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双波长激光联合曲安奈德注射对鸡冠血管的作用 被引量:1
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作者 李彦锋 魏芳 +4 位作者 周自广 马晓焕 勾爱丽 姚亚琼 陈文娇 《中国中西医结合皮肤性病学杂志》 CAS 2019年第2期120-122,共3页
目的研究585 nm/1 064 nm双波长激光联合曲安奈德注射对血管瘤动物模型鸡冠的作用,探讨联合应用治疗血管瘤的可行性。方法将莱亨鸡随机分为A、B、C共3组,每组10只,A组曲安奈德注射实验组,B组双波长激光实验组,C组联合应用实验组,以未处... 目的研究585 nm/1 064 nm双波长激光联合曲安奈德注射对血管瘤动物模型鸡冠的作用,探讨联合应用治疗血管瘤的可行性。方法将莱亨鸡随机分为A、B、C共3组,每组10只,A组曲安奈德注射实验组,B组双波长激光实验组,C组联合应用实验组,以未处理侧鸡冠作为自身对照。各组观察第1、3、7、14天实验动物一般情况及鸡冠大体变化,分别在第3、7、14天切取各组鸡冠组织块,观察组织学变化。实验结束后,计算毛细血管减少率,行统计学分析。结果 3组鸡冠均出现不同程度的褪色,组织学观察均可见毛细血管减少,A、B、C组的毛细血管减少率分别为(68.03 1.80)%、(70.01 2.21)%和(89.63 1.93)%。A、B组之间比较差异无统计学意义(t=1.39,P>0.05),C组与A组、C组与B组之间比较差异均有统计学意义(t=34.31,22.09;均P <0.05)。结论双波长激光联合曲安奈德注射能有效作用于鸡冠毛细血管,且效果优于单一疗法。 展开更多
关键词 血管瘤 激光疗法 曲安奈德
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Optimal Poisson Subsampling for Softmax Regression 被引量:1
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作者 yao yaqiong ZOU Jiahui WANG Haiying 《Journal of Systems Science & Complexity》 SCIE EI CSCD 2023年第4期1609-1625,共17页
Softmax regression,which is also called multinomial logistic regression,is widely used in various fields for modeling the relationship between covariates and categorical responses with multiple levels.The increasing v... Softmax regression,which is also called multinomial logistic regression,is widely used in various fields for modeling the relationship between covariates and categorical responses with multiple levels.The increasing volumes of data bring new challenges for parameter estimation in softmax regression,and the optimal subsampling method is an effective way to solve them.However,optimal subsampling with replacement requires to access all the sampling probabilities simultaneously to draw a subsample,and the resultant subsample could contain duplicate observations.In this paper,the authors consider Poisson subsampling for its higher estimation accuracy and applicability in the scenario that the data exceed the memory limit.The authors derive the asymptotic properties of the general Poisson subsampling estimator and obtain optimal subsampling probabilities by minimizing the asymptotic variance-covariance matrix under both A-and L-optimality criteria.The optimal subsampling probabilities contain unknown quantities from the full dataset,so the authors suggest an approximately optimal Poisson subsampling algorithm which contains two sampling steps,with the first step as a pilot phase.The authors demonstrate the performance of our optimal Poisson subsampling algorithm through numerical simulations and real data examples. 展开更多
关键词 Multinomial logistic regression optimality criterion optimal subsampling
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