracellular environment contributing to bacteria-host interactions.Gram-negative bacteria-derived outer membrane vesicles(OMVs)were recently shown to activate host Caspase-11-mediated non-canonical inflammasome pathway via deliverance of OMV-bound lipopolysaccharide(LPS),causing host cell pyroptosis.However,little is known about the effect of the MVs from S.suis 2(Gram-positive bacteria without LPS)on cell pyroptosis.Thus,we investigated the molecular mechanism by which S.suis 2 MVs participate in endothelial cell pyroptosis.In this study,we used proteomics,electron scanning microscopy,fluorescence microscope,Western blotting,and bioassays,to investigate the MVs secreted by S.suis 2.First,we demonstrated that S.suis 2 secreted MVs with an average diameter of 72.04 nm,and 200 proteins in MVs were identified.Then,we showed that MVs were transported to cells via mainly dynamin-dependent endocytosis.The S.suis 2 MVs activated NLRP3/Caspase-1/GSDMD canonical inflammasome signaling pathway,resulting in cell pyroptosis,but it did not activate the Caspase-4/-5 pathway.More importantly,endothelial cells produce large amounts of reactive oxygen species(ROS)and lost their mitochondrial membrane potential under induction by S.suis 2 MVs.The results in this study suggest for the first time that MVs from S.suis 2 were internalized by endothelial cells via mainly dynamin-dependent endocytosis and might promote NLRP3/Caspase-1/GSDMD pathway by mitochondrial damage,which produced mtDNA and ROS under induction,leading to the pyroptosis of endothelial cells. 展开更多
关键词 Streptococcus suis serotype 2 membrane vesicles ENDOCYTOSIS PYROPTOSIS NLRP3 inflammasomes mitochondrial damage endothelial cell
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Xuebijing improves intestinal microcirculation dysfunction in septic rats by regulating the VEGF-A/PI3K/Akt signaling pathway
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作者 A-ling Tang yan li +4 位作者 li-chao Sun Xiao-yu liu Nan Gao Sheng-tao yan Guo-qiang Zhang 《World Journal of Emergency Medicine》 SCIE CAS CSCD 2024年第3期206-213,共8页
BACKGROUND:This study aims to explore whether Xuebijing(XBJ) can improve intestinal microcirculation dysfunction in sepsis and its mechanism.METHODS:A rat model of sepsis was established by cecal ligation and puncture... BACKGROUND:This study aims to explore whether Xuebijing(XBJ) can improve intestinal microcirculation dysfunction in sepsis and its mechanism.METHODS:A rat model of sepsis was established by cecal ligation and puncture(CLP).A total of 30 male SD rats were divided into four groups:sham group,CLP group,XBJ + axitinib group,and XBJ group.XBJ was intraperitoneally injected 2 h before CLP.Hemodynamic data(blood pressure and heart rate) were recorded.The intestinal microcirculation data of the rats were analyzed via microcirculation imaging.Enzyme-linked immunosorbent assay(ELISA) kits were used to detect the serum levels of interleukin-6(IL-6),C-reactive protein(CRP),and tumor necrosis factor-α(TNF-α) in the rats.Histological analysis and transmission electron microscopy were used to analyze the injury of small intestinal microvascular endothelial cells and small intestinal mucosa in rats.The expression of vascular endothelial growth factor A(VEGF-A),phosphoinositide 3-kinase(PI3K),phosphorylated PI3K(p-PI3K),protein kinase B(Akt),and phosphorylated Akt(p-Akt) in the small intestine was analyzed via Western blotting.RESULTS:XBJ improved intestinal microcirculation dysfunction in septic rats,alleviated the injury of small intestinal microvascular endothelial cells and small intestinal mucosa,and reduced the systemic inflammatory response.Moreover,XBJ upregulated the expression of VEGF-A,p-PI3K/total PI3K,and p-Akt/total Akt in the rat small intestine.CONCLUSION:XBJ may improve intestinal microcirculation dysfunction in septic rats possibly through the VEGF-A/PI3K/Akt signaling pathway. 展开更多
关键词 SEPSIS XUEBIJING Vascular endothelial growth factor A MICROCIRCULATION Rat Phosphoinositide 3-kinase Protein kinase B
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Evaluating soil acidification risk and its effects on biodiversity–ecosystem multifunctionality relationships in the drylands of China
