Selective laser melting(SLM)has been applied to manufacture various alloy components with excellent properties,but its further application is restricted by the intrinsic defects.In this work,the internal defect distri...Selective laser melting(SLM)has been applied to manufacture various alloy components with excellent properties,but its further application is restricted by the intrinsic defects.In this work,the internal defect distributions in samples of three alloys(316L stainless steel,AlSi10Mg and Inconel 718)were investigated respectively,considering the effects of geometrical characteristics of the samples.The defects in the 316L stainless steel sample tend to be formed densely in the central part with large wall thickness,indicating a strong sensitivity to heat accumulation.Contrarily,the Inconel 718 sample shows a higher relative density with homogeneous defect distribution,indicating better formability for the SLM process.For the AlSi10Mg sample,the defect density keeps increasing as the deposition goes on.Typically,the defect density located at sample edges shows an abnormally high level comparing with the inner part,especially in the top sections of AlSi10Mg and Inconel 718 samples.The results are helpful for the geometrical design,the adjustment of building orientation and the further optimization of process parameters in the SLM process.展开更多
Background:Remnant microhabitats are important for bird habitat selection and plant regeneration in the fragmented habitat.However,empirical information on the consequences of how microhabitat use by birds affects the...Background:Remnant microhabitats are important for bird habitat selection and plant regeneration in the fragmented habitat.However,empirical information on the consequences of how microhabitat use by birds affects the early recruitment of plants is lacking.Methods:In this study,we evaluated whether microhabitat selection by the Black Bulbul(Hypsipetes leucocephalus)(J.F.Gmelin,1789)impacts the early recruitment of the endangered tree species,the Chinese Yew(Taxus chinensis(Pilger)Rehd),in a fragmented forest over a 4-year period(2011–2012,2018–2019).Results:Our results showed the main factors affecting H.leucocephalus microhabitat selection were distance to the nearest T.chinensis mature tree,herb cover and density,leaf litter cover,and vegetation type.Moreover,the results of logistic regression also highlighted the importance of elevation,distance to light gap and roads,tree cover in bird microhabitat selection.Furthermore,the seed emergence rate in microhabitats used by birds did not differ from the natural forest,which was related to five factors of bird microhabitat.The Random Forest model showed that seedling emergence rate was increased with leaf litter cover and distance to fallen dead trees,but decreased in relation to herb cover,slope,and elevation.Conclusion:Our results highlight the importance of remnant microhabitats in fragmented forests for sustaining forest ecology and optimal management.The contribution of microhabitats used by birds to plant recruitment provides insights into how frugivore species contribute to plant regeneration,which should be incorporated in future conservation and management practices of fragmented forests.展开更多
Thrust tests of a linear synchronous motor(LSM)with its secondary made of coated superconducting coils were conducted via the built prototype over the traditional copper windings.A numerical model of the superconducti...Thrust tests of a linear synchronous motor(LSM)with its secondary made of coated superconducting coils were conducted via the built prototype over the traditional copper windings.A numerical model of the superconducting LSM was made and the measured data of experiment validate its reliability.The nonlinear resistivity of coated superconductor was electromagnetically modeled by resorting to the power law in conjunction with the constitutive relationship of conductor.Based on the numerical model,we carried out a set of transient studies to make a forecast about the superiority of the proposed high temperature superconducting(HTS)LSM,such as magnetic field distribution and the time evolution of thrust together with the speed in different loads and frequencies.The achieved results clearly confirm that the proposed HTS LSM has the advantages to work as a candidate for developing the high-thrust LSM with a large air gap.展开更多
Nanocomposite Cr C/hydrogenated amorphous carbon(nc-CrC/a-C:H) coatings were deposited by a hybrid beams system comprised of a hollow cathode ion source and a cathodic arc ion-plating unit with varying H_2 flow rates....Nanocomposite Cr C/hydrogenated amorphous carbon(nc-CrC/a-C:H) coatings were deposited by a hybrid beams system comprised of a hollow cathode ion source and a cathodic arc ion-plating unit with varying H_2 flow rates. The influences of H_2 flow rates on the morphologies, microstructures, and properties of the coatings were systematically studied. The morphologies and microstructures of the coatings were characterized by SEM, AFM, XPS, Raman spectroscopy, GIXRD, and HRTEM. The mechanical and tribological properties were measured by a nano-indenter, scratch tester, and ball-ondisk tribometer. The wear tracks were evaluated using 3D profilometer, optical microscope, and EDS analysis. It has been found that a moderate H_2 flow rate can effectively smooth the surface, enlarge the fraction of a sp^3 bond, and improve the properties. The coating exhibits the highest hardness and elastic modulus at the H_2 flow rate of 40 sccm. A superior combination of adhesion strength,friction coefficient, and wear resistance can be achieved at the H_2 flow rate of 80 sccm.展开更多
Protein-protein interactions are vital for a wide range of biological processes.The interactions between the hypoxia-inducible factor and von Hippel Lindau(VHL)are attractive drug targets for ischemic heart disease.In...Protein-protein interactions are vital for a wide range of biological processes.The interactions between the hypoxia-inducible factor and von Hippel Lindau(VHL)are attractive drug targets for ischemic heart disease.In order to disrupt this interaction,the strategy to target VHL binding site using a hydroxyproline-like(pro-like)small molecule has been reported.In this study,we focused on the inhibition mechanism between the pro-like inhibitors and the VHL protein,which were investigated via molecular dynamics simulations and binding free energy calculations.It was found that pro-like inhibitors showed a strong binding affinity toward VHL.Binding free energy calculations and free energy decompositions suggested that the modification of various regions of pro-like inhibitors may provide useful information for future drug design.展开更多
