To the Editor:Gastric cancer(GC)is one of the most commonly diagnosed malignancies worldwide.[1,2]Recent studies show that an aberrant gastric microbiota contributes to the onset and progression of GC.[3]A distinct cl...To the Editor:Gastric cancer(GC)is one of the most commonly diagnosed malignancies worldwide.[1,2]Recent studies show that an aberrant gastric microbiota contributes to the onset and progression of GC.[3]A distinct cluster of bacteria consisting of Peptostreptococcus,Streptococcus,and Parvimