The incidence of cathartic colon has been increasing,but satisfactory treatments are still lacking.In order to study the pathological mechanisms of the disorder and identify effective treatment methods,researchers hav...The incidence of cathartic colon has been increasing,but satisfactory treatments are still lacking.In order to study the pathological mechanisms of the disorder and identify effective treatment methods,researchers have established different animal models of cathartic colon.This minireview briefly summarizes several common cathartic colon animal models,induced with anthraquinone laxatives such as rhubarb,total anthraquinone,rhein,and emodin,or induced with diphenylmethane laxatives such as phenolphthalein.The advantages and limitations of these models are evaluated and analyzed.We hope that this review will facilitate the selection of suitable models and improve relevant modeling methods.We anticipate the development of more convenient and stable models that can reflect the characteristics of cathartic colon in humans,and serve as useful tools for further studies.展开更多
便秘型肠易激综合征(irritable bowel syndrome with constipation,IBS-C)病因病机仍未被完全阐明,缺乏令人满意的治疗手段,临床发病率不断上升,常常给患者的生活造成不同程度的影响.本文总结了近年来中医(traditional Chinese medicine...便秘型肠易激综合征(irritable bowel syndrome with constipation,IBS-C)病因病机仍未被完全阐明,缺乏令人满意的治疗手段,临床发病率不断上升,常常给患者的生活造成不同程度的影响.本文总结了近年来中医(traditional Chinese medicine,TCM)对IBS-C的病因病机的认识和常用的有效的治疗方法,为进一步研究TCM对IBS-C的作用提供一定的参考.展开更多
The screw air-source heat pump can cause incessant high noise levels during operation,which might hinder adoption of this energy-efficient heat pump.First,acoustic measurements and comparison testing were performed in...The screw air-source heat pump can cause incessant high noise levels during operation,which might hinder adoption of this energy-efficient heat pump.First,acoustic measurements and comparison testing were performed in this research.The measurements revealed that the compressor is the main noise source of the heat pump,and it shows a multipeak frequency distribution and a wide frequency spectrum under different work conditions,with multiple peaks at 63,250,and 1000 Hz.Then,a compressor sound insulation cover with broadband absorption was proposed,and it was experimentally proven that the insulation cover can reduce the maximum sound pressure level of one unit from 89.8 dBA to 79.1 dBA.Third,we proposed several noise reduction strategies and compared their noise reduction effects using computer simulation.The results showed that the noise problem can be effectively improved through the rational design of the sound barrier and the layout and opening options of heat pump.The distance between the sound barrier and heat pump and the sound attenuation due to diffraction ALa exhibit a U-shaped relation.For buildings of different heights,the optimal heights of noise barrier are proposed.The 5.5-meter is the optimal height of the sound barrier for single-story buildings.The conclusions can be applied to other building projects for heat pump noise reduction.展开更多
基金Supported by Xinglin Scholar,Xinglin Young Talent Program,No.RC-2017-02-07Shanghai Three-year Action Plan for Accelerating the Development of Traditional Chinese Medicine,No.ZY(2018-2020)-CCCX-2002-01and Research Fund of Longhua Hospital,No.2018YM05.
文摘The incidence of cathartic colon has been increasing,but satisfactory treatments are still lacking.In order to study the pathological mechanisms of the disorder and identify effective treatment methods,researchers have established different animal models of cathartic colon.This minireview briefly summarizes several common cathartic colon animal models,induced with anthraquinone laxatives such as rhubarb,total anthraquinone,rhein,and emodin,or induced with diphenylmethane laxatives such as phenolphthalein.The advantages and limitations of these models are evaluated and analyzed.We hope that this review will facilitate the selection of suitable models and improve relevant modeling methods.We anticipate the development of more convenient and stable models that can reflect the characteristics of cathartic colon in humans,and serve as useful tools for further studies.
文摘便秘型肠易激综合征(irritable bowel syndrome with constipation,IBS-C)病因病机仍未被完全阐明,缺乏令人满意的治疗手段,临床发病率不断上升,常常给患者的生活造成不同程度的影响.本文总结了近年来中医(traditional Chinese medicine,TCM)对IBS-C的病因病机的认识和常用的有效的治疗方法,为进一步研究TCM对IBS-C的作用提供一定的参考.
基金supported by the National Key R&D Program of China(No.2021YFB1507203)the National Natural Science Foundation of China(No.51838007).
文摘The screw air-source heat pump can cause incessant high noise levels during operation,which might hinder adoption of this energy-efficient heat pump.First,acoustic measurements and comparison testing were performed in this research.The measurements revealed that the compressor is the main noise source of the heat pump,and it shows a multipeak frequency distribution and a wide frequency spectrum under different work conditions,with multiple peaks at 63,250,and 1000 Hz.Then,a compressor sound insulation cover with broadband absorption was proposed,and it was experimentally proven that the insulation cover can reduce the maximum sound pressure level of one unit from 89.8 dBA to 79.1 dBA.Third,we proposed several noise reduction strategies and compared their noise reduction effects using computer simulation.The results showed that the noise problem can be effectively improved through the rational design of the sound barrier and the layout and opening options of heat pump.The distance between the sound barrier and heat pump and the sound attenuation due to diffraction ALa exhibit a U-shaped relation.For buildings of different heights,the optimal heights of noise barrier are proposed.The 5.5-meter is the optimal height of the sound barrier for single-story buildings.The conclusions can be applied to other building projects for heat pump noise reduction.
