Urban renewal is one of the important contents of urban development in China. With the gradual progress of urbanization, the renewal of the old city has become the focus of urbanization. This paper analyzed the street...Urban renewal is one of the important contents of urban development in China. With the gradual progress of urbanization, the renewal of the old city has become the focus of urbanization. This paper analyzed the street space form in the old city, and explored the characteristics of the street space form with a view to exploring streets whose space forms are suitable for the current social development. Based on the field investigation of Shijia Hutong, the White Stupa Temple area, and Dashilanr, the similarities and differences of streets in these areas with different space forms in the old city of Beijing were compared and analyzed, and social and cultural factors expressed in urban space form and the impact of human activities on the street space form were explored in terms of the scale, function, building type, and connection with the outside world. It is hoped that this paper will provide a reference for future renovation of the Old City.展开更多
AIM： To analyze cytokines as biomarkers for evaluation of severity of glaucoma. METHODS： This was a prospective case-control study including 29 eyes with glaucoma. Besides, 28 eyes with senile cataract were used as...AIM： To analyze cytokines as biomarkers for evaluation of severity of glaucoma. METHODS： This was a prospective case-control study including 29 eyes with glaucoma. Besides, 28 eyes with senile cataract were used as control. Patients were classified into four groups： acute angle closure glaucoma （AACG）, chronic angle closure glaucoma （CACG）, primary open angle glaucoma （POAG） and senile cataract. Undiluted vitreous samples were collected, then vitreous concentrations of 9 types of cytokines were determined by cytometric bead assay system： y-interferon （IFNg）, interleukin （IL-10, IL-2, IL-4, IL-5, interferon-y-inducible protein （IP）-10, monocyte chemoattractant protein （MCP）-I, tumor necrosis factor （TNF） -Q, and vascular endothelial growth factor （VEGF）. We also recorded the intraocular pressure （lOP） of patients in each group and Pearson correlated analysis was performed to analysis the correlation between each type of cytokine with IOR RESULTS： Vitreous levels of IL-2, iL-5, MCP-1, TNF-a and IP-10 were significantly higher （P〈0.05） in AACG group. Patients with AACG, CACG and POAG have higher lOP than senile cataract, but we didn＇t find any significant correlation between lOP with any type of the cytokines. CONCLUSION： Inflammation and immune reaction have a strong link with the pathology of glaucoma especially AACG, Some cytokines may act as biomarkers to evaluate the severity of glaucoma, Anti-inflammatory treatments and controlling of lOP are necessary for the therapy of glaucoma.展开更多
基金Sponsored by Science and Technology Programs for Students in North China University of TechnologyService Capacity Building of Scientific and Technological Innovation-Raising the Quota Level of Scientific Research-Research Institute of Building Systems(PXM2017_014212_000005)
文摘Urban renewal is one of the important contents of urban development in China. With the gradual progress of urbanization, the renewal of the old city has become the focus of urbanization. This paper analyzed the street space form in the old city, and explored the characteristics of the street space form with a view to exploring streets whose space forms are suitable for the current social development. Based on the field investigation of Shijia Hutong, the White Stupa Temple area, and Dashilanr, the similarities and differences of streets in these areas with different space forms in the old city of Beijing were compared and analyzed, and social and cultural factors expressed in urban space form and the impact of human activities on the street space form were explored in terms of the scale, function, building type, and connection with the outside world. It is hoped that this paper will provide a reference for future renovation of the Old City.
基金Supported by the National Natural Science Fundation of China(No.81371040)Shanghai Pujiang Program(No.15PJD028)Scientific Research Project of Shanghai Municipal Health Bureau(No.20124149)
文摘AIM： To analyze cytokines as biomarkers for evaluation of severity of glaucoma. METHODS： This was a prospective case-control study including 29 eyes with glaucoma. Besides, 28 eyes with senile cataract were used as control. Patients were classified into four groups： acute angle closure glaucoma （AACG）, chronic angle closure glaucoma （CACG）, primary open angle glaucoma （POAG） and senile cataract. Undiluted vitreous samples were collected, then vitreous concentrations of 9 types of cytokines were determined by cytometric bead assay system： y-interferon （IFNg）, interleukin （IL-10, IL-2, IL-4, IL-5, interferon-y-inducible protein （IP）-10, monocyte chemoattractant protein （MCP）-I, tumor necrosis factor （TNF） -Q, and vascular endothelial growth factor （VEGF）. We also recorded the intraocular pressure （lOP） of patients in each group and Pearson correlated analysis was performed to analysis the correlation between each type of cytokine with IOR RESULTS： Vitreous levels of IL-2, iL-5, MCP-1, TNF-a and IP-10 were significantly higher （P〈0.05） in AACG group. Patients with AACG, CACG and POAG have higher lOP than senile cataract, but we didn＇t find any significant correlation between lOP with any type of the cytokines. CONCLUSION： Inflammation and immune reaction have a strong link with the pathology of glaucoma especially AACG, Some cytokines may act as biomarkers to evaluate the severity of glaucoma, Anti-inflammatory treatments and controlling of lOP are necessary for the therapy of glaucoma.
