期刊文献+
共找到3篇文章
< 1 >
每页显示 20 50 100
鼠李糖乳杆菌GG对大鼠脂多糖应激下抗氧化能力、免疫功能和肠道健康的影响
1
作者 尹龙杰 张雨 +5 位作者 陈舒焕 谷梦影 李洒洒 甄东恒 张薇 张立阳 《饲料工业》 CAS 北大核心 2024年第9期93-100,共8页
试验旨在探究鼠李糖乳杆菌GG(Lactobacillus rhamnosus GG,LGG)对SD大鼠生长性能及脂多糖(LPS)应激条件下抗氧化能力、免疫功能和肠道健康的影响。选取24只体重、日龄相近的健康雄性SD大鼠,前期随机分为对照组(CON组)和LGG组,每组6个重... 试验旨在探究鼠李糖乳杆菌GG(Lactobacillus rhamnosus GG,LGG)对SD大鼠生长性能及脂多糖(LPS)应激条件下抗氧化能力、免疫功能和肠道健康的影响。选取24只体重、日龄相近的健康雄性SD大鼠,前期随机分为对照组(CON组)和LGG组,每组6个重复,每个重复2只。LGG组大鼠每日灌胃1×10^(8) CFU/mL LGG 2 mL,CON组灌胃等量生理盐水,连续灌胃15 d。试验第14天,分别从CON组和LGG组每个重复中随机挑选1只大鼠,按体重腹腔注射2 mg/kg LPS溶液,分别命名为LPS组和LGG+LPS组,剩余大鼠注射等量无菌生理盐水。大鼠麻醉后解剖,采集血清、回肠,检测抗氧化指标、炎症因子水平以及回肠形态。结果表明:与CON组相比,LGG组料重比有降低趋势(0.05≤P<0.10);LPS应激导致大鼠血清中谷丙转氨酶(ALT)、谷草转氨酶(AST)、免疫球蛋白A(IgA)、免疫球蛋白G(IgG)、免疫球蛋白M(IgM)、白细胞介素1β(IL-1β)、白细胞介素6(IL-6)、白细胞介素8(IL-8)、肿瘤坏死因子α(TNF-α)含量显著升高(P<0.05),总蛋白(TP)和白蛋白(ALB)含量显著下降(P<0.05),而在LPS应激下LGG预处理可显著降低血清中ALT、AST、IgA、IgG、IgM、IL-1β、IL-8和TNF-α含量(P<0.05),显著提高ALB和TP含量(P<0.05);此外,LPS应激还导致血清和回肠黏膜过氧化氢酶(CAT)含量和总抗氧化能力(T-AOC)显著下降(P<0.05),丙二醛(MDA)含量显著上升(P<0.05);在LPS应激下LGG预处理可显著提高血清和回肠黏膜CAT含量及回肠黏膜T-AOC(P<0.05),显著降低血清和回肠黏膜MDA含量(P<0.05);各组间大鼠肝脏、胸腺和脾脏指数以及回肠绒毛高度、绒毛宽度、隐窝深度和绒毛高度/隐窝深度均无显著差异(P>0.05)。综上所述,LPS应激诱导大鼠肝脏损伤、氧化应激及免疫应激,LGG预处理可在一定程度提高大鼠饲料转化率,通过提高机体本身抗氧化功能、免疫功能预防和缓解LPS应激产生的负面作用。 展开更多
关键词 鼠李糖乳杆菌GG 大鼠 生长性能 抗氧化能力 免疫功能
下载PDF
Vision-based Stabilization of Nonholonomic Mobile Robots by Integrating Sliding-mode Control and Adaptive Approach 被引量:4
2
作者 CAO Zhengcai yin longjie FU Yili 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2013年第1期21-28,共8页
Vision-based pose stabilization of nonholonomic mobile robots has received extensive attention. At present, most of the solutions of the problem do not take the robot dynamics into account in the controller design, so... Vision-based pose stabilization of nonholonomic mobile robots has received extensive attention. At present, most of the solutions of the problem do not take the robot dynamics into account in the controller design, so that these controllers are difficult to realize satisfactory control in practical application. Besides, many of the approaches suffer from the initial speed and torque jump which are not practical in the real world. Considering the kinematics and dynamics, a two-stage visual controller for solving the stabilization problem of a mobile robot is presented, applying the integration of adaptive control, sliding-mode control, and neural dynamics. In the first stage, an adaptive kinematic stabilization controller utilized to generate the command of velocity is developed based on Lyapunov theory. In the second stage, adopting the sliding-mode control approach, a dynamic controller with a variable speed function used to reduce the chattering is designed, which is utilized to generate the command of torque to make the actual velocity of the mobile robot asymptotically reach the desired velocity. Furthermore, to handle the speed and torque jump problems, the neural dynamics model is integrated into the above mentioned controllers. The stability of the proposed control system is analyzed by using Lyapunov theory. Finally, the simulation of the control law is implemented in perturbed case, and the results show that the control scheme can solve the stabilization problem effectively. The proposed control law can solve the speed and torque jump problems, overcome external disturbances, and provide a new solution for the vision-based stabilization of the mobile robot. 展开更多
关键词 nonholonomic mobile robots vision-based stabilization sliding-mode control adaptive control neural dynamics
下载PDF
数据伦理视角下档案用户数据隐私保护研究 被引量:13
3
作者 张东华 尹泷杰 卢俊 《档案学研究》 CSSCI 北大核心 2022年第2期97-101,共5页
随着数据的广泛运用和影响的普及化,数据隐私保护逐渐成为社会关注的焦点。文章着眼于数据伦理的视角,从数据利益、数据技术、数据鸿沟、数据立法四个方面出发,分析当前我国档案用户数据隐私保护伦理失范问题,并提出深化数据伦理道德教... 随着数据的广泛运用和影响的普及化,数据隐私保护逐渐成为社会关注的焦点。文章着眼于数据伦理的视角,从数据利益、数据技术、数据鸿沟、数据立法四个方面出发,分析当前我国档案用户数据隐私保护伦理失范问题,并提出深化数据伦理道德教育、创新数据伦理技术管理、健全数据伦理约束机制、完善数据伦理法律法规等实施路径。 展开更多
关键词 数据伦理 档案用户 数据隐私 隐私保护
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部