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作者 Lan Du Shengchuan Tian +5 位作者 Nan Zhao Bin Zhang Xiaohan Mu lisong Tang Xinjun Zheng yan li 《Forest Ecosystems》 SCIE CSCD 2024年第2期162-171,共10页
Background:Soil acidifcationn caused by anthropogenic activities may aft soil biochemical cydling,bidiversity,productivity,and multiple eosystem-related functions in drylands.However,to date,such information is lackin... Background:Soil acidifcationn caused by anthropogenic activities may aft soil biochemical cydling,bidiversity,productivity,and multiple eosystem-related functions in drylands.However,to date,such information is lacking to support this hypothesis.Methods Based on a transect survey of 78 naturally assembled shrub communities,we caloulated acid deposition flux in Northwest China and evaluated its likely ecological ffets by testing three altemnative hypotheses,namely:.nidche complementarity,mass ratio,and vegetation quantity hypotheses Rao's quadratic entopy and community-weighted mean traits were employed to represent the complementary aspect of niche complementarity and mass ratio effects,respectively.Resulbs:We observed that in the past four decades,the concentrations of exchangeable base cations in soil in Northwest China have decreased significantly to the extent of having faced the risk of depletion,whereas changes in the calium carbonate content and pH of soil were not significant.Adid deposition primani ly increased the aboweground biomass and shrub density in shrublands but had no sigmificant effect on shrub richness and ecasystem multifunctionality(EMF),indicating that acid deposition had positive but weak ecological effects on dryland ecosystems.Community wd ghted mean of functional traits(representing the mass ratio hypothesis)correlated negatively with EMF,whereas both Rao's quadratic entropy(representing the niche complementarity hypothesis)and aboveground biomass(representing the vegetation quantity hypothesis)correlated positively but insignifcantly with EMF.These biodiversity-EMF relationships highlight the fragility and instability of drylands relative to forest ecasystems.Concuions:The findings from this study serve as important reference points to understand the ris of soil acidification in arid regions and its impacts on biodiversity-EMF relationships. 展开更多
关键词 Soil acidification risk BIODIVERSITY Ecosystem multifunctionality Niche complementarity hypothesis Mass ratio hypothesis Vegetation quantity hypothesis
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A Modified Iterative Learning Control Approach for the Active Suppression of Rotor Vibration Induced by Coupled Unbalance and Misalignment
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作者 Yifan Bao Jianfei Yao +1 位作者 Fabrizio Scarpa yan li 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2024年第1期242-253,共12页
This paper proposes a modified iterative learning control(MILC)periodical feedback-feedforward algorithm to reduce the vibration of a rotor caused by coupled unbalance and parallel misalignment.The control of the vibr... This paper proposes a modified iterative learning control(MILC)periodical feedback-feedforward algorithm to reduce the vibration of a rotor caused by coupled unbalance and parallel misalignment.The control of the vibration of the rotor is provided by an active magnetic actuator(AMA).The iterative gain of the MILC algorithm here presented has a self-adjustment based on the magnitude of the vibration.Notch filters are adopted to extract the synchronous(1×Ω)and twice rotational frequency(2×Ω)components of the rotor vibration.Both the notch frequency of the filter and the size of feedforward storage used during the experiment have a real-time adaptation to the rotational speed.The method proposed in this work can provide effective suppression of the vibration of the rotor in case of sudden changes or fluctuations of the rotor speed.Simulations and experiments using the MILC algorithm proposed here are carried out and give evidence to the feasibility and robustness of the technique proposed. 展开更多
关键词 Rotor vibration suppression Modified iterative learning control UNBALANCE Parallel misalignment Active magnetic actuator
