A new and convenient procedure was developed for the preparation of sulfonamides and sulfonic esters using N-fluorobenzenesulfonimide（NFSI） as a novel phenylsulfonyl group transfer reagent. In this protocol, a broad...A new and convenient procedure was developed for the preparation of sulfonamides and sulfonic esters using N-fluorobenzenesulfonimide（NFSI） as a novel phenylsulfonyl group transfer reagent. In this protocol, a broad range of functional groups were tolerated to give the corresponding sulfonamides or sulfonic esters in moderate to excellent yields. The synthetic strategy for sulfonamides formation proceeded efficiently even under base-, metal- and additive-free conditions with the advantages of operational simplicity, mild reaction conditions as well as short reaction time.展开更多
t-BuOK-promoted synthesis of bis（indolyl）arylmethunes from aromatic aldehydes and indoles wasachieved. Substrates bearing different functional groups, especially groups which are sensitive to acidic media, arewell t...t-BuOK-promoted synthesis of bis（indolyl）arylmethunes from aromatic aldehydes and indoles wasachieved. Substrates bearing different functional groups, especially groups which are sensitive to acidic media, arewell tolerated under the optimal condition, making this reaction particularly attractive for expanding the scope of thepresent protocols that provides bis（1H-indol-3-yl）arylmethanes.展开更多
基金Supported by the National Natural Science Foundation of China（Nos. 81373259, 81573286）.
文摘A new and convenient procedure was developed for the preparation of sulfonamides and sulfonic esters using N-fluorobenzenesulfonimide（NFSI） as a novel phenylsulfonyl group transfer reagent. In this protocol, a broad range of functional groups were tolerated to give the corresponding sulfonamides or sulfonic esters in moderate to excellent yields. The synthetic strategy for sulfonamides formation proceeded efficiently even under base-, metal- and additive-free conditions with the advantages of operational simplicity, mild reaction conditions as well as short reaction time.
文摘t-BuOK-promoted synthesis of bis（indolyl）arylmethunes from aromatic aldehydes and indoles wasachieved. Substrates bearing different functional groups, especially groups which are sensitive to acidic media, arewell tolerated under the optimal condition, making this reaction particularly attractive for expanding the scope of thepresent protocols that provides bis（1H-indol-3-yl）arylmethanes.
