Six novel thiosemicarbazones containing sugar and thiosemicarbazide moieties were synthesized by a five-step procedure using D-galactose and D-xylose as the starting materials and the corresponding glycosyl isothiocya...Six novel thiosemicarbazones containing sugar and thiosemicarbazide moieties were synthesized by a five-step procedure using D-galactose and D-xylose as the starting materials and the corresponding glycosyl isothiocyanates as the intermediates. The target compounds were characterized by IR, ^1H NMR, and elemental analysis. The coupliug constants between H1 and H2 in the sugar rings, all fail within the range of J = 9. 2-10.0 Hz, confirming the β-configuration of the compounds.展开更多
基金Supported by the Program for New Century Excellent Talents in University(No. NCET-04-04649)the National Natural Sci-ence Foundation of China(No 20475030)the Start-up Fund for Doctoral Scientific Research of Qingdao University of Science andTechnology.
文摘Six novel thiosemicarbazones containing sugar and thiosemicarbazide moieties were synthesized by a five-step procedure using D-galactose and D-xylose as the starting materials and the corresponding glycosyl isothiocyanates as the intermediates. The target compounds were characterized by IR, ^1H NMR, and elemental analysis. The coupliug constants between H1 and H2 in the sugar rings, all fail within the range of J = 9. 2-10.0 Hz, confirming the β-configuration of the compounds.
