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炎症--加速癌症转移的驱动力 被引量:26
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作者 yadi wu Binhua P.ZHOU +2 位作者 丁燕(翻译) 南娟(翻译) 刘谦(校对) 《中国肺癌杂志》 CAS 2009年第11期1194-1201,共8页
肿瘤微环境在癌变中发挥重要作用,这一点已经得到越来越多的共识。炎症组分存在并有助于肿瘤增殖、血管生成、转移以及对激素和化疗的抵抗。本文聚焦炎症在肿瘤转移中的作用。我们关注促炎因子特别是细胞因子在肿瘤转移中的作用。了解... 肿瘤微环境在癌变中发挥重要作用,这一点已经得到越来越多的共识。炎症组分存在并有助于肿瘤增殖、血管生成、转移以及对激素和化疗的抵抗。本文聚焦炎症在肿瘤转移中的作用。我们关注促炎因子特别是细胞因子在肿瘤转移中的作用。了解炎症促进肿瘤转移的机制将为癌症治疗带来创新性的突破。 展开更多
关键词 炎症 上皮-间质转化 转移
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Aldh2 deficiency plays a dual role in lung tumorigenesis and tumor progression
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作者 Hongjia Zhang Xueqian Sun +19 位作者 Zhanming Li Tingting Liu Fang Zhang Xinyu Meng Kaimi Li Jianhua Xu Wei He Bo Jing Tong Wang Na Ni Beibei Sun Feng Yao yadi wu Qi Wang Jing Du Eugene Y.Chin Binhua P.Zhou Ping Jiang Lishun Wang Jiong Deng 《Genes & Diseases》 SCIE CSCD 2024年第3期144-147,共4页
Alcohol consumption contributes to global mortality and cancer development.Acetaldehyde(ACE),the oxidized metabolite of alcohol,is highly reactive towards DNA,resulting in DNA adducts.ACE can be detoxified to acetate ... Alcohol consumption contributes to global mortality and cancer development.Acetaldehyde(ACE),the oxidized metabolite of alcohol,is highly reactive towards DNA,resulting in DNA adducts.ACE can be detoxified to acetate by acetaldehyde dehydrogenase type 2(ALDH2).ALDH2 deficiency can lead to ACE accumulation and DNA damage. 展开更多
关键词 MORTALITY DAMAGE ALDH2
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Modules of the Intermediate Series over Not-finitely Graded Lie Algebras W(Г)
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作者 yadi wu Xiaoqing Yue 《Algebra Colloquium》 SCIE CSCD 2021年第2期319-336,共18页
Let W(Г)be a class of not-finitely graded Lie algebras related to generalized Virasoro algebras with basis{L_(α,i),C|α∈Г,i∈Z_(+)},which satisfies relations[L_(α,i),L_(β,j)]=L_(α+β,i+j)+(j-i)L_(α+β,i+j+1)+... Let W(Г)be a class of not-finitely graded Lie algebras related to generalized Virasoro algebras with basis{L_(α,i),C|α∈Г,i∈Z_(+)},which satisfies relations[L_(α,i),L_(β,j)]=L_(α+β,i+j)+(j-i)L_(α+β,i+j+1)+δ_(α+β,0)δ_(i+j),0α^(3)-α/12 C and[C,L_(α,i)]=0.In this paper,W(Г)-modules of the intermediate series satisfying some conditions are constructed and classified.We also obtain modules of the intermediate series over the related Lie superalgebra. 展开更多
关键词 modules of intermediate series generalized Virasoro algebras not-finitely graded Lie algebras Lie superalgebras
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