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Selective core-shell doping enabling high performance 4.6 V-LiCoO_(2)
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作者 Yueming Xia Jianrui Feng +6 位作者 Jinhui li yan li Zhengfeng Zhang Xiaoqi Wang Jianli Shao Manling Sui Pengfei yan 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第8期684-693,I0015,共11页
Constructing robust surface and bulk structure is the prerequisite for realizing high performance high voltage LiCoO_(2)(LCO).Herein,we manage to synthesize a surface Mg-doping and bulk Al-doping coreshell structured ... Constructing robust surface and bulk structure is the prerequisite for realizing high performance high voltage LiCoO_(2)(LCO).Herein,we manage to synthesize a surface Mg-doping and bulk Al-doping coreshell structured LCO,which demonstrates excellent cycling performance.Half-cell shows 94.2%capacity retention after 100 cycles at 3.0-4.6 V(vs.Li/Li^(+))cycling,and no capacity decay after 300 cycles for fullcell test(3.0-4.55 V).Based on comprehensive microanalysis and theoretical calculations,the degradation mechanisms and doping effects are systematically revealed.For the undoped LCO,high voltage cycling induces severe interfacial and bulk degradations,where cracks,stripe defects,fatigue H2 phase,and spinel phase are identified in grain bulk.For the doped LCO,Mg-doped surface shell can suppress the interfacial degradations,which not only stabilizes the surface structure by forming a thin rock-salt layer but also significantly improves the electronic conductivity,thus enabling superior rate performance.Bulk Al-doping can suppress the lattice"breathing"effect and the detrimental H3 to H1-3 phase transition,which minimizes the internal strain and defects growth,maintaining the layered structure after prolonged cycling.Combining theoretical calculations,this work deepens our understanding of the doping effects of Mg and Al,which is valuable in guiding the future material design of high voltage LCO. 展开更多
关键词 Lithium-ion battery Doping effect Failure mechanism High-voltage LiCoO_(2) Electron microscopy
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Self-derivation and reconstruction of silver nanoparticle reinforced cobalt-nickel bimetallic hydroxides through interface engineering for overall water splitting
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作者 yan li Jie Han +5 位作者 Weiwei Bao Junjun Zhang Taotao Ai Mameng yang Chunming yang Pengfei Zhang 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第3期590-599,I0013,共11页
Designing efficient and long-lasting non-metal electrocatalysts is an urgent task for addressing the issue of kinetic hysteresis in electrochemical oxidation reactions.The bimetallic hydroxides,catalyzing the oxygen e... Designing efficient and long-lasting non-metal electrocatalysts is an urgent task for addressing the issue of kinetic hysteresis in electrochemical oxidation reactions.The bimetallic hydroxides,catalyzing the oxygen evolution reaction(OER),have significant research potential because hydroxide reconstruction to generate an active phase is a remarkable advantage.Herein,the complete reconstruction of ultrathin CoNi(OH)_(2) nanosheets was achieved by embedding Ag nanoparticles into the hydroxide to induce a spontaneous redox reaction(SRR),forming heterojunction Ag@CoNi(OH)_(2) for bifunctional hydrolysis.Theoretical calculations and in situ Raman and ex situ characterizations revealed that the inductive effect of the Ag cation redistributed the charge to promote phase transformation to highly activate Ag-modified hydroxides.The Co-Ni dual sites in Co/NiOOH serve as novel active sites for optimizing the intermediates,thereby weakening the barrier formed by OOH^*.Ag@CoNi(OH)_(2) required a potential of 1.55 V to drive water splitting at a current density of 10 mA cm^(-2),with nearly 98.6% Faraday efficiency.Through ion induction and triggering of electron regulation in the OER via the synergistic action of the heterogeneous interface and surface reconstruction,this strategic design can overcome the limited capacity of bimetallic hydroxides and bridge the gap between the basic theory and industrialization of water decomposition. 展开更多
