目的探讨肾混合性上皮间质肿瘤(mixed epithelial and stromal tumor of the kidney,MESTK)的影像学及病理学特点。方法报告3例MESTK的女性患者,多层螺旋CT平扫及增强扫描可见不规则囊性病变,边界清楚,局部凸向肾盂,病灶多囊状,囊壁实...目的探讨肾混合性上皮间质肿瘤(mixed epithelial and stromal tumor of the kidney,MESTK)的影像学及病理学特点。方法报告3例MESTK的女性患者,多层螺旋CT平扫及增强扫描可见不规则囊性病变,边界清楚,局部凸向肾盂,病灶多囊状,囊壁实性密度,囊内密度较均匀,增强扫描囊内无强化,囊壁呈中等程度强化,延迟扫描持续强化,术后病理为右肾混合性上皮间质肿瘤。结果肾混合性上皮间质肿瘤具有较特异的影像学表现,结合本病例及以往文献报道病例,MESTK的CT扫描肿瘤呈多房囊实性,部分可凸向肾盂内。所有病例术后随访1年,未见复发及转移。结论肾脏混合性上皮间质瘤临床上罕见,以女性多见,无特征性临床表现,生物学行为大部分为良性,多层螺旋CT平扫及增强扫描具有一定诊断价值。展开更多
目的建立不同主产区金银花质量分析的综合评价模型。方法选取抗病毒活性主要成分绿原酸、木犀草苷、咖啡酰奎宁酸,影响质量安全的铅、镉、砷、汞、铜5个重金属指标以及二氧化硫残留和农药残留检出种类数量为评价指标,使用熵权法结合变...目的建立不同主产区金银花质量分析的综合评价模型。方法选取抗病毒活性主要成分绿原酸、木犀草苷、咖啡酰奎宁酸,影响质量安全的铅、镉、砷、汞、铜5个重金属指标以及二氧化硫残留和农药残留检出种类数量为评价指标,使用熵权法结合变异系数法计算组合权重,运用加权逼近理想解排序法(technique for order preference by similarity to ideal solution,TOPSIS)、加权秩和比法(rank sum ratio,RSR)及两者模糊联合的方法构建评价模型。结果引用《金银花采收加工及质量评价方法研究》中的数据为例,结果表明构建的模型运用在金银花质量评价中是可靠的。结论运用熵权-变异系数组合权重评价方法构建模型可以避免单一评价方法的缺点,更加真实地反映不同产区金银花的品质。展开更多
Fe-3Si steel strip was produced by thin slab casting and rolling (TSCR) process in the laboratory. The microstructure and texture of hot rolled strip by different total reduction and rolling schedules were observed ...Fe-3Si steel strip was produced by thin slab casting and rolling (TSCR) process in the laboratory. The microstructure and texture of hot rolled strip by different total reduction and rolling schedules were observed through EBSD technique and X-ray diffraction method. The rule of texture density for the a,ε and γ fibers was analyzed. When the total reduction was increased from 82.9% to 97.1%, the gradient of microstrueture and texture for A steel surface layer and center layer was found, {001}〈110〉 texture had higher intensity, and {001}〈110〉texture was changed to { 110 } 〈 001 〉 and { 112 } 〈 111 〉. The texture distribution with different reduction schedules for B steel was basically similar, but the Goss texture orientation density and volume fraction for B steel were higher, the hot rolling reduction schedule of C1 was effective for the formation of Goss texture. The research work was useful theoretical basis and reference data to develop electrical steel by thin slab continuous casting and direct rolling technology.展开更多
