斜基粗叶木化学成分研究

目的:研究斜基粗叶木Lasianthus wallichii(Wight et Arn.)Wight的化学成分。方法:采用柱色谱方法进行分离纯化,通过理化性质及波谱学方法鉴定化合物结构。结果:从斜基粗叶木中分离得到12个化合物,分别鉴定为:虎刺醇-3-O-β-D-樱草糖苷(1)、虎刺醇-11-甲醚(2)、长尾粗叶木素A(3)、长尾粗叶木苷A(4)、芦西丁-3-O-β-D-樱草糖苷(5)、甲基异茜草素(6)、东莨菪素(7)、虎刺醇(8)、damnacanthol-11-O-β-glucoside(9)、lucidin dimethyl ether(10)、胡萝卜苷(11)、β-谷甾醇(12)。结论:其中,化合物1~10为首次从该植物中分离得到。

白鹤藤的化学成分研究

目的:研究白鹤藤Argyreia aceta Lour.的化学成分。方法:采用硅胶、大孔吸附树脂、ODS柱、Sephadex LH-20葡聚糖凝胶、制备液相等色谱方法对其化学成分进行分离,并根据理化性质及波谱数据鉴定化合物结构。结果:从白鹤藤中分离得到12个化合物,分别鉴定为:东莨菪苷(1)、薯蓣次苷B(2)、diosgenyl-3-O-α-L-rhamnopyranosyl(1→3)-α-L-rhamnopyranosyl(1→4)-β-D-glucoside(3)、6′-O-acetylscopolin(4)、东莨菪内酯(5)、山柰酚-4′,7-二甲醚(6)、鼠李秦素(7)、鼠李柠檬素(8)、商陆黄素(9)、异槲皮苷(10)、山柰酚-3-O-β-D-吡喃葡萄糖苷(11)、银锻苷(12)。结论:其中,化合物2~12为首次从该植物中分离得到。

Three resin glycosides isolated from Argyreia acuta, including two isomers

In the present study, three compounds were isolated from Argyreia acuta, among them, compounds 1 and 2 were new and Compounds 1 and 3 were isomers. They were separated by several types of columns, such as normal phase, RP, size exclusion and preparative HPLC, and their structures were elucidated by several spectroscopic methods, such as 1D-and 2D-NMR and HR-TOF-MS.