关键词 Surface reconstruction Bimetallic hydroxides Ag nanoparticle Operando Raman Overall water splitting
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Coated sodium butyrate ameliorates high‑energy and low‑protein diet induced hepatic dysfunction via modulating mitochondrial dynamics, autophagy and apoptosis in laying hens
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作者 Sasa Miao Tianming Mu +5 位作者 Ru li yan li Wenyan Zhao Jiankui li Xinyang Dong Xiaoting Zou 《Journal of Animal Science and Biotechnology》 SCIE CAS CSCD 2024年第3期1190-1206,共17页
Background Fatty liver hemorrhagic syndrome(FLHS),a fatty liver disease in laying hens,poses a grave threat to the layer industry,stemming from its ability to trigger an alarming plummet in egg production and usher in... Background Fatty liver hemorrhagic syndrome(FLHS),a fatty liver disease in laying hens,poses a grave threat to the layer industry,stemming from its ability to trigger an alarming plummet in egg production and usher in acute mortality among laying hens.Increasing evidence suggests that the onset and progression of fatty liver was closely related to mitochondria dysfunction.Sodium butyrate was demonstrated to modulate hepatic lipid metabolism,alle-viate oxidative stress and improve mitochondrial dysfunction in vitro and mice models.Nevertheless,there is limited existing research on coated sodium butyrate(CSB)to prevent FLHS in laying hens,and whether and how CSB exerts the anti-FLHS effect still needs to be explored.In this experiment,the FLHS model was induced by administering a high-energy low-protein(HELP)diet in laying hens.The objective was to investigate the effects of CSB on alleviating FLHS with a focus on the role of CSB in modulating mitochondrial function.Methods A total of 288 healthy 28-week-old Huafeng laying hens were arbitrarily allocated into 4 groups with 6 replicates each,namely,the CON group(normal diet),HELP group(HELP diet),CH500 group(500 mg/kg CSB added to HELP diet)and CH750 group(750 mg/kg CSB added to HELP diet).The duration of the trial encompassed a period of 10 weeks.Results The result revealed that CSB ameliorated the HELP-induced FLHS by improving hepatic steatosis and patho-logical damage,reducing the gene levels of fatty acid synthesis,and promoting the mRNA levels of key enzymes of fatty acid catabolism.CSB reduced oxidative stress induced by the HELP diet,upregulated the activity of GSH-Px and SOD,and decreased the content of MDA and ROS.CSB also mitigated the HELP diet-induced inflammatory response by blocking TNF-α,IL-1β,and F4/80.In addition,dietary CSB supplementation attenuated HELP-induced activation of the mitochondrial unfolded protein response(UPRmt),mitochondrial damage,and decline of ATPase activity.HELP diet decreased the autophagosome formation,and downregulated LC3B but upregulated p62 protein expression,which CSB administration reversed.CSB reduced HELP-induced apoptosis,as indicated by decreases in the Bax/Bcl-2,Caspase-9,Caspase-3,and Cyt C expression levels.Conclusions Dietary CSB could ameliorate HELP diet-induced hepatic dysfunction via modulating mitochondrial dynamics,autophagy,and apoptosis in laying hens.Consequently,CSB,as a feed additive,exhibited the capacity to prevent FLHS by modulating autophagy and lipid metabolism. 展开更多
关键词 AUTOPHAGY Coated sodium butyrate Laying hens Lipid metabolism MITOCHONDRIA
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VPD modifies CO_(2) fertilization effect on tomato plants via abscisic acid and jasmonic acid signaling pathways
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作者 Dalong Zhang Huihua yang +5 位作者 Xiaolu Chen yan li Yunzhou li Hongye liu Xulin Wu Min Wei 《Horticultural Plant Journal》 SCIE CAS CSCD 2024年第5期1165-1176,共12页