Reptiles are the most morphologically and physiologically diverse tetrapods,with the squamates having the most diverse habitats.Lizard is an important model system for understanding the role of visual ecology,phylogen...Reptiles are the most morphologically and physiologically diverse tetrapods,with the squamates having the most diverse habitats.Lizard is an important model system for understanding the role of visual ecology,phylogeny and behavior on the structure of visual systems.In this study,we compared three opsin genes(RH2,LWS and SWS1)among 49 reptile species to detect positively selected genes as well as amino acid sites.Our results indicated that visual opsin genes have undergone divergent selection pressures in all lizards and RH2 and LWS suffered stronger positive selection than SWS1.Twelve positively selected sites were picked out for RH2 and LWS.Moreover,many diagnostic sites were found between geckos and non-gecko lizards,most of which were located near the positively selected sites and some of them have already been reported to be responsible for significant shifts of the wavelength of maximum absorption(λ_(max)).The results indicated that the gecko lineage accelerated the evolution of these genes to adapt to the dim-light environment or nocturnality as well as the switch between nocturnality and diurnality.展开更多
The differences in the climatology of extratropical transition(ET) of western North Pacific tropical cyclones(TCs) were investigated in this study using the TCs best-track datasets of China Meteorological Administrati...The differences in the climatology of extratropical transition(ET) of western North Pacific tropical cyclones(TCs) were investigated in this study using the TCs best-track datasets of China Meteorological Administration(CMA),Japan Meteorological Agency(JMA) and the Joint Typhoon Warning Center(JTWC). The results show that the ET identification, ET completion time, and post-ET duration reported in the JTWC dataset are greatly different from those in CMA and JMA datasets during 2004-2010. However, the key differences between the CMA and JMA datasets from 1951 to 2010 are the ET identification and the post-ET duration, because of inconsistent objective ET criteria used in the centers. Further analysis indicates that annual ET percentage of CMA was lower than that of JMA, and exhibited an interannual decreasing trend, while that of JMA was an unchanged trend. The western North Pacific ET events occurred mainly during the period June to November. The latitude of ET occurrence shifted northward from February to August,followed by a southward shift. Most of ET events were observed between 35°N and 45°N. From a regional perspective,TCs tended to undergo ET in Japan and the ocean east to it. It is found that TCs which experienced the ET process at higher latitudes were generally more intense at the ET completion time. TCs completing the ET overland or offshore were weaker than those finishing the ET over the ocean. Most of the TCs weakened 24 h before the completion of ET.In contrast, 21%(27%) of the TCs showed an intensification process based on the CMA(JMA) dataset during the post-ET period. The results presented in this study indicate that consistent ET determination criteria are needed to reduce the uncertainty involved in ET identification among the centers.展开更多
For modular multilevel converter-based battery energy storage systems (MMC-BESS), uneven power among batteries of SMs will be deduced by battery aging, battery fault, etc., which will degrade performance and even lead...For modular multilevel converter-based battery energy storage systems (MMC-BESS), uneven power among batteries of SMs will be deduced by battery aging, battery fault, etc., which will degrade performance and even lead to system failure. For maintaining the balance of capacitor voltage, this paper analyzes the limits of the uneven power of batteries, which are presented as the current limits in this paper. According to analysis, an analytical method is proposed that only the dc and fundamental frequency components of the arm current are used to calculate current limits. With the current limits it is able to evaluate the reasonability of power distribution among batteries. Meanwhile, increase of fundamental frequency component will enhance the current limits, and the dc component determines the size relationship between the absolute values of the upper and lower current limits. Finally, simulation model and experiment prototype are built for verifying the theoretical analysis and current limits calculation method, and satisfactory results are provided.展开更多
基金the National Key R&D Program of China(No.2018YFB1106100)Jiangsu Key Laboratory for Advanced Metallic Materials(No.BM2007204)。
文摘Selective laser melting(SLM)has been applied to manufacture various alloy components with excellent properties,but its further application is restricted by the intrinsic defects.In this work,the internal defect distributions in samples of three alloys(316L stainless steel,AlSi10Mg and Inconel 718)were investigated respectively,considering the effects of geometrical characteristics of the samples.The defects in the 316L stainless steel sample tend to be formed densely in the central part with large wall thickness,indicating a strong sensitivity to heat accumulation.Contrarily,the Inconel 718 sample shows a higher relative density with homogeneous defect distribution,indicating better formability for the SLM process.For the AlSi10Mg sample,the defect density keeps increasing as the deposition goes on.Typically,the defect density located at sample edges shows an abnormally high level comparing with the inner part,especially in the top sections of AlSi10Mg and Inconel 718 samples.The results are helpful for the geometrical design,the adjustment of building orientation and the further optimization of process parameters in the SLM process.
