High Physical Activity is Associated with an Improved Lipid Profile and Resting Heart Rate among Healthy Middle-aged Chinese People

Objective To investigate the effects of physical activity （PA） on dyslipidemia and elevated resting heart rate （RHR） in a large-scale cross-sectional study in China. Methods We recruited community-based individuals who were 40-60 years old using a cluster sampling method. The PA levels of the participants were classified as low, moderate, or high, using the International Physical Activity Questionnaire. Dyslipidemia was defined as the detection of abnormalities in lipid indicators, and 4 lipid parameters were evaluated using fasting blood samples. Multivariate logistic regression analyses were used to evaluate the associations of PA with dyslipidemia and RHR. Results A total of 10,321 participants （38.88% men） were included in this study. The percentages of individuals with high, moderate, and low PA levels were 46.5%, 43.9%, and 9.6%, respectively. In both men and women, high PA provided odds ratios of 0.88 [95% confidence interval （CI）： 0.83, 0.94] for dyslipidemia and 0.82 （95% CI： 0.73, 0.92） for elevated RHR, compared to participants with low PA. Conclusion Our data suggested that substantial health benefits （related to dyslipidemia and elevated RHR） occurred at higher intensity PA, with greater energy consumption, in middle-aged Chinese people, and particularly in men.

Association between Physical Activity and Higher Serum Creatinine/Uric Acid by Dose-response Association

Serum creatinine （Scr） and serum uric acid （sUA）arecloselyrelatedchronicdiseaseorassociated morbidity.Epidemiologicalevidenceshowsthat elevated Scr or higher sUA level are independent risk factors for cardiovascular disease as well as gout and insulin resistance[1].Physicalactivity（PA）isgenerallyconsidered importantinregulatinghealth.