Atmospheric CO_(2)concentration is elevated globally,which has“CO_(2)fertilization effects”and potentially improves plant photosynthesis,yield,and productivity.Despite the beneficial effect of CO_(2)fertilization be... Atmospheric CO_(2)concentration is elevated globally,which has“CO_(2)fertilization effects”and potentially improves plant photosynthesis,yield,and productivity.Despite the beneficial effect of CO_(2)fertilization being modulated by vapor pressure deficit(VPD),the underlying mechanism is highly uncertain.In the present study,the potential roles of hormones in determining CO_(2)fertilization effects under contrasting high and low VPD conditions were investigated by integrated physiological and transcriptomic analyses.Beneficial CO_(2)fertilization effects were offset under high VPD conditions and were constrained by plant water stress and photosynthetic CO_(2)utilization.High VPD induced a large passive water driving force,which disrupted the water balance and consequently caused plant water deficit.Leaf water potential,turgor pressure,and hydraulic conductance declined under high VPD stress.The physiological evidence combined with transcriptomic analyses demonstrated that abscisic acid(ABA)and jasmonic acid(JA)potentially acted as drought-signaling molecules in response to high VPD stress.Increased foliar ABA and JA content triggered stomatal closure to prevent excessive water loss under high VPD stress,which simultaneously increased the diffusion resistance for CO_(2)uptake from atmosphere to leaf intercellular space.High VPD also significantly increased mesophyll resistance for CO_(2)transport from stomatal cavity to fixation site inside chloroplast.The chloroplast“sink”CO_(2)availability was constrained by stomatal and mesophyll resistance under high VPD stress,despite the atmospheric“source”CO_(2)concentration being elevated.Thus,ABA-and JA-mediated drought-resistant mechanisms potentially modified the beneficial effect of CO_(2)fertilization on photosynthesis,plant growth,and yield productivity.This study provides valuable information for improving the utilization efficiency of CO_(2)fertilization and a better understanding of the physiological processes. 展开更多
关键词 Abscisic acid CO_(2) fertilization Jasmonic acid Mesophyll conductance Stomatal conductance Vapor pressure deficit
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Flight Time Minimization of UAV for Cooperative Data Collection in Probabilistic LoS Channel
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作者 yan li Shaoyi Xu +1 位作者 Yunpu Wu Dongji li 《China Communications》 SCIE CSCD 2024年第2期210-226,共17页
This paper investigates the data collection in an unmanned aerial vehicle(UAV)-aided Internet of Things(IoT) network, where a UAV is dispatched to collect data from ground sensors in a practical and accurate probabili... This paper investigates the data collection in an unmanned aerial vehicle(UAV)-aided Internet of Things(IoT) network, where a UAV is dispatched to collect data from ground sensors in a practical and accurate probabilistic line-of-sight(LoS) channel. Especially, access points(APs) are introduced to collect data from some sensors in the unlicensed band to improve data collection efficiency. We formulate a mixed-integer non-convex optimization problem to minimize the UAV flight time by jointly designing the UAV 3D trajectory and sensors’ scheduling, while ensuring the required amount of data can be collected under the limited UAV energy. To solve this nonconvex problem, we recast the objective problem into a tractable form. Then, the problem is further divided into several sub-problems to solve iteratively, and the successive convex approximation(SCA) scheme is applied to solve each non-convex subproblem. Finally,the bisection search is adopted to speed up the searching for the minimum UAV flight time. Simulation results verify that the UAV flight time can be shortened by the proposed method effectively. 展开更多
关键词 data collection flight time probabilistic line-of-sight channel unlicensed band unmanned aerial vehicle
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Promise and challenges of traditional Chinese medicine,specifically Calculus bovis,in liver cancer treatment
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作者 Ao-Xi Xu Zhi-Feng Zhao +8 位作者 li Zhu Yi-Heng Zhang yan li Yu-Fan Wei Bo-Ya Zhang Bin Jiang Tian-Ze Gao Meng-Si li Jia-Yu liu 《World Journal of Gastroenterology》 SCIE CAS 2024年第40期4380-4385,共6页
