目的探讨四脑室-蛛网膜下腔分流术(FVSS)治疗复发性、特发性脊髓空洞症(SM)的临床疗效。方法选择2019年1月至2021年6月郑州大学附属郑州中心医院收治的16例复发性、特发性SM患者为研究对象。所有患者均行FVSS,通过查阅病历资料收集患者...目的探讨四脑室-蛛网膜下腔分流术(FVSS)治疗复发性、特发性脊髓空洞症(SM)的临床疗效。方法选择2019年1月至2021年6月郑州大学附属郑州中心医院收治的16例复发性、特发性SM患者为研究对象。所有患者均行FVSS,通过查阅病历资料收集患者手术前后的症状资料。分别于术前1周及术后6个月应用改良日本骨科学会(mJOA)评分评估患者的神经功能。分别于术前1周及术后6个月,采用全脊髓磁共振成像检查患者脊髓空洞直径,相位对比磁共振成像(PC-MRI)测量中脑导水管中段、枕骨大孔收缩期及舒张期脑脊液流速,PC-MRI测量收缩期脑干背侧脑脊液循环情况,Queckensted试验检测患者40、60 mm Hg压力下的脑脊液峰值压力以及达峰时间;于术后6个月,采用芝加哥Chiari畸形预后量表(CCOS)评估患者预后情况。结果术前SM患者出现疼痛14例、节段性感觉分离10例、肢体麻木9例、上肢肌力下降9例、下肢肌力下降5例。术后13例患者疼痛明显改善,1例疼痛无明显改善。手术前后SM患者mJOA评分分别为5~11(9.86±2.20)、10~15(12.67±3.95)分,SM患者术后mJOA评分显著高于术前(P<0.05)。SM患者术后脊髓空洞直径显著低于术前(P<0.05)。SM患者术后收缩期和舒张期枕骨大孔脑脊液流速峰值、中脑导水管脑脊液流速峰值均显著低于术前(P<0.05);PC-MRI显示,与术前相比较,患者术后收缩期脑干背侧脑脊液循环信号更强。SM患者术后40、60 mm Hg压力下脑脊液压力峰值均显著高于术前(P<0.05);SM患者术后40、60 mm Hg压力下脑脊液压力达峰时间与术前比较差异无统计学意义(P>0.05)。SM患者预后良好14例,预后不良2例,患者均未出现神经损伤、脑脊液漏、感染等并发症。术后6个月复查PC-MRI及Queckensted试验显示,SM患者四脑室-蛛网膜下腔置入分流管固定良好,未发现分流管脱落及堵塞情况。结论FVSS可有效改善复发性、特发性SM患者的临床症状,改善神经功能和脑脊液循环情况,且预后良好。展开更多
Eight representative beach profiles on the eastern coast of the Shandong Peninsula are observed and measured in 2011 and 2012 to determine the coastal processes under the lower tropical wind speed condition and the be...Eight representative beach profiles on the eastern coast of the Shandong Peninsula are observed and measured in 2011 and 2012 to determine the coastal processes under the lower tropical wind speed condition and the beach response to and recovery from the tropical storm Meari in a rare typhoon region. The results show that it is the enhancement and directional change of cross-shore and longshore sediment transports caused by Meari that leads to the beach morphological changes, and most of the sediment transports occur during the pre-Meari landing phase. The erosional scarp formation and the berm or beach face erosion are the main geomorphological responses of the beaches to the storm. The storm characteristics are more important than the beach shapes in the storm response process of the beaches on Shandong Peninsula. The typhoon is a fortuitous strong dynamic event, and the effect on the dissipative beach is more obvious than it is on the reflective beach in the study region. Furthermore, the beach trend is the main factor that controlls the storm effect intensity, and it is also closely related to the recovery of the beach profiles.展开更多
In general,sediments in nature comprise populations of various diameters.Accurate information regarding the sources and depositional mechanisms of the populations can be obtained through their temporal and spatial com...In general,sediments in nature comprise populations of various diameters.Accurate information regarding the sources and depositional mechanisms of the populations can be obtained through their temporal and spatial comparisons.In this study,the grain size distribution of surface sediments from the Bering Sea and western Arctic Ocean were fitted and partitioned into populations using a log-normal distribution function.The spatial variations in the populations indicate differences in their sources and deposition mechanisms.The sediments on most of the Bering Sea Shelf originated from the Yukon River,and were transported westward by waves and currents.However,the presence of a coarser population outside Anadyr Bay was the result of Anadyr River transport.Additionally,a northward transport trend of fine suspended particles was observed on the west side of the Bering Sea Shelf.The sediments in Hope Valley in the south Chukchi Sea also originated from the Yukon River.The coarser population on the central Chukchi Sea Shelf originated from coast of Alaska to the east,not the Yukon River,and was transported by sea ice and bottom brine water.The populations of sediments from the Chukchi Basin and the base of the Chukchi Sea Slope are the result of sea ice and eddy action.Surface sediments from the western high Arctic Ocean predominantly comprised five populations,and two unique populations with mode diameters of 50–90μm and 200–400μm,respectively,were ubiquitous in the glacial and interglacial sediments.It was difficult to distinguish whether these two populations originated from sea ice or icebergs.Therefore,caution should be exercised when using either the>63μm or>250μm fractions in sediments as a proxy index for iceberg and ice sheet variation in the high Arctic Ocean.展开更多