文摘目的探讨肾混合性上皮间质肿瘤(mixed epithelial and stromal tumor of the kidney,MESTK)的影像学及病理学特点。方法报告3例MESTK的女性患者,多层螺旋CT平扫及增强扫描可见不规则囊性病变,边界清楚,局部凸向肾盂,病灶多囊状,囊壁实性密度,囊内密度较均匀,增强扫描囊内无强化,囊壁呈中等程度强化,延迟扫描持续强化,术后病理为右肾混合性上皮间质肿瘤。结果肾混合性上皮间质肿瘤具有较特异的影像学表现,结合本病例及以往文献报道病例,MESTK的CT扫描肿瘤呈多房囊实性,部分可凸向肾盂内。所有病例术后随访1年,未见复发及转移。结论肾脏混合性上皮间质瘤临床上罕见,以女性多见,无特征性临床表现,生物学行为大部分为良性,多层螺旋CT平扫及增强扫描具有一定诊断价值。
文摘目的评价皮下免疫治疗(subcutaneous immunotherapy,SCIT)在过敏性鼻炎和过敏性哮喘中的疗效及安全性。方法采用多中心、横断面调查研究方法对2020年1月至2020年12月11家医疗机构的患者进行问卷调查,比较SCIT治疗前后过敏性鼻炎患者鼻结膜炎症状及用药评分,哮喘患者用药情况、哮喘控制测试(asthma control test,ACT)评分和哮喘急性加重次数。总结分析SCIT过程中的局部及全身不良反应。结果246例过敏性鼻炎和/或过敏性哮喘患者纳入研究,96.7%患者经SCIT治疗后自觉临床症状改善,SCIT治疗的中位起效时间为1(1,2)年。SCIT治疗前后,鼻结膜炎症状[1.8(1.3,2.5)vs.1(0.5,1.3)]、鼻结膜炎用药评分[2(1,2)vs.1(0,2)]、ACT评分[(16.0±4.6)vs.(21.4±3.3)]差异有统计学意义(P<0.001)。SCIT治疗后,口服抗组胺药、抗组胺喷鼻剂、抗组胺药滴眼液、激素类喷鼻剂、激素类滴眼液、口服白三烯受体拮抗剂和口服茶碱类药物的用药时间缩短(P<0.05)。哮喘患者在SCIT后停用吸入激素的比例较治疗前增加[52例(34.2%)vs.72例(47.4%)],因急性加重急诊就诊次数减少(P<0.001)。共89例患者出现注射局部不良反应;24例患者出现27例次全身不良反应,占全部总注射次数的0.035%(27次/77000次);22例次在注射30 min内发生,92.5%(25/27)与注射花粉变应原相关。结论应用皮下注射免疫治疗可安全、有效的治疗过敏性鼻炎和过敏性哮喘。
文摘目的建立不同主产区金银花质量分析的综合评价模型。方法选取抗病毒活性主要成分绿原酸、木犀草苷、咖啡酰奎宁酸,影响质量安全的铅、镉、砷、汞、铜5个重金属指标以及二氧化硫残留和农药残留检出种类数量为评价指标,使用熵权法结合变异系数法计算组合权重,运用加权逼近理想解排序法(technique for order preference by similarity to ideal solution,TOPSIS)、加权秩和比法(rank sum ratio,RSR)及两者模糊联合的方法构建评价模型。结果引用《金银花采收加工及质量评价方法研究》中的数据为例,结果表明构建的模型运用在金银花质量评价中是可靠的。结论运用熵权-变异系数组合权重评价方法构建模型可以避免单一评价方法的缺点,更加真实地反映不同产区金银花的品质。
基金Item Sponsored by National Natural Science Foundation of China(50534020)
文摘Fe-3Si steel strip was produced by thin slab casting and rolling (TSCR) process in the laboratory. The microstructure and texture of hot rolled strip by different total reduction and rolling schedules were observed through EBSD technique and X-ray diffraction method. The rule of texture density for the a,ε and γ fibers was analyzed. When the total reduction was increased from 82.9% to 97.1%, the gradient of microstrueture and texture for A steel surface layer and center layer was found, {001}〈110〉 texture had higher intensity, and {001}〈110〉texture was changed to { 110 } 〈 001 〉 and { 112 } 〈 111 〉. The texture distribution with different reduction schedules for B steel was basically similar, but the Goss texture orientation density and volume fraction for B steel were higher, the hot rolling reduction schedule of C1 was effective for the formation of Goss texture. The research work was useful theoretical basis and reference data to develop electrical steel by thin slab continuous casting and direct rolling technology.