Liver cancer,one of the most common malignancies worldwide,ranks sixth in incidence and third in mortality.Liver cancer treatment options are diverse,inclu-ding surgical resection,liver transplantation,percutaneous ab... Liver cancer,one of the most common malignancies worldwide,ranks sixth in incidence and third in mortality.Liver cancer treatment options are diverse,inclu-ding surgical resection,liver transplantation,percutaneous ablation,transarterial chemoembolization,radiotherapy,chemotherapy,targeted therapy,immuno-therapy,and traditional Chinese medicine(TCM).A multidisciplinary team(MDT)is essential to customize treatment plans based on tumor staging,liver function,and performance status(PS),ensuring individualized patient care.Treatment decisions require a MDT to tailor strategies based on tumor staging,liver function,and PS,ensuring personalized care.The approval of new first-line and second-line drugs and the establishment of standard treatments based on immune checkpoint inhibitors have significantly expanded treatment options for advanced liver cancer,improving overall prognosis.However,many patients do not respond effectively to these treatments and ultimately succumb to the disease.Modern oncology treatments,while extending patient survival,often come with severe side effects,resistance,and damage to the body,negatively impacting quality of life.Huang et al's study published at World Journal of Gastroenterology rigorously validates the anticancer properties of Calculus bovis,enhancing our understanding of TCM and contributing to new liver cancer treatment strategies.For over 5000 years,TCM has been used in East Asian countries like China to treat various diseases,including liver conditions.Analysis of real-world clinical data suggests that for patients with advanced-stage tumors lacking effective treatments,integrated TCM therapies could provide significant breakthroughs. 展开更多
关键词 Traditional Chinese medicine Liver cancer Calculus bovis TREATMENT PROMISE CHALLENGES
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Deep learning-assisted common temperature measurement based on visible light imaging
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作者 朱佳仪 何志民 +8 位作者 黄成 曾峻 林惠川 陈福昌 余超群 李燕 张永涛 陈焕庭 蒲继雄 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第8期230-236,共7页
Real-time,contact-free temperature monitoring of low to medium range(30℃-150℃)has been extensively used in industry and agriculture,which is usually realized by costly infrared temperature detection methods.This pap... Real-time,contact-free temperature monitoring of low to medium range(30℃-150℃)has been extensively used in industry and agriculture,which is usually realized by costly infrared temperature detection methods.This paper proposes an alternative approach of extracting temperature information in real time from the visible light images of the monitoring target using a convolutional neural network(CNN).A mean-square error of<1.119℃was reached in the temperature measurements of low to medium range using the CNN and the visible light images.Imaging angle and imaging distance do not affect the temperature detection using visible optical images by the CNN.Moreover,the CNN has a certain illuminance generalization ability capable of detection temperature information from the images which were collected under different illuminance and were not used for training.Compared to the conventional machine learning algorithms mentioned in the recent literatures,this real-time,contact-free temperature measurement approach that does not require any further image processing operations facilitates temperature monitoring applications in the industrial and civil fields. 展开更多
关键词 convolutional neural network visible light image temperature measurement low-to-medium-range temperatures
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TOEPLITZ OPERATORS BETWEEN WEIGHTED BERGMAN SPACES OVER THE HALF-PLANE
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作者 lixia FENG yan li +1 位作者 Zhiyu WANG liankuo ZHAO 《Acta Mathematica Scientia》 SCIE CSCD 2024年第5期1707-1720,共14页
In this paper,by characterizing Carleson measures,we investigate a class of bounded Toeplitz operator between weighted Bergman spaces with Békolléweights over the half-plane for all index choices.