基金This study was supported by the National Natural Science Foundation of China(Grant No.31700468)the Natural Science Foundation of Jiangsu Province(Grant No.BK2017636).
文摘Background:Remnant microhabitats are important for bird habitat selection and plant regeneration in the fragmented habitat.However,empirical information on the consequences of how microhabitat use by birds affects the early recruitment of plants is lacking.Methods:In this study,we evaluated whether microhabitat selection by the Black Bulbul(Hypsipetes leucocephalus)(J.F.Gmelin,1789)impacts the early recruitment of the endangered tree species,the Chinese Yew(Taxus chinensis(Pilger)Rehd),in a fragmented forest over a 4-year period(2011–2012,2018–2019).Results:Our results showed the main factors affecting H.leucocephalus microhabitat selection were distance to the nearest T.chinensis mature tree,herb cover and density,leaf litter cover,and vegetation type.Moreover,the results of logistic regression also highlighted the importance of elevation,distance to light gap and roads,tree cover in bird microhabitat selection.Furthermore,the seed emergence rate in microhabitats used by birds did not differ from the natural forest,which was related to five factors of bird microhabitat.The Random Forest model showed that seedling emergence rate was increased with leaf litter cover and distance to fallen dead trees,but decreased in relation to herb cover,slope,and elevation.Conclusion:Our results highlight the importance of remnant microhabitats in fragmented forests for sustaining forest ecology and optimal management.The contribution of microhabitats used by birds to plant recruitment provides insights into how frugivore species contribute to plant regeneration,which should be incorporated in future conservation and management practices of fragmented forests.
基金This work was supported in part by the National Natural Science Foundation of China under Grants 51722706,in part by the Sichuan Youth Science&Technology Foundation under Grant 2016JQ0003,in part by the State Key Laboratory of Traction Power under Grant 2015TPL_T04.
文摘Thrust tests of a linear synchronous motor(LSM)with its secondary made of coated superconducting coils were conducted via the built prototype over the traditional copper windings.A numerical model of the superconducting LSM was made and the measured data of experiment validate its reliability.The nonlinear resistivity of coated superconductor was electromagnetically modeled by resorting to the power law in conjunction with the constitutive relationship of conductor.Based on the numerical model,we carried out a set of transient studies to make a forecast about the superiority of the proposed high temperature superconducting(HTS)LSM,such as magnetic field distribution and the time evolution of thrust together with the speed in different loads and frequencies.The achieved results clearly confirm that the proposed HTS LSM has the advantages to work as a candidate for developing the high-thrust LSM with a large air gap.
基金supported by the National Natural Science Foundation of China(Nos.11275141 and 11175133)the International Cooperation Program of the Ministry of Science and Technology of China(No.2015DFR00720)+2 种基金the Center for Electron Microscopy of Wuhan Universitythe Center of Nanosci. and Nanotech,Research of Wuhan Universitythe Analysis and Test Center of Wuhan University
文摘Nanocomposite Cr C/hydrogenated amorphous carbon(nc-CrC/a-C:H) coatings were deposited by a hybrid beams system comprised of a hollow cathode ion source and a cathodic arc ion-plating unit with varying H_2 flow rates. The influences of H_2 flow rates on the morphologies, microstructures, and properties of the coatings were systematically studied. The morphologies and microstructures of the coatings were characterized by SEM, AFM, XPS, Raman spectroscopy, GIXRD, and HRTEM. The mechanical and tribological properties were measured by a nano-indenter, scratch tester, and ball-ondisk tribometer. The wear tracks were evaluated using 3D profilometer, optical microscope, and EDS analysis. It has been found that a moderate H_2 flow rate can effectively smooth the surface, enlarge the fraction of a sp^3 bond, and improve the properties. The coating exhibits the highest hardness and elastic modulus at the H_2 flow rate of 40 sccm. A superior combination of adhesion strength,friction coefficient, and wear resistance can be achieved at the H_2 flow rate of 80 sccm.
