目的:评价针刺治疗原发性抑郁症系统评价的方法学质量、报告质量以及结论的可靠程度。方法:计算机检索Web of science、Embase、PubMed、Cochrane library、中国知网、中国生物医学文献数据库、万方数据库、维普数据库获取公开发表的针...目的:评价针刺治疗原发性抑郁症系统评价的方法学质量、报告质量以及结论的可靠程度。方法:计算机检索Web of science、Embase、PubMed、Cochrane library、中国知网、中国生物医学文献数据库、万方数据库、维普数据库获取公开发表的针刺治疗原发性抑郁症的系统评价/Meta分析,检索时间限制为建库至2018年12月5日。由两名研究者独立筛选文献并提取资料,运用AMSTAR工具评价纳入研究的方法学质量,PRISMA工具评价报告质量,GRADE系统对结局指标重新进行证据质量分级。结果:最终纳入18篇系统评价/Meta分析,均以针刺干预为主,包含2个主要结局指标。根据AMSTAR,有4个高质量研究,12个中等质量研究和2个低质量研究。根据PRISMA清单,所有报告主要的问题在于均没有研究方案的注册以及对所提取的数据条目、具体检索策略和是否有资助来源等描述不足。GRADE评级显示,2项结局指标为中级,6个为低级,其余均为极低质量。结论:针刺治疗原发性抑郁症的疗效是明确的,但尚不能评价不同针刺干预方法之间的优劣,期待更多的系统评价以更好地综合最新证据全面比较不同针刺方法的优劣。展开更多
对三阴交穴的敏化现象进行总结与归纳,以期为今后研究穴位敏化的规律提供理论依据。选用中国生物医学文献数据库(CBM)、中国期刊全文数据库(CNKI)、万方数据库(WF)、维普数据库(VIP)、PubMed、Embase、Cochrane Library、Web of Science...对三阴交穴的敏化现象进行总结与归纳,以期为今后研究穴位敏化的规律提供理论依据。选用中国生物医学文献数据库(CBM)、中国期刊全文数据库(CNKI)、万方数据库(WF)、维普数据库(VIP)、PubMed、Embase、Cochrane Library、Web of Science(WOS)等8个数据库进行检索,收集三阴交穴的相关敏化文献,同时建立三阴交穴的现代敏化文献数据库,对敏化类型、疾病种类以及检测方法等有关信息进行总结与分析。最终符合标准的文献有48篇,敏化类型涉及热敏、痛敏、电敏、力敏、声敏以及形敏,其中以热敏现象报道最多。三阴交穴发生敏化的疾病类型以妇科疾病多见。各敏化现象检测方式多样,热敏多借助温和灸探寻及红外热成像仪方式;痛敏多采用疼痛测量仪、甩尾反应、扭体反应等;电敏多选用皮肤导电量测试仪、穴位伏安特性检测仪以及腧穴探测仪等;力敏检测主要选用穴位诊查法;声敏主要声波声波发射和接收系统;形敏则通过穴位的外部观察。在疾病状态下,三阴交穴敏化出现率高,穴位的皮肤形态、温度、痛阈、电阻及按压等均出现异常反应,温度和电阻甚至会出现左右失衡现象。展开更多
Objective To evaluate the quality of the existing studies and summarize evidence of important outcomes of meta-analyses/systematic reviews(MAs/SRs)of CFS.Methods Potentially eligible studies were searched in the follo...Objective To evaluate the quality of the existing studies and summarize evidence of important outcomes of meta-analyses/systematic reviews(MAs/SRs)of CFS.Methods Potentially eligible studies were searched in the following electronic databases from inception to 1 September,2019:Chinese Biomedical Literature Database(CBM),China Science and Technology Journal Database(VIP),China National Knowledge Infrastructure(CNKI),WanFang Database(WF),Web of Science,Embase,PubMed and Cochrane Library.Grades of Recommendation,Assessment,Development,and Evaluation(GRADE)was used to evaluate the quality of evidence.The methodological quality of the literature was evaluated by A Measure Tool to Assess Systematic Reviews-2(AMSTAR-2)and the quality of the report was assessed by Preferred Reporting Items for Systematic Reviews and Meta-analyses(PRISMA).The intra-class correlation coefficient was used to assess the consistency of the reviewers,with an overall intraclass correlation coefficient score of 0.967.Results Ten MAs/SRs were included.The overall conclusions were that acupuncture had good safety and efficacy in the treatment of CFS,but some of these results were contradictory.The GRADE indicated that out of the 17 outcomes,high-quality evidence was provided in 0(0%),moderate in 3(17.65%),low in 10(58.82%),and very low in 4(23.53%).The results of AMSTAR-2 showed that the methodological quality of all included studies was critically low.The PRISMA statement revealed that 8 articles(80%)were in line with 20 of the 27-item checklist,and 2 articles(20%)matched with 10-19 of the 27 items.Conclusion We found that acupuncture on treating CFS has the advantage for efficacy and safety,but the quality of SRs/MAs of acupuncture for CFS need to be improved.展开更多