文摘目的探讨四脑室-蛛网膜下腔分流术(FVSS)治疗复发性、特发性脊髓空洞症(SM)的临床疗效。方法选择2019年1月至2021年6月郑州大学附属郑州中心医院收治的16例复发性、特发性SM患者为研究对象。所有患者均行FVSS,通过查阅病历资料收集患者手术前后的症状资料。分别于术前1周及术后6个月应用改良日本骨科学会(mJOA)评分评估患者的神经功能。分别于术前1周及术后6个月,采用全脊髓磁共振成像检查患者脊髓空洞直径,相位对比磁共振成像(PC-MRI)测量中脑导水管中段、枕骨大孔收缩期及舒张期脑脊液流速,PC-MRI测量收缩期脑干背侧脑脊液循环情况,Queckensted试验检测患者40、60 mm Hg压力下的脑脊液峰值压力以及达峰时间;于术后6个月,采用芝加哥Chiari畸形预后量表(CCOS)评估患者预后情况。结果术前SM患者出现疼痛14例、节段性感觉分离10例、肢体麻木9例、上肢肌力下降9例、下肢肌力下降5例。术后13例患者疼痛明显改善,1例疼痛无明显改善。手术前后SM患者mJOA评分分别为5~11(9.86±2.20)、10~15(12.67±3.95)分,SM患者术后mJOA评分显著高于术前(P<0.05)。SM患者术后脊髓空洞直径显著低于术前(P<0.05)。SM患者术后收缩期和舒张期枕骨大孔脑脊液流速峰值、中脑导水管脑脊液流速峰值均显著低于术前(P<0.05);PC-MRI显示,与术前相比较,患者术后收缩期脑干背侧脑脊液循环信号更强。SM患者术后40、60 mm Hg压力下脑脊液压力峰值均显著高于术前(P<0.05);SM患者术后40、60 mm Hg压力下脑脊液压力达峰时间与术前比较差异无统计学意义(P>0.05)。SM患者预后良好14例,预后不良2例,患者均未出现神经损伤、脑脊液漏、感染等并发症。术后6个月复查PC-MRI及Queckensted试验显示,SM患者四脑室-蛛网膜下腔置入分流管固定良好,未发现分流管脱落及堵塞情况。结论FVSS可有效改善复发性、特发性SM患者的临床症状,改善神经功能和脑脊液循环情况,且预后良好。
基金The National Natural Science Foundation of China under contract No.41030856the Marine Specific Welfare Project of China under contract No.200905008-4the Project of Taishan Scholar
文摘Eight representative beach profiles on the eastern coast of the Shandong Peninsula are observed and measured in 2011 and 2012 to determine the coastal processes under the lower tropical wind speed condition and the beach response to and recovery from the tropical storm Meari in a rare typhoon region. The results show that it is the enhancement and directional change of cross-shore and longshore sediment transports caused by Meari that leads to the beach morphological changes, and most of the sediment transports occur during the pre-Meari landing phase. The erosional scarp formation and the berm or beach face erosion are the main geomorphological responses of the beaches to the storm. The storm characteristics are more important than the beach shapes in the storm response process of the beaches on Shandong Peninsula. The typhoon is a fortuitous strong dynamic event, and the effect on the dissipative beach is more obvious than it is on the reflective beach in the study region. Furthermore, the beach trend is the main factor that controlls the storm effect intensity, and it is also closely related to the recovery of the beach profiles.
基金financially supported by the scientific research foundation of Third Institute of Oceanography,MNR(Grant no.2018006)Chinese Polar Environment Comprehensive Investigation&Assessment Programmes(Grant no.2016-03-02)the National Natural Science Foundation of China(Grant nos.41306205,41876229)。
文摘In general,sediments in nature comprise populations of various diameters.Accurate information regarding the sources and depositional mechanisms of the populations can be obtained through their temporal and spatial comparisons.In this study,the grain size distribution of surface sediments from the Bering Sea and western Arctic Ocean were fitted and partitioned into populations using a log-normal distribution function.The spatial variations in the populations indicate differences in their sources and deposition mechanisms.The sediments on most of the Bering Sea Shelf originated from the Yukon River,and were transported westward by waves and currents.However,the presence of a coarser population outside Anadyr Bay was the result of Anadyr River transport.Additionally,a northward transport trend of fine suspended particles was observed on the west side of the Bering Sea Shelf.The sediments in Hope Valley in the south Chukchi Sea also originated from the Yukon River.The coarser population on the central Chukchi Sea Shelf originated from coast of Alaska to the east,not the Yukon River,and was transported by sea ice and bottom brine water.The populations of sediments from the Chukchi Basin and the base of the Chukchi Sea Slope are the result of sea ice and eddy action.Surface sediments from the western high Arctic Ocean predominantly comprised five populations,and two unique populations with mode diameters of 50–90μm and 200–400μm,respectively,were ubiquitous in the glacial and interglacial sediments.It was difficult to distinguish whether these two populations originated from sea ice or icebergs.Therefore,caution should be exercised when using either the>63μm or>250μm fractions in sediments as a proxy index for iceberg and ice sheet variation in the high Arctic Ocean.