基金supported by the National Natural Science Foundation of China(No.21973064)the Post-Doctor Research Project,West China Hospital,Sichuan University(No.2021HXBH017)。
文摘Protein-protein interactions are vital for a wide range of biological processes.The interactions between the hypoxia-inducible factor and von Hippel Lindau(VHL)are attractive drug targets for ischemic heart disease.In order to disrupt this interaction,the strategy to target VHL binding site using a hydroxyproline-like(pro-like)small molecule has been reported.In this study,we focused on the inhibition mechanism between the pro-like inhibitors and the VHL protein,which were investigated via molecular dynamics simulations and binding free energy calculations.It was found that pro-like inhibitors showed a strong binding affinity toward VHL.Binding free energy calculations and free energy decompositions suggested that the modification of various regions of pro-like inhibitors may provide useful information for future drug design.
基金Financial support was provided by the National Natural Science Foundation of China(NSFC)(Grant No.31672269,31000949 to J.YAN)the Natural Science Foundation of the Jiangsu Higher Education Institutions of China(19KJA330001 to P.LI)+1 种基金the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)Top-Notch Academic Programs Project of Jiangsu Higher Education Institutions(TAPP,PPZY2015B117)。
文摘Reptiles are the most morphologically and physiologically diverse tetrapods,with the squamates having the most diverse habitats.Lizard is an important model system for understanding the role of visual ecology,phylogeny and behavior on the structure of visual systems.In this study,we compared three opsin genes(RH2,LWS and SWS1)among 49 reptile species to detect positively selected genes as well as amino acid sites.Our results indicated that visual opsin genes have undergone divergent selection pressures in all lizards and RH2 and LWS suffered stronger positive selection than SWS1.Twelve positively selected sites were picked out for RH2 and LWS.Moreover,many diagnostic sites were found between geckos and non-gecko lizards,most of which were located near the positively selected sites and some of them have already been reported to be responsible for significant shifts of the wavelength of maximum absorption(λ_(max)).The results indicated that the gecko lineage accelerated the evolution of these genes to adapt to the dim-light environment or nocturnality as well as the switch between nocturnality and diurnality.
基金National Natural Science Foundation of China(41465003)National Natural Science Foundation of China(41665006)China National Special Funding Project for Meteorology(GYHY201406010,GYHY201306071)
文摘The differences in the climatology of extratropical transition(ET) of western North Pacific tropical cyclones(TCs) were investigated in this study using the TCs best-track datasets of China Meteorological Administration(CMA),Japan Meteorological Agency(JMA) and the Joint Typhoon Warning Center(JTWC). The results show that the ET identification, ET completion time, and post-ET duration reported in the JTWC dataset are greatly different from those in CMA and JMA datasets during 2004-2010. However, the key differences between the CMA and JMA datasets from 1951 to 2010 are the ET identification and the post-ET duration, because of inconsistent objective ET criteria used in the centers. Further analysis indicates that annual ET percentage of CMA was lower than that of JMA, and exhibited an interannual decreasing trend, while that of JMA was an unchanged trend. The western North Pacific ET events occurred mainly during the period June to November. The latitude of ET occurrence shifted northward from February to August,followed by a southward shift. Most of ET events were observed between 35°N and 45°N. From a regional perspective,TCs tended to undergo ET in Japan and the ocean east to it. It is found that TCs which experienced the ET process at higher latitudes were generally more intense at the ET completion time. TCs completing the ET overland or offshore were weaker than those finishing the ET over the ocean. Most of the TCs weakened 24 h before the completion of ET.In contrast, 21%(27%) of the TCs showed an intensification process based on the CMA(JMA) dataset during the post-ET period. The results presented in this study indicate that consistent ET determination criteria are needed to reduce the uncertainty involved in ET identification among the centers.
基金supported by Key Research and Development Program of Hebei Province under Grant 19214405DNational Natural Science Foundation of China under Grant 51677162.
文摘For modular multilevel converter-based battery energy storage systems (MMC-BESS), uneven power among batteries of SMs will be deduced by battery aging, battery fault, etc., which will degrade performance and even lead to system failure. For maintaining the balance of capacitor voltage, this paper analyzes the limits of the uneven power of batteries, which are presented as the current limits in this paper. According to analysis, an analytical method is proposed that only the dc and fundamental frequency components of the arm current are used to calculate current limits. With the current limits it is able to evaluate the reasonability of power distribution among batteries. Meanwhile, increase of fundamental frequency component will enhance the current limits, and the dc component determines the size relationship between the absolute values of the upper and lower current limits. Finally, simulation model and experiment prototype are built for verifying the theoretical analysis and current limits calculation method, and satisfactory results are provided.
