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Pharmacokinetic interaction between irbesartan and Orthosiphon stamineus extract in rat plasma 被引量:1
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作者 Nur Meilis yahdiana harahap +2 位作者 Fadlina Chany Saputri Abdul Munim Rianto Setiabudy 《Asian Journal of Pharmaceutical Sciences》 SCIE CAS 2016年第1期70-71,共2页
Orthosiphonstamineus commonly known as kumis kucing has been used traditionally for rheumatoid,gout,renal calculus,hypertension,diabetes,etc.[1].It is often used in combination with synthetic hypertensive drugs like i... Orthosiphonstamineus commonly known as kumis kucing has been used traditionally for rheumatoid,gout,renal calculus,hypertension,diabetes,etc.[1].It is often used in combination with synthetic hypertensive drugs like irbesartan.However,both effectiveness combination herbal medicine with modern pharmaceuticals,and the possible adverse effects from herb–drug interactions remain to be verified. 展开更多
关键词 Orthosiphon stamineus IRBESARTAN PHARMACOKINETICS INTERACTION Herbs-drug INTERACTION
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Quantification of atorvastatin in human plasma by liquid chromatography tandem mass spectrometry and its application for bioequivalence study of three formulations
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作者 yahdiana harahap Santi Purnasari +5 位作者 Harmita Rina Rahmawati Krisnasari Dian Pratami Witri Sansris Siti Fatriyah 《Asian Journal of Pharmaceutical Sciences》 SCIE CAS 2016年第1期66-67,共2页
Atorvastatin, a chemical ([R-(R*, R*)]-2-(4-fluorophenyl)-b,ddihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]1 H-pyrole-1-heptanoic acid), is a synthetic HMG-Co A (3-hydroxy-3-methylglutaryl-coenzyme A)r... Atorvastatin, a chemical ([R-(R*, R*)]-2-(4-fluorophenyl)-b,ddihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]1 H-pyrole-1-heptanoic acid), is a synthetic HMG-Co A (3-hydroxy-3-methylglutaryl-coenzyme A)reductase inhibitor. It has been shown to be remarkably efficacious in decreasing the level of cholesterol and triglyceride(1)In order to quantify the level of atorvastatin in plasma, it needs a sensitive, rapid and selective method. 展开更多
关键词 ATORVASTATIN SIMVASTATIN LC-MS/MS
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