Background It is unclear whether a history of paroxysmal atrial fibrillation （PAF） would impact the effect of catheter ablation on persistent atrial fibrillation （AF）. This study aimed to compare the effect of cat...Background It is unclear whether a history of paroxysmal atrial fibrillation （PAF） would impact the effect of catheter ablation on persistent atrial fibrillation （AF）. This study aimed to compare the effect of catheter ablation on persistent AF with and without a history of PAF. Methods One hundred and eighty-three patients underwent catheter ablation of persistent AF lasting for 〉1 month and were reviewed. Patients were divided into two groups according to whether they had a history of PAF or not. Group I consisted of persistent AF patients with a history of PAF, and group II consisted of persistent AF patients without such a history. All patients received catheter ablation focused on pulmonary vein isolation and were observed for arrhythmia recurrences, which were defined as documented episodes of AF or atrial tachycardia after a blanking period of 3 months. Results One hundred and three patients （60.9%） in group I and sixty-six patients （39.1%） in group II were successfully followed and included in analysis. There were no significant differences in clinical and echocardiographic characteristics between both groups except for a younger age and more male patients in group II. After （15.5±10.7） months of follow-up, 59 （57.3%） patients in group I and 49 （74.2%） patients in group II maintained sinus rhythm free of anti-arrhythmia drugs （P=0.025）. Multivariate analyses found left atrial anteroposterior diameter （P=0.006） and persistent AF with a history of PAF （OR 1.792, 95% CI 1.019-3.152; P=0.043） as the only independent statistical predictors of arrhythmia recurrences. Conclusion The arrhythmia recurrence rate of catheter ablation based on pulmonary vein isolation in persistent AF with a history of PAF was hiQher than those without a history of PAF展开更多
目的探究在左房扩大的心房颤动(AF)患者中,左房前壁基质改变对窦性心律下12导联心电图V1导联P波终末电势(PTFV1)和心房激动时间(AAT)的影响。方法入选行经导管心内膜消融术且心房扩大的AF患者98例[73.5%为阵发性AF]。将患者分为3组:前...目的探究在左房扩大的心房颤动(AF)患者中,左房前壁基质改变对窦性心律下12导联心电图V1导联P波终末电势(PTFV1)和心房激动时间(AAT)的影响。方法入选行经导管心内膜消融术且心房扩大的AF患者98例[73.5%为阵发性AF]。将患者分为3组:前壁线性消融组(20例),前壁低电压组(21例)和对照组(57例)。记录所有患者术后的常规12导联心电图,比较各组之间PTFV1和AAT。结果前壁线性消融组较对照组PTFV1减小,AAT延迟[PTFV1:(0.007±0.011)mm·s vs (0.034±0.038)mm·s,P=0.024;AAT:(152.8±40.9)ms vs(91.6±21.1)ms,P<0.001];前壁低电压组患者较对照组的PTFV1亦减小,AAT亦延迟[PTFV1:(0.008±0.014)mm·s vs (0.034±0.038)mm·s,P=0.048;AAT:(137.7±40.8)ms vs (91.6±21.1)ms,P<0.001]。前壁线性消融组和前壁低电压组的PTFV1和AAT差别无显著性。结论左房扩大的患者, PTFV1减小,AAT延长提示左房前壁基质异常。展开更多
文摘Background It is unclear whether a history of paroxysmal atrial fibrillation （PAF） would impact the effect of catheter ablation on persistent atrial fibrillation （AF）. This study aimed to compare the effect of catheter ablation on persistent AF with and without a history of PAF. Methods One hundred and eighty-three patients underwent catheter ablation of persistent AF lasting for 〉1 month and were reviewed. Patients were divided into two groups according to whether they had a history of PAF or not. Group I consisted of persistent AF patients with a history of PAF, and group II consisted of persistent AF patients without such a history. All patients received catheter ablation focused on pulmonary vein isolation and were observed for arrhythmia recurrences, which were defined as documented episodes of AF or atrial tachycardia after a blanking period of 3 months. Results One hundred and three patients （60.9%） in group I and sixty-six patients （39.1%） in group II were successfully followed and included in analysis. There were no significant differences in clinical and echocardiographic characteristics between both groups except for a younger age and more male patients in group II. After （15.5±10.7） months of follow-up, 59 （57.3%） patients in group I and 49 （74.2%） patients in group II maintained sinus rhythm free of anti-arrhythmia drugs （P=0.025）. Multivariate analyses found left atrial anteroposterior diameter （P=0.006） and persistent AF with a history of PAF （OR 1.792, 95% CI 1.019-3.152; P=0.043） as the only independent statistical predictors of arrhythmia recurrences. Conclusion The arrhythmia recurrence rate of catheter ablation based on pulmonary vein isolation in persistent AF with a history of PAF was hiQher than those without a history of PAF
文摘目的探究在左房扩大的心房颤动(AF)患者中,左房前壁基质改变对窦性心律下12导联心电图V1导联P波终末电势(PTFV1)和心房激动时间(AAT)的影响。方法入选行经导管心内膜消融术且心房扩大的AF患者98例[73.5%为阵发性AF]。将患者分为3组:前壁线性消融组(20例),前壁低电压组(21例)和对照组(57例)。记录所有患者术后的常规12导联心电图,比较各组之间PTFV1和AAT。结果前壁线性消融组较对照组PTFV1减小,AAT延迟[PTFV1:(0.007±0.011)mm·s vs (0.034±0.038)mm·s,P=0.024;AAT:(152.8±40.9)ms vs(91.6±21.1)ms,P<0.001];前壁低电压组患者较对照组的PTFV1亦减小,AAT亦延迟[PTFV1:(0.008±0.014)mm·s vs (0.034±0.038)mm·s,P=0.048;AAT:(137.7±40.8)ms vs (91.6±21.1)ms,P<0.001]。前壁线性消融组和前壁低电压组的PTFV1和AAT差别无显著性。结论左房扩大的患者, PTFV1减小,AAT延长提示左房前壁基质异常。
