2017年3月3-4日,中国临床肿瘤学会(Chinese Society of Clinical Oncology,CSCO)和中国抗癌协会肺癌专业委员会联合主办了第十四届“中国肺癌高峰论坛”。本次论坛的主题是“精准与联合:共谱免疫治疗新乐章”。检查点抑制剂(Check...2017年3月3-4日,中国临床肿瘤学会(Chinese Society of Clinical Oncology,CSCO)和中国抗癌协会肺癌专业委员会联合主办了第十四届“中国肺癌高峰论坛”。本次论坛的主题是“精准与联合:共谱免疫治疗新乐章”。检查点抑制剂(Checkpoint inhibitor)因其对多肿瘤类别广泛的适用性及能带来持久的有效缓解,短期内在全球范围掀起了免疫治疗的狂潮。而在非小细胞肺癌患者中,免疫治疗同样带来了令人欣喜的临床获益。展开更多
This paper examines major active faults and the present-day tectonic stress field in the East Tibetan Plateau by integrating available data from published literature and proposes a block kinematics model of the region...This paper examines major active faults and the present-day tectonic stress field in the East Tibetan Plateau by integrating available data from published literature and proposes a block kinematics model of the region. It shows that the East Tibetan Plateau is dominated by strike-slip and reverse faulting stress regimes and that the maximum horizontal stress is roughly consistent with the contemporary velocity field, except for the west Qinling range where it parallels the striking of the major strike-slip faults. Active tectonics in the East Tibetan Plateau is characterized by three faulting systems. The left-slip Kunlun-Qinling faulting system combines the east Kunlun fault zone, sinistral oblique reverse faults along the Minshan range and two major NEE-striking faults cutting the west Qinling range, which accommodates eastward motion, at 10--14 mm/a, of the Chuan-Qing block. The left-slip Xianshuihe faulting system accommodated clockwise rotation of the Chuan-Dian block. The Longmenshan thrust faulting system forms the eastern margin of the East Tibetan Plateau and has been propagated to the SW of the Sichuan basin. Crustal shortening across the Longmenshan range seems low (2-4 mm/a) and absorbed only a small part of the eastward motion of the Chuan-Qing block. Most of this eastward motion has been transmitted to South China, which is moving SEE-ward at 7-9 mm/a. It is suggested from geophysical data interpretation that the crust and lithosphere of the East Tibetan Plateau is considerably thickened and theologically layered. The upper crust seems to be decoupled from the lower crust through a decollement zone at a depth of 15-20 kin, which involved the Longmenshan fault belt and propagated eastward to the SW of the Sichuan basin. The Wenchuan earthquake was just formed at the bifurcated point of this decollement system. A rheological boundary should exist beneath the Longmenshan fault belt where the lower crust of the East Tibetan Plateau and the lithospheric mantle of the Yangze block are juxtaposed.展开更多
The rapid identification based on InSAR technology was proved to be effective in our emergency investigation of surface ruptures and geohazards induced by the Yushu earthquake.The earthquake-generating fault of the Yu...The rapid identification based on InSAR technology was proved to be effective in our emergency investigation of surface ruptures and geohazards induced by the Yushu earthquake.The earthquake-generating fault of the Yushu earthquake is the Yushu section of the Garze-Yushu faults zone.It strikes NWW-NW,23 km long near the Yushu County seat,dominated by left-lateral strike slip,and appearing as a surface rupture zone.The macroscopic epicenter is positioned at Guo-yang-yan -song-duo of Gyegu Town(33°03'11"N,96°51'26"E),where the co-seismic horizontal offset measured is 1.75 m.Geohazards induced by the Yushu earthquake are mainly rockfalls,landslides,debris flows, and unstable slopes.They are controlled by the earthquake-generating fault and are mostly distributed along it.There are several geohazard chains having been established,such as earthquake,canal damage,soil liquefying,landslide-debris flow,earthquake,soil liquefying,roadbed deformation,etc.In order to prevent seismic hazards,generally,where there is a visible surface rupture induced by the Yushu earthquake,reconstruction should be at least beyond 20 m,on each side,from it.Sufficient attention should also be given to potential geohazards or geohazard chains induced by the earthquake.展开更多
A three-dimensional local-scale P-velocity model down to 25 km depth around the main shock epicenter region was constructed using 83821 event-to-receiver seismic rays from 5856 aftershocks recorded by a newly deployed...A three-dimensional local-scale P-velocity model down to 25 km depth around the main shock epicenter region was constructed using 83821 event-to-receiver seismic rays from 5856 aftershocks recorded by a newly deployed temporary seismic network. Checkerboard tests show that our tomographic model has lateral and vertical resolution of -2 km. The high-resolution P-velocity model revealed interesting structures in the seismogenic layer: (1) The Guanxian-Anxian fault, Yingxiu-Beichuan fault and Wenchuan-Maoxian fault of the Longmen Shan fault zone are well delineated by sharp upper crustal velocity changes; (2) The Pengguan massif has generally higher velocity than its surrounding areas, and may extend down to at least -10 km from the surface; (3) A sharp lateral velocity variation beneath the Wenchuan-Maoxian fault may indicate that the Pengguan massif's western boundary and/or the Wenchuan-Maoxian fault is vertical, and the hypocenter of the Wenchuan earthquake possibly located at the conjunction point of the NW dipping Yingxiu-Beichuan and Guanxian-Anxian faults, and vertical Wenchuan-Maoxian fault; (4) Vicinity along the Yingxiu- Beichuan fault is characterized by very low velocity and low seismicity at shallow depths, possibly due to high content of porosity and fractures; (5) Two blocks of low-velocity anomaly are respectively imaged in the hanging wall and foot wall of the Guanxian-Anxian fault with a -7 km offset with -5 km vertical component.展开更多