关键词 weighted Bergman spaces Békolléweights Carleson measure Toeplitz operators
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Effects of Fe solid solute on grain boundaries of bi-crystal Cu: A molecular dynamics simulation
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作者 Shuohan yang Hongwei Bao +3 位作者 Huizhong Bai yan li Haodong Xu Fei Ma 《Nano Materials Science》 EI CAS CSCD 2024年第1期86-95,共10页
Grain boundaries(GBs)play a crucial role on the structural stability and mechanical properties of Cu and its alloys.In this work,molecular dynamics(MD)simulations are employed to study the effects of Fe solutes on the... Grain boundaries(GBs)play a crucial role on the structural stability and mechanical properties of Cu and its alloys.In this work,molecular dynamics(MD)simulations are employed to study the effects of Fe solutes on the formation energy,excess volume,dislocations and melting behaviors of GBs in CuFe alloys.It is illustrated that Fe solute affects the structural stability of Cu GBs substantially,the formation energy of GBs is reduced,but the thickness and melting point of GBs are increased,that is,the structural stability of Cu GBs is significantly improved owing to the Fe solutes.A strong scaling law exists between the formation energy,excess volume,thickness and melting point of GBs.Therefore,Fe solid solute plays an important role in the characteristics of GBs in bi-crystal Cu. 展开更多
关键词 CuFe alloy Grain boundary Structural stability MD simulations
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circPVT1 promotes silica-induced epithelial-mesenchymal transition by modulating the miR-497-5p/TCF3 axis
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作者 Siyun Zhou yan li +5 位作者 Wenqing Sun Dongyu Ma Yi liu Demin Cheng Guanru li Chunhui Ni 《Journal of Biomedical Research》 CAS CSCD 2024年第2期163-174,I0011-I0015,共17页
Epithelial-mesenchymal transition(EMT)is a vital pathological feature of silica-induced pulmonary fibrosis.However,whether circRNA is involved in the process remains unclear.The present study aimed to investigate the ... Epithelial-mesenchymal transition(EMT)is a vital pathological feature of silica-induced pulmonary fibrosis.However,whether circRNA is involved in the process remains unclear.The present study aimed to investigate the role of circPVT1 in the silica-induced EMT and the underlying mechanisms.We found that an elevated expression of circPVT1 promoted EMT and enhanced the migratory capacity of silica-treated epithelial cells.The isolation of cytoplasmic and nuclear separation assay showed that circPVT1 was predominantly expressed in the cytoplasm.RNA immunoprecipitation assay and RNA pull-down experiment indicated that cytoplasmic-localized circPVT1 was capable of binding to miR-497-5p.Furthermore,we found that miR-497-5p attenuated the silica-induced EMT process by targeting transcription factor 3(TCF3),an E-cadherin transcriptional repressor,in the silica-treated epithelial cells.Collectively,these results reveal a novel role of the circPVT1/miR-497-5p/TCF3 axis in the silica-induced EMT process in lung epithelial cells.Once validated,this finding may provide a potential theoretical basis for the development of interventions and treatments for pulmonary fibrosis. 展开更多
关键词 SILICOSIS epithelial-mesenchymal transition circPVT1 miR-497-5p TCF3
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Policy Gradient Adaptive Dynamic Programming for Model-Free Multi-Objective Optimal Control
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作者 Hao Zhang yan li +2 位作者 Zhuping Wang Yi Ding Huaicheng yan 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第4期1060-1062,共3页
Dear Editor,In this letter,the multi-objective optimal control problem of nonlinear discrete-time systems is investigated.A data-driven policy gradient algorithm is proposed in which the action-state value function is... Dear Editor,In this letter,the multi-objective optimal control problem of nonlinear discrete-time systems is investigated.A data-driven policy gradient algorithm is proposed in which the action-state value function is used to evaluate the policy.In the policy improvement process,the policy gradient based method is employed. 展开更多
关键词 POLICY GRADIENT OPTIMAL
