Synthesis, Crystal Structure and Biological Evaluation of 6'-Chloro-4'-methylene-3H-spiro[isobenzofuran-1,3'-isochroman]

The title compound 6?-chloro-4?-methylene-3 H-spiro [isoben zofura-1,3?-isochroman], C_(17)H_(13)ClO_2, was prepared and characterized by IR, NMR, HRMS and single-crystal X-ray diffraction. This compound has a bisbenzannulated [5,5]-spiroketals skeleton. It crystallizes in orthorhombic, space group P212121 with a = 13.383(3), b = 7.6120(17), c = 13.793(3) ?, Z = 4, Dc= 1.275 g/cm^3, μ = 0.28 mm^(–1), F(000) = 592, wR = 0.1443 and R = 0.0557. The preliminary biological test showed that the title compound has good anti-bacterial activities in vitro.

大学城建设对地方城市化进程的推动作用——以宜春市教体新区大学城为例

建设大学城是地方发挥高等教育集聚效应的优先发展模式,也是加快区域城市化进程,促进地方经济增长的一条有效途径。宜春市教体新区大学城建设不仅能提高宜春市中心城区的城市化率,而且可以推动宜春市产业结构的转换升级,发展新型服务业,促进文体、旅游业,美化城市形象,提高城市竞争力,有利于区域性中心城市的建成。