To the Editor: Dermatopathic lymphadenitis (DL) represents a rare benign lymphatic hyperplasia commonly associated with exfoliative or eczematoid dermatitis. DL was also reported to be a potential mimicker of lymph...To the Editor: Dermatopathic lymphadenitis (DL) represents a rare benign lymphatic hyperplasia commonly associated with exfoliative or eczematoid dermatitis. DL was also reported to be a potential mimicker of lymphoma. Here, we report the ^18F-fluorodeoxyglucose (^18F-FDG) positron emission tomography/ computer tomograpby (PET/CT) results and the histological findings of a 40-year-old female patient with DL.展开更多
Fluorodeoxyglucose positron emission tomography/conlputed tomography (FDG PET/CT) is widely applied in non-small cell lung cancer (NSCLC). The standardized uptake value (SUV), a semi-quantitative index, plays an...Fluorodeoxyglucose positron emission tomography/conlputed tomography (FDG PET/CT) is widely applied in non-small cell lung cancer (NSCLC). The standardized uptake value (SUV), a semi-quantitative index, plays an essential role in NSCLC tbr diagnosis, staging, and efficacy evaklation. It has been px3posed that the SUV of tumors may correlate with the presence or absence of chemotherapy resistance-associated biomarkers based on studies that have displayed a close correlation between SUV and the expression levels of excision repair cross-complementary Group 1 (ERCC 1 )1~1 and Tp53-induced glycolysis and apoptosis regulator.121 FDG avidity of NSCLC and ERCC 1 and ribonucleotide reductase subunit M 1 (RRM 1 ) levels have not been as extensively investigated. Based on these findings, we looked tbr correlations among metabolic parameters (SUVm,,. metabolic tumor volume [MTV], and total lesion glycolysis [TLG]) and ERCC1 and RRM1 expression in patients with NSCLC, to investigate whether FDG uptake reflects the presence or absence ofchemoresistance proteins (ERCC1 and RRM 1 ) within tumor cells.展开更多
文摘To the Editor: Dermatopathic lymphadenitis (DL) represents a rare benign lymphatic hyperplasia commonly associated with exfoliative or eczematoid dermatitis. DL was also reported to be a potential mimicker of lymphoma. Here, we report the ^18F-fluorodeoxyglucose (^18F-FDG) positron emission tomography/ computer tomograpby (PET/CT) results and the histological findings of a 40-year-old female patient with DL.
文摘Fluorodeoxyglucose positron emission tomography/conlputed tomography (FDG PET/CT) is widely applied in non-small cell lung cancer (NSCLC). The standardized uptake value (SUV), a semi-quantitative index, plays an essential role in NSCLC tbr diagnosis, staging, and efficacy evaklation. It has been px3posed that the SUV of tumors may correlate with the presence or absence of chemotherapy resistance-associated biomarkers based on studies that have displayed a close correlation between SUV and the expression levels of excision repair cross-complementary Group 1 (ERCC 1 )1~1 and Tp53-induced glycolysis and apoptosis regulator.121 FDG avidity of NSCLC and ERCC 1 and ribonucleotide reductase subunit M 1 (RRM 1 ) levels have not been as extensively investigated. Based on these findings, we looked tbr correlations among metabolic parameters (SUVm,,. metabolic tumor volume [MTV], and total lesion glycolysis [TLG]) and ERCC1 and RRM1 expression in patients with NSCLC, to investigate whether FDG uptake reflects the presence or absence ofchemoresistance proteins (ERCC1 and RRM 1 ) within tumor cells.