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Aerodynamic Analysis and Optimization of Pantograph Streamline Fairing for High-Speed Trains
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作者 Xiang Kan yan li +1 位作者 Tian li Jiye Zhang 《Fluid Dynamics & Materials Processing》 EI 2024年第5期1075-1091,共17页
A pantograph serves as a vital device for the collection of electricity in trains.However,its aerodynamic resistance can limit the train’s running speed.As installing fairings around the pantograph is known to effect... A pantograph serves as a vital device for the collection of electricity in trains.However,its aerodynamic resistance can limit the train’s running speed.As installing fairings around the pantograph is known to effectively reduce the resistance,in this study,different fairing lengths are considered and the related aerodynamic performances of pantograph are assessed.In particular,this is accomplished through numerical simulations based on the k-ωShear Stress Transport(SST)two-equation turbulence model.The results indicate that the fairing diminishes the direct impact of high-speed airflow on the pantograph,thereby reducing its aerodynamic resistance.However,it also induces interferences in the flow field around the train,leading to variations in the aerodynamic resistance and lift of train components.It is shown that a maximum reduction of 56.52%in pantograph aerodynamic resistance and a peak decrease of 3.38%in total train aerodynamic resistance can be achieved. 展开更多
关键词 PANTOGRAPH FAIRING train aerodynamic numerical simulation
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Dietary cooking oils and cardiometabolic measurements in an elderly Chinese population
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作者 Xin-Yu WANG Chao-Ying MIAO +5 位作者 Xiao-Fei YE Wen-Yuan-Yue WANG Jia-Bo ZHU Yi ZHOU yan li Ji-Guang WANG 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2024年第6期642-650,共9页
OBJECTIVE To investigate three features of dietary cooking oil intake,namely,the consumption,cooking style,and composition of fatty acids in relation to several cardiometabolic measurements in an elderly Chinese popul... OBJECTIVE To investigate three features of dietary cooking oil intake,namely,the consumption,cooking style,and composition of fatty acids in relation to several cardiometabolic measurements in an elderly Chinese population.METHODS The elderly(≥65 years)participants for this study were recruited from two community health centers in the urban area of Shanghai.A questionnaire was administered to collect information on dietary oil consumption(low,medium and high)and cooking styles(fry or stir-fry vs.others)and the composition of fatty acids(poly-unsaturated vs.mono-unsaturated).The cardiometabolic measurements included anthropometry,blood pressure,fasting plasma glucose and serum lipids.RESULTS The 1186 study participants had a mean age of 70.9±5.4 years.The mean dietary oil consumption was 35.0 g/d,being low(<25 g/d),medium(25-49 g/d)and high(≥50 g/d)in 485,467 and 234 participants,respectively.The proportion of the fry or stir-fry cooking style and oils rich in mono-unsaturated fatty acids was 30.4%and 27.4%,respectively.Both before and after adjustment for sex,age,current smoking and alcohol intake,dietary oil consumption was significantly(P≤0.02)and positively associated with the prevalence of treated hypertension and fasting plasma glucose concentration.With similar adjustments as above and additional adjustment for dietary oil consumption,the fry or stir-fry cooking style was significantly(P≤0.048)and positively associated with body mass index,but inversely with systolic and diastolic blood pressure and serum low-density lipoprotein cholesterol,and the dietary intake of oils rich in mono-unsaturated fat acids was significantly(P≤0.02)and positively associated with diastolic blood pressure,serum triglycerides,total cholesterol and low-density lipoprotein cholesterol,and the prevalence of hypertriglyceridemia and hypercholesterolemia.CONCLUSIONS This study showed that both the consumption and composition of fatty acids of the dietary oils mattered with regard to several cardiometabolic measurements in an elderly Chinese population. 展开更多
关键词 COOKING ELDERLY UNSATURATED
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