目的 探讨非对称回波最小二乘估算法迭代水脂分离序列(iterative decomposition of water and fat with echo asymmetrical and least-squares estimation quantitation sequence, IDEAL-IQ)来源的R2^(*)值在乳腺良恶性肿瘤鉴别诊断中...目的 探讨非对称回波最小二乘估算法迭代水脂分离序列(iterative decomposition of water and fat with echo asymmetrical and least-squares estimation quantitation sequence, IDEAL-IQ)来源的R2^(*)值在乳腺良恶性肿瘤鉴别诊断中的价值,并与传统多回波T2^(*)梯度回波(gradient recalled echo, GRE)序列来源的R2^(*)值进行比较。材料与方法 回顾性分析2021年9月至2023年10月在中国医科大学附属第一医院连续收治的42名患者的50个良性肿瘤病灶,在本院影像归档和通信系统(picture archiving and communication systems, PACS)中使用倾向性评分匹配方法匹配肿瘤所在最大层面的最长径,按1∶3的比例纳入150名患者的150个恶性肿瘤病灶。将恶性肿瘤根据预后因子[雌激素受体(estrogen receptor, ER)、孕激素受体(progesterone receptor, PR)以及人表皮生长因子受体2(human epidermal growth factor receptor 2, HER-2)]的阳性/阴性表达情况进行分组。所有患者均接受包含IDEAL-IQ和多回波T2*GRE序列的多参数MRI,测量以下定量参数:IDEAL-IQ序列R2^(*)值(R2^(*)IDEAL)、多回波T2*GRE序列R2^(*)值(R2^(*)GRE)、表观扩散系数(apparent diffusion coefficient, ADC)及肿瘤长径。根据原始资料类型的不同,分别利用单因素分析(独立样本t检验、Mann-Whitney U检验等方法)对比分析各参数的差异。采用Spearman相关性分析R2^(*)IDEAL与R2^(*)GRE及二者与ADC的相关性。采用配对样本t检验比较R2^(*)IDEAL与R2^(*)GRE的差异。采用logistic回归分析建立联合诊断模型,并使用受试者工作特征(receiver operating characteristic, ROC)曲线及曲线下面积(area under the curve,AUC)分析单独及联合参数鉴别乳腺肿瘤良恶性的效能。结果 相关性分析显示乳腺肿瘤患者的R2^(*)IDEAL与R2^(*)GRE呈中度相关(r=0.763,P<0.001),二者与ADC值均呈负性弱相关[r=-0.300(R2^(*)IDEAL),-0.306(R2^(*)GRE),P<0.001]。良性组与恶性组中,R2^(*)IDEAL与R2^(*)GRE均呈中度相关(r=0.745、0.680,P<0.001),二者与ADC均无相关性。两种序列所得的R2^(*)值差异有统计学意义(P<0.001)。R2^(*)IDEAL在良恶性组间差异有统计学意义(P<0.001),管腔HER-2阴性型R2^(*)值最高。对于单一参数,ADC值鉴别良恶性的AUC最高(0.857);对于联合参数,R2^(*)IDEAL+ADC鉴别良性组与管腔阴性组的AUC最高(0.927);差异均有统计学意义(P<0.05)。结论 IDEAL-IQ序列生成的R2^(*)值可用于区分良恶性乳腺肿块,可能成为除ADC外辅助乳腺肿瘤良恶性鉴别的又一无需对比剂参数。展开更多
The effective use of land in Northeast China is of great significance for ensuring national food security and regional rural revitalization.In this study,based on the survey data collected from Jilin Province,Northeas...The effective use of land in Northeast China is of great significance for ensuring national food security and regional rural revitalization.In this study,based on the survey data collected from Jilin Province,Northeast China,we analyzed the vacancy rates of rural homesteads in suburban,outer suburban,and remote villages,as well as the withdrawal intention of rural-settled farmers,urbansettled farmers,and farmers with urban and rural dual residency from vacant homesteads.From the perspective of farmers’perceptions,this study constructed a theoretical framework of the influence mechanism of their withdrawal intention and analyzed such mechanism by constructing a structural equation model.The results indicated that:1)rural homestead vacancy rates increased with distance from the village to the city.2)rural-settled farmers showed a low withdrawal intention for vacant rural homesteads,followed by urban and rural dual-residence farmers,and urban-settled farmers showed the highest withdrawal intention.3)the relative importance of the factors influencing withdrawal intention is in the following order:policy awareness>interest perception>living environment perception>family characteristics.Finally,this study discussed the reformation of the homestead system and rural homestead transition in Northeast China,which can provide policy support to increase the potential of cultivated land and promote sustainable rural development and urban-rural coordination.展开更多
基金Under the auspices of Strategic Priority Research Program of the Chinese Academy of Sciences (No. XDA28100405,XDA28020403)National Natural Science Foundation of China (No. 41771179, 42071275)+1 种基金Talents Training Project Supported by the Central Government for the Reform and Development of Local UniversitiesYoung Scientist Group Project of Northeast Institute of Geography and Agroecology,Chinese Academy of Sciences (No. 2022QNXZ02)
文摘The effective use of land in Northeast China is of great significance for ensuring national food security and regional rural revitalization.In this study,based on the survey data collected from Jilin Province,Northeast China,we analyzed the vacancy rates of rural homesteads in suburban,outer suburban,and remote villages,as well as the withdrawal intention of rural-settled farmers,urbansettled farmers,and farmers with urban and rural dual residency from vacant homesteads.From the perspective of farmers’perceptions,this study constructed a theoretical framework of the influence mechanism of their withdrawal intention and analyzed such mechanism by constructing a structural equation model.The results indicated that:1)rural homestead vacancy rates increased with distance from the village to the city.2)rural-settled farmers showed a low withdrawal intention for vacant rural homesteads,followed by urban and rural dual-residence farmers,and urban-settled farmers showed the highest withdrawal intention.3)the relative importance of the factors influencing withdrawal intention is in the following order:policy awareness>interest perception>living environment perception>family characteristics.Finally,this study discussed the reformation of the homestead system and rural homestead transition in Northeast China,which can provide policy support to increase the potential of cultivated land and promote sustainable rural development and urban-rural coordination.
