Three 4β-(1,2,3-triazol-1-yl) podophyllotoxins 2~4 have been synthesized and testedtar their antitumor activity in vitro. The compound 3 was found to be much more cytotoxic than theclinically used etoposide (VP-16) ...Three 4β-(1,2,3-triazol-1-yl) podophyllotoxins 2~4 have been synthesized and testedtar their antitumor activity in vitro. The compound 3 was found to be much more cytotoxic than theclinically used etoposide (VP-16) against L 1210 cells.展开更多
文摘Three 4β-(1,2,3-triazol-1-yl) podophyllotoxins 2~4 have been synthesized and testedtar their antitumor activity in vitro. The compound 3 was found to be much more cytotoxic than theclinically used etoposide (VP-16) against L 1210 cells.