文摘目的:评价针刺治疗原发性抑郁症系统评价的方法学质量、报告质量以及结论的可靠程度。方法:计算机检索Web of science、Embase、PubMed、Cochrane library、中国知网、中国生物医学文献数据库、万方数据库、维普数据库获取公开发表的针刺治疗原发性抑郁症的系统评价/Meta分析,检索时间限制为建库至2018年12月5日。由两名研究者独立筛选文献并提取资料,运用AMSTAR工具评价纳入研究的方法学质量,PRISMA工具评价报告质量,GRADE系统对结局指标重新进行证据质量分级。结果:最终纳入18篇系统评价/Meta分析,均以针刺干预为主,包含2个主要结局指标。根据AMSTAR,有4个高质量研究,12个中等质量研究和2个低质量研究。根据PRISMA清单,所有报告主要的问题在于均没有研究方案的注册以及对所提取的数据条目、具体检索策略和是否有资助来源等描述不足。GRADE评级显示,2项结局指标为中级,6个为低级,其余均为极低质量。结论:针刺治疗原发性抑郁症的疗效是明确的,但尚不能评价不同针刺干预方法之间的优劣,期待更多的系统评价以更好地综合最新证据全面比较不同针刺方法的优劣。
文摘对三阴交穴的敏化现象进行总结与归纳,以期为今后研究穴位敏化的规律提供理论依据。选用中国生物医学文献数据库(CBM)、中国期刊全文数据库(CNKI)、万方数据库(WF)、维普数据库(VIP)、PubMed、Embase、Cochrane Library、Web of Science(WOS)等8个数据库进行检索,收集三阴交穴的相关敏化文献,同时建立三阴交穴的现代敏化文献数据库,对敏化类型、疾病种类以及检测方法等有关信息进行总结与分析。最终符合标准的文献有48篇,敏化类型涉及热敏、痛敏、电敏、力敏、声敏以及形敏,其中以热敏现象报道最多。三阴交穴发生敏化的疾病类型以妇科疾病多见。各敏化现象检测方式多样,热敏多借助温和灸探寻及红外热成像仪方式;痛敏多采用疼痛测量仪、甩尾反应、扭体反应等;电敏多选用皮肤导电量测试仪、穴位伏安特性检测仪以及腧穴探测仪等;力敏检测主要选用穴位诊查法;声敏主要声波声波发射和接收系统;形敏则通过穴位的外部观察。在疾病状态下,三阴交穴敏化出现率高,穴位的皮肤形态、温度、痛阈、电阻及按压等均出现异常反应,温度和电阻甚至会出现左右失衡现象。
基金the National Natural Science Foundation of China(No.81590951 and No.81722050)。
文摘Objective To evaluate the quality of the existing studies and summarize evidence of important outcomes of meta-analyses/systematic reviews(MAs/SRs)of CFS.Methods Potentially eligible studies were searched in the following electronic databases from inception to 1 September,2019:Chinese Biomedical Literature Database(CBM),China Science and Technology Journal Database(VIP),China National Knowledge Infrastructure(CNKI),WanFang Database(WF),Web of Science,Embase,PubMed and Cochrane Library.Grades of Recommendation,Assessment,Development,and Evaluation(GRADE)was used to evaluate the quality of evidence.The methodological quality of the literature was evaluated by A Measure Tool to Assess Systematic Reviews-2(AMSTAR-2)and the quality of the report was assessed by Preferred Reporting Items for Systematic Reviews and Meta-analyses(PRISMA).The intra-class correlation coefficient was used to assess the consistency of the reviewers,with an overall intraclass correlation coefficient score of 0.967.Results Ten MAs/SRs were included.The overall conclusions were that acupuncture had good safety and efficacy in the treatment of CFS,but some of these results were contradictory.The GRADE indicated that out of the 17 outcomes,high-quality evidence was provided in 0(0%),moderate in 3(17.65%),low in 10(58.82%),and very low in 4(23.53%).The results of AMSTAR-2 showed that the methodological quality of all included studies was critically low.The PRISMA statement revealed that 8 articles(80%)were in line with 20 of the 27-item checklist,and 2 articles(20%)matched with 10-19 of the 27 items.Conclusion We found that acupuncture on treating CFS has the advantage for efficacy and safety,but the quality of SRs/MAs of acupuncture for CFS need to be improved.
