Objectives: There is a paucity of information on the prevalence of iron deficiency among blood donors in Sokoto, North Western, Nigeria. The present study was, therefore, designed to investigate the prevalence and soc...Objectives: There is a paucity of information on the prevalence of iron deficiency among blood donors in Sokoto, North Western, Nigeria. The present study was, therefore, designed to investigate the prevalence and socio-demographic factors associated with iron deficiency among blood donors in Sokoto, North Western, Nigeria using a combination of haemoglobin haematocrit and serum ferritin measurements. Materials and methods: One hundred and fifty consecutively recruited whole blood donors, comprising of 148 (98.7%) family replacement donors and 2 (1.3%) voluntary non-remunerated donors, 145 male (96.7%) and 5 (3.33%) female blood donors aged 18 - 60 years with mean age 39 ±?21 years constituted the subjects for this study. Subjects included farmers 55 (43.3%), 56 civil servants (37.3%) and 39 (26%) students. The full blood count was carried out using Mythic 22 CT fully automated haematology analyser (Orphee SA, Switzerland). Serum was tested for ferritin using a human ferritin enzyme immunoassay kit—ACCU DiagTM ELISA Ferritin kit (Diagnostic Automation/Cortez Diagnostic Inc. California (U.S.A). Result: Three haematological parameters (haemoglobin, packed cell volume and serum ferritin) were assessed among blood donors. The haemoglobin, packed cell volume and ferritin levels were significantly lower among regular voluntary remunerated blood donors (13.5 ±?0.00, 43.5 ±?2.0 and 34.88 ±?0.00) compared to Family replacement donors (14.10 ±?.40, 45 ±?3.0 and 74.12 ±?45.20) respectively (p =?0.01, 0.01 and 0.001 respectively). The mean haemoglobin, packed cell volume and ferritin levels were compared among donors based on gender. The haemoglobin, packed cell volume and ferritin were significantly higher among male donors (14.2 ±?2.0, 44 ±?4.0 and 78.02 ±?49.10) compared to female donors (12.35 ±?2.5, 42 ±?3.0 and 42.2 ±?32.13) (p =?0.01, 0.01 and 0.001 respectively). The mean haemoglobin, packed cell volume and ferritin levels were compared among donors based on occupational groups. The haemoglobin, packed cell volume and ferritin were significantly higher among civil servants compared to farmers and students (p =?0.01). Conclusion: Iron deficiency is prevalent among blood donors in Sokoto, North Western, Nigeria. There is a need to review the screening tests for the selection of blood donors and include serum ferritin measurement in the donor screening menu as well as provide iron supplementation for regular blood donors.展开更多
Objective:To investigate the prevalence and socio-demographic factors associated with iron deficiency anaemia among blood donors in Sokoto,North Western,Nigeria using a combination of haemoglobin haematocrit and serum...Objective:To investigate the prevalence and socio-demographic factors associated with iron deficiency anaemia among blood donors in Sokoto,North Western,Nigeria using a combination of haemoglobin haematocrit and serum ferritin measurements.Methods:One hundred and fifty consecutively recruited whole blood donors,comprising of 148(98.7%)family replacement donors and 2(1.3%)voluntary non-remunerated donors aged 18-60 years and mean age 39±21 years constituted the subjects for this study.The full blood count was carried out using Mythic 22 CT fully automated haematology analyser(Orphee SA,Switzerland).Serum was tested for ferritin using a human ferritin enzyme immunoassay kit-ACCU Diag^(™)ELISA Ferritin kit(Diagnostic Automation/Cortez Diagnostic Inc.California,USA).Results:The prevalence of anaemia(haemoglobin<11.0 g/dL)was evident in 24(16%)and iron deficiency anaemia(serum ferritin<12 ng/mL+haemoglobin<11 g/dL)in 5(10%)of donors.The haemoglobin and ferritin levels was significantly lower among regular voluntary remunerated blood donors(13.50±0.00 and 34.88±0.00)compared to family replacement donors(14.10±2.40 and 74.12±45.20)respectively(P=0.01 and 0.05 respectively).The mean haemoglobin and ferritin level was compared among donors based on gender.The haemoglobin and ferritin was significantly higher among male donors(14.20±2.00,78.02±49.10)compared to female donors(12.35±2.5 and 42.20±32.13)(P=0.01).The mean haemoglobin and ferritin level was compared among donors based on occupational groups.The haemoglobin and ferritin was significantly higher among civil servants compared to farmers and students(P=0.01).Conclusions:Iron deficiency anaemia is prevalent among blood donors in Sokoto,North Western,Nigeria.There is need to include routine ferritin in the blood donor testing protocol in the area to enable the diagnosis of donors with latent iron deficiency anaemia to facilitate iron supplementation for regular blood donors at risk and those with iron deficiency anaemia.展开更多
文摘Objectives: There is a paucity of information on the prevalence of iron deficiency among blood donors in Sokoto, North Western, Nigeria. The present study was, therefore, designed to investigate the prevalence and socio-demographic factors associated with iron deficiency among blood donors in Sokoto, North Western, Nigeria using a combination of haemoglobin haematocrit and serum ferritin measurements. Materials and methods: One hundred and fifty consecutively recruited whole blood donors, comprising of 148 (98.7%) family replacement donors and 2 (1.3%) voluntary non-remunerated donors, 145 male (96.7%) and 5 (3.33%) female blood donors aged 18 - 60 years with mean age 39 ±?21 years constituted the subjects for this study. Subjects included farmers 55 (43.3%), 56 civil servants (37.3%) and 39 (26%) students. The full blood count was carried out using Mythic 22 CT fully automated haematology analyser (Orphee SA, Switzerland). Serum was tested for ferritin using a human ferritin enzyme immunoassay kit—ACCU DiagTM ELISA Ferritin kit (Diagnostic Automation/Cortez Diagnostic Inc. California (U.S.A). Result: Three haematological parameters (haemoglobin, packed cell volume and serum ferritin) were assessed among blood donors. The haemoglobin, packed cell volume and ferritin levels were significantly lower among regular voluntary remunerated blood donors (13.5 ±?0.00, 43.5 ±?2.0 and 34.88 ±?0.00) compared to Family replacement donors (14.10 ±?.40, 45 ±?3.0 and 74.12 ±?45.20) respectively (p =?0.01, 0.01 and 0.001 respectively). The mean haemoglobin, packed cell volume and ferritin levels were compared among donors based on gender. The haemoglobin, packed cell volume and ferritin were significantly higher among male donors (14.2 ±?2.0, 44 ±?4.0 and 78.02 ±?49.10) compared to female donors (12.35 ±?2.5, 42 ±?3.0 and 42.2 ±?32.13) (p =?0.01, 0.01 and 0.001 respectively). The mean haemoglobin, packed cell volume and ferritin levels were compared among donors based on occupational groups. The haemoglobin, packed cell volume and ferritin were significantly higher among civil servants compared to farmers and students (p =?0.01). Conclusion: Iron deficiency is prevalent among blood donors in Sokoto, North Western, Nigeria. There is a need to review the screening tests for the selection of blood donors and include serum ferritin measurement in the donor screening menu as well as provide iron supplementation for regular blood donors.
文摘Objective:To investigate the prevalence and socio-demographic factors associated with iron deficiency anaemia among blood donors in Sokoto,North Western,Nigeria using a combination of haemoglobin haematocrit and serum ferritin measurements.Methods:One hundred and fifty consecutively recruited whole blood donors,comprising of 148(98.7%)family replacement donors and 2(1.3%)voluntary non-remunerated donors aged 18-60 years and mean age 39±21 years constituted the subjects for this study.The full blood count was carried out using Mythic 22 CT fully automated haematology analyser(Orphee SA,Switzerland).Serum was tested for ferritin using a human ferritin enzyme immunoassay kit-ACCU Diag^(™)ELISA Ferritin kit(Diagnostic Automation/Cortez Diagnostic Inc.California,USA).Results:The prevalence of anaemia(haemoglobin<11.0 g/dL)was evident in 24(16%)and iron deficiency anaemia(serum ferritin<12 ng/mL+haemoglobin<11 g/dL)in 5(10%)of donors.The haemoglobin and ferritin levels was significantly lower among regular voluntary remunerated blood donors(13.50±0.00 and 34.88±0.00)compared to family replacement donors(14.10±2.40 and 74.12±45.20)respectively(P=0.01 and 0.05 respectively).The mean haemoglobin and ferritin level was compared among donors based on gender.The haemoglobin and ferritin was significantly higher among male donors(14.20±2.00,78.02±49.10)compared to female donors(12.35±2.5 and 42.20±32.13)(P=0.01).The mean haemoglobin and ferritin level was compared among donors based on occupational groups.The haemoglobin and ferritin was significantly higher among civil servants compared to farmers and students(P=0.01).Conclusions:Iron deficiency anaemia is prevalent among blood donors in Sokoto,North Western,Nigeria.There is need to include routine ferritin in the blood donor testing protocol in the area to enable the diagnosis of donors with latent iron deficiency anaemia to facilitate iron supplementation for regular blood donors at risk and those with iron deficiency anaemia.