文摘2017年3月3-4日,中国临床肿瘤学会(Chinese Society of Clinical Oncology,CSCO)和中国抗癌协会肺癌专业委员会联合主办了第十四届“中国肺癌高峰论坛”。本次论坛的主题是“精准与联合:共谱免疫治疗新乐章”。检查点抑制剂(Checkpoint inhibitor)因其对多肿瘤类别广泛的适用性及能带来持久的有效缓解,短期内在全球范围掀起了免疫治疗的狂潮。而在非小细胞肺癌患者中,免疫治疗同样带来了令人欣喜的临床获益。
基金the auspice of National Key Basic Project(973)(granted number 2008CB425702)National Science and Technology Project(granted Number SinoProbe-08)China Geological Survey project(granted number1212010670104)
文摘This paper examines major active faults and the present-day tectonic stress field in the East Tibetan Plateau by integrating available data from published literature and proposes a block kinematics model of the region. It shows that the East Tibetan Plateau is dominated by strike-slip and reverse faulting stress regimes and that the maximum horizontal stress is roughly consistent with the contemporary velocity field, except for the west Qinling range where it parallels the striking of the major strike-slip faults. Active tectonics in the East Tibetan Plateau is characterized by three faulting systems. The left-slip Kunlun-Qinling faulting system combines the east Kunlun fault zone, sinistral oblique reverse faults along the Minshan range and two major NEE-striking faults cutting the west Qinling range, which accommodates eastward motion, at 10--14 mm/a, of the Chuan-Qing block. The left-slip Xianshuihe faulting system accommodated clockwise rotation of the Chuan-Dian block. The Longmenshan thrust faulting system forms the eastern margin of the East Tibetan Plateau and has been propagated to the SW of the Sichuan basin. Crustal shortening across the Longmenshan range seems low (2-4 mm/a) and absorbed only a small part of the eastward motion of the Chuan-Qing block. Most of this eastward motion has been transmitted to South China, which is moving SEE-ward at 7-9 mm/a. It is suggested from geophysical data interpretation that the crust and lithosphere of the East Tibetan Plateau is considerably thickened and theologically layered. The upper crust seems to be decoupled from the lower crust through a decollement zone at a depth of 15-20 kin, which involved the Longmenshan fault belt and propagated eastward to the SW of the Sichuan basin. The Wenchuan earthquake was just formed at the bifurcated point of this decollement system. A rheological boundary should exist beneath the Longmenshan fault belt where the lower crust of the East Tibetan Plateau and the lithospheric mantle of the Yangze block are juxtaposed.
基金supported by the National Natural Science Foundation of China(grant No.40902059)the Land Resource Survey Project of China Geological Survey (grant No.1212010914025,No.1212011014035)the Fundamental Research Fund of Institute of Geomechanics, CAGS(grant No.DZLXJK200906)
文摘The rapid identification based on InSAR technology was proved to be effective in our emergency investigation of surface ruptures and geohazards induced by the Yushu earthquake.The earthquake-generating fault of the Yushu earthquake is the Yushu section of the Garze-Yushu faults zone.It strikes NWW-NW,23 km long near the Yushu County seat,dominated by left-lateral strike slip,and appearing as a surface rupture zone.The macroscopic epicenter is positioned at Guo-yang-yan -song-duo of Gyegu Town(33°03'11"N,96°51'26"E),where the co-seismic horizontal offset measured is 1.75 m.Geohazards induced by the Yushu earthquake are mainly rockfalls,landslides,debris flows, and unstable slopes.They are controlled by the earthquake-generating fault and are mostly distributed along it.There are several geohazard chains having been established,such as earthquake,canal damage,soil liquefying,landslide-debris flow,earthquake,soil liquefying,roadbed deformation,etc.In order to prevent seismic hazards,generally,where there is a visible surface rupture induced by the Yushu earthquake,reconstruction should be at least beyond 20 m,on each side,from it.Sufficient attention should also be given to potential geohazards or geohazard chains induced by the earthquake.
基金the Basic Research Foundation of the Institute of Geomechanics,CAGS(grant DZLXJK200707)Natural Science Foundation of China grant 40674058)
文摘A three-dimensional local-scale P-velocity model down to 25 km depth around the main shock epicenter region was constructed using 83821 event-to-receiver seismic rays from 5856 aftershocks recorded by a newly deployed temporary seismic network. Checkerboard tests show that our tomographic model has lateral and vertical resolution of -2 km. The high-resolution P-velocity model revealed interesting structures in the seismogenic layer: (1) The Guanxian-Anxian fault, Yingxiu-Beichuan fault and Wenchuan-Maoxian fault of the Longmen Shan fault zone are well delineated by sharp upper crustal velocity changes; (2) The Pengguan massif has generally higher velocity than its surrounding areas, and may extend down to at least -10 km from the surface; (3) A sharp lateral velocity variation beneath the Wenchuan-Maoxian fault may indicate that the Pengguan massif's western boundary and/or the Wenchuan-Maoxian fault is vertical, and the hypocenter of the Wenchuan earthquake possibly located at the conjunction point of the NW dipping Yingxiu-Beichuan and Guanxian-Anxian faults, and vertical Wenchuan-Maoxian fault; (4) Vicinity along the Yingxiu- Beichuan fault is characterized by very low velocity and low seismicity at shallow depths, possibly due to high content of porosity and fractures; (5) Two blocks of low-velocity anomaly are respectively imaged in the hanging wall and foot wall of the Guanxian-Anxian fault with a -7 km offset with -5 km vertical component.