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培菲康在ICU危重病患者胃肠功能紊乱中的作用分析
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作者 于红娟 张巍 《中国实用医药》 2023年第5期35-38,共4页
目的探讨双歧杆菌三联活菌(商品名:培菲康)在重症加强护理病房(ICU)危重病患者胃肠功能紊乱中的作用。方法60例ICU危重病胃肠功能紊乱患者,随机分为实验组与对照组,各30例。对照组患者采取常规肠内营养制剂治疗,实验组在对照组基础上增... 目的探讨双歧杆菌三联活菌(商品名:培菲康)在重症加强护理病房(ICU)危重病患者胃肠功能紊乱中的作用。方法60例ICU危重病胃肠功能紊乱患者,随机分为实验组与对照组,各30例。对照组患者采取常规肠内营养制剂治疗,实验组在对照组基础上增加培菲康治疗。比较两组治疗前后的胃肠功能评分、急性生理功能和慢性健康状况量表(APACHEⅡ)评分,Marshall评分,多器官功能障碍综合征(MODS)发生率、存活率,治疗前后胃肠道症状评分。结果治疗后,实验组胃肠功能评分(0.35±0.12)分低于对照组的(0.95±0.27)分,差异有统计学意义(P<0.05)。治疗后,实验组APACHEⅡ评分(15.68±5.12)分低于对照组的(19.32±5.27)分,差异有统计学意义(P<0.05)。治疗后,实验组Marshall评分(4.36±2.12)分低于对照组的(6.58±2.27)分,差异有统计学意义(P<0.05)。实验组MODS发生率13.33%低于对照组的40.00%,差异有统计学意义(P<0.05)。实验组存活率90.00%高于对照组的56.67%,差异有统计学意义(P<0.05)。治疗后,实验组腹胀、腹泻、便秘评分分别为(0.69±0.25)、(0.62±0.97)、(0.85±0.18)分,均低于对照组的(1.24±0.98)、(1.63±0.78)、(2.41±0.32)分,差异有统计学意义(P<0.05)。结论针对ICU危重病胃肠功能紊乱患者,通过采用培菲康加常规肠内营养制剂进行治疗,患者的腹胀、腹泻和便秘症状得到显著改善,故此种治疗方法具备比较好的临床推广意义。 展开更多
关键词 双歧杆菌三联活菌 重症加强护理病房危重病 胃肠功能紊乱
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医学免疫学“课程思政”的教学改革与探索 被引量:129
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作者 马兴铭 张李峰 +6 位作者 王竞秋 雒艳萍 吴玉凤 谭继英 梁亚玲 于红娟 曹明强 《医学教育研究与实践》 2018年第6期1013-1015,1086,共4页
"课程思政"是加强高等学校大学生思想政治教育的重要途径,为更好地发挥"课程思政"的协同育人效应,基于医学免疫学的课程特点,把"思政元素"有机融入医学免疫学课程教学中,实施"知识传授"与"... "课程思政"是加强高等学校大学生思想政治教育的重要途径,为更好地发挥"课程思政"的协同育人效应,基于医学免疫学的课程特点,把"思政元素"有机融入医学免疫学课程教学中,实施"知识传授"与"价值引领"同行并重,培养德才兼备的高素质医学人才。 展开更多
关键词 医学教育 课程思政 教学改革 医学免疫学
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High-frequency Grammatical Errors in Academic Writings by Chinese Students in International School
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作者 梁硕方 于红娟 裴倩琦 《海外英语》 2021年第5期265-269,共5页
This research investigates four categories of high-frequency grammatical errors from 45 students’academic writings via script analysis.A group of 36 students responded to a questionnaire focusing on their beliefs reg... This research investigates four categories of high-frequency grammatical errors from 45 students’academic writings via script analysis.A group of 36 students responded to a questionnaire focusing on their beliefs regarding these grammatical constructions.The participants are enrolled in an international school in Suzhou City.A total of 646 sentences were analyzed,among which295(45.7%)are inaccurate.Of the 364 errors found,most of them(64.0%)fall into the category of Subject-verb agreement,followed by subordinate clauses(28.6%);errors in English existential construction and the passive voice are a few.Also,the usage rate of subordinate clause is 42.7%,of which a large proportion was incorrect. 展开更多
关键词 error analysis students’beliefs academic writing Subject-verb agreement English existential construction passive voice subordinate clause
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调经活血胶囊治疗原发性痛经的多中心临床研究 被引量:14
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作者 于红娟 朱虹丽 +1 位作者 蒋贵林 王赛莉 《中草药》 CAS CSCD 北大核心 2018年第11期2624-2628,共5页
目的评价调经活血胶囊治疗原发性痛经的有效性。方法纳入300例原发性痛经妇女,按1∶2的比例随机分为对照组和治疗组,分别服用安慰剂和调经活血胶囊。连续服用3个月经周期后,使用视觉模拟评分(VAS评分)和中医证候积分评价调经活血胶囊对... 目的评价调经活血胶囊治疗原发性痛经的有效性。方法纳入300例原发性痛经妇女,按1∶2的比例随机分为对照组和治疗组,分别服用安慰剂和调经活血胶囊。连续服用3个月经周期后,使用视觉模拟评分(VAS评分)和中医证候积分评价调经活血胶囊对改善原发性痛经的临床疗效。结果治疗组患者连用3个月经周期后,VAS评分改善有效率达到62.43%,与对照组(23.33%)相比,差异显著(P<0.01)。中医临床疗效结果显示,调经活血胶囊治疗3个月经周期后,临床疗效总进步率达76.30%,显著优于对照组(36.67%)。结论调经活血胶囊可有效缓解原发性痛经患者的痛经程度。 展开更多
关键词 调经活血胶囊 原发性痛经 VAS评分 中医临床证候积分 多中心临床研究
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Anti-parasitic effects of water-soluble alkaloid fractions from ethanolic extracts of Sophora moorcroftiana seeds in Caenorhabditis elegans 被引量:3
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作者 LUO Yan-Ping ZHANG yuan +8 位作者 ZHANG Hui-Min ZHANG Hong ZHANG Lin yu hong-juan CAO Ming-Qiang SHI Yan-Bin ZHI De-Juan MA Xing-Ming DONG Kai-Zhong 《Chinese Journal of Natural Medicines》 SCIE CAS CSCD 2018年第9期665-673,共9页
Parasite infections of humans and animals remain a major global health problem, with limited choice of drugs being available to the treatment of parasitosis in the clinic. Sophora moorcroftiana(S. moorcroftiana) is a ... Parasite infections of humans and animals remain a major global health problem, with limited choice of drugs being available to the treatment of parasitosis in the clinic. Sophora moorcroftiana(S. moorcroftiana) is a shrub that grows in Tibet Plateau of China. Decoction of the seeds has been used as a traditional Tibetan medicine to treat parasitosis for years. But the anti-parasitic effects of water-soluble fractions in the seeds need further investigation. In the present study, the water-soluble alkaloid fractions(E2) were obtained from S. moorcroftiana seeds by refluxing extraction with 60% ethanol and low polarity fraction(E2-a) and high polarity fraction(E2-b) were subsequently isolated from E2 using column chromatography. As a parasite model, Caenorhabditis elegans(C. elegans) were treated with different fractions and their survivals were recorded. The results showed that that E2-a induced a lower survival rate in C. elegans than E2-b and E2. The protoscoleces of Echinococcus granulosus(E. granulosus) were cultured in the presence of E2-a. Compared with E2-b and E2, protoscoleces exhibited decreased survival rate following E2-a treatment. Furtherly, the effects of E2-a on the behavior, brood size, and lifespan of the worms were investigated. Body bend frequencies of the worms treated with the high concentration of E2-a were reduced by two-thirds compared with the control group(P < 0.01). Compared with non-E2-a-treated group, exposure of nematodes to E2-a led to a decrease in head thrashes and pharyngeal pumps frequency(P < 0.01). E2-a treatment resulted in a significantly lower brood size(P < 0.01). Additional E2-a treatment induced a significantly shortened lifespan, compared with the control(P < 0.05). These findings indicated that water-soluble fraction E2-a from S. moorcroftiana seeds was a potential helminthic agent. 展开更多
关键词 SOPHORA moorcroftiana ALKALOIDS ANTHELMINTICS CAENORHABDITIS elegans Protoscoleces
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