Enhancement of microvessel in laser speckle image using gaussian kernel template

Laser speckle contrast imaging(LSCI)is an optical imaging method,which can monitor microvascularflow variation directly without addition of any ectogenous dye.All the existing laser speckle contrast analysis(LASCA)methods are a combination of spatial and temporal statistics.In this study,we have proposed a new method,Gaussian kernel laser speckle contrast analysis(gLASCA),which processes the raw images primarily with the Gaussian kernel operator along the spatial direction of bloodflow.We explored the properties of gLASCA in the simulation and animal cerebral ischemia perfusion model.Compared with the other existing speckle processing methods based on spatial,temporal,spatial-temporal or anisotropic linear structure;the present gLASCA method has a high spatial-temporal resolution to respond the change of velocity especially in microvasculature.Besides,the gLASCA method obtains approximately 10.2%and 7.1%higher contrast-to-noise ratio(CNR)over the anisotropic linear method(aLASCA)in the simulation and experiment models.For these advantages,gLASCA could be a better method for local microvascular laser speckle imaging in terms of cerebral ischemia reperfusion,spreading depression and brain injury diseases.

Interface properties and failures of REBCO coated conductor tapes:Research progress and challenges

RE‐Ba‐Cu‐O(REBCO,where RE=Y,Gd,Sm,and other rare earth elements)coated conductor(CC)tapes are promising for applications in high‐energy physics and high‐field science owing to their significant advantages such as high critical magnetic field,high current density,and the ability to achieve superconductivity at liquid nitrogen temperatures.Nevertheless,the mechanical and superconducting performances of these CC tapes are significantly affected by interface failures,such as interfacial delamination and coating fractures,which arise from the complex interplay of mechanical stress induced by magnet processing,thermal mismatch stress during cooling,electromagnetic stress under high magnetic fields,and thermal stress during quenching.This study comprehensively reviews the interface properties and failure behavior of REBCO CC tapes.First,the research progress in characterizing the intricate interface properties of REBCO CC is systematically reviewed.Furthermore,the interface failure behavior in extreme multifield environments was analyzed and summarized.Subsequently,this study outlines optimization strategies to mitigate interface failure risks in REBCO superconducting magnet structures.Finally,we address the current challenges and future perspectives on interface issues in REBCO CC tapes.By addressing these challenges,this study offers valuable insights for advancing the development and practical implementation of superconducting technologies in diverse applications.

"Dragon man"prompts rethinking of Middle Pleistocene hominin systematics in Asia

Dear Editor,Chibanian(Middle Pleistocene)hominin fossils that could not be easily assigned to Homo erectus,H.neanderthalensis,or H.sapiens have traditionally been as-signed to an alinclusive group:"archaic H.sapiens."In an insightful observation of the Chibanian record almost four decades ago however,Tattersall railed against the use of the word"archaic"in this sense when referring to the human fossil record,as he justifiably noted that no other biological organism has the word"archaic"attached to it'For example,no one refers to an earlier version of Canis domesticus as"archaic"C.domesticus.The ancestor of the domestic dog is,and always has been,considered to be C.lupus.In Tattersall's opinion,it would seem that these"archaic H.sapiens"fossils should be assigned to one or more formal taxonomic names.As such,terms such as"archaic H.sapiens,""mid-Pleistocene Homo,"and"Middle Pleistocene Homo"have al-ways been considered to be wastebasket taxa that include way too much morphological variabilty for one proposed taxonomic group.Continuing to use wastebasket taxa only hinders any attempts to understand true phylogenetic and evolutionary relationships.

技术妙手让“良品率”管理“如鱼得水”——以协鑫科技业财融合实践转型为例

长久以来,低良品率和高单位成本一直是制约光伏企业发展的关键因素,传统工业工程方法均收效甚微。数字化时代,业财融合这种依托于数字化技术推动价值信息协同共享,并通过价值信息输出支撑企业业务经营与管理提升的新管理模式应运而生,被奉为在不确定环境下企业谋求未来发展的破解之策。本文以协鑫科技业财融合转型实践为例,重点阐述业财融合如何激发良品率的提高和成本的降低,从而保持和提高企业的市场竞争力,以期对其他企业提供有益启示。

不同微生物大鼠腹腔注射模型尿液蛋白组学的比较

不同的微生物都可以引起腹腔感染,文中尝试利用尿液来区分不同的微生物感染。通过在大鼠腹腔内分别注射大肠杆菌、金黄色葡萄球菌和白色念球菌建立3种模型,收集感染后0、12、36、72 h的尿液,并使用液相色谱串联质谱技术(LC-MS/MS)对尿蛋白进行分析。与感染前相比,在大肠杆菌腹腔注射模型中共鉴定到69个差异蛋白,在金黄色葡萄球菌腹腔注射模型中共鉴定到31个差异蛋白,在白色念球菌腹腔注射模型中共鉴定到38个差异蛋白。结果表明,腹腔注射不同的微生物时尿蛋白质组不同,提示尿液可能对不同的腹腔感染有鉴别诊断的潜能。

Stability and Convergence of the Canonical Euler Splitting Method for Nonlinear Composite Stiff Functional Differential-Algebraic Equations

A novel canonical Euler splitting method is proposed for nonlinear compositestiff functional differential-algebraic equations, the stability and convergence of themethod is evidenced, theoretical results are further confirmed by some numerical experiments.Especially, the numerical method and its theories can be applied to specialcases, such as delay differential-algebraic equations and integral differential-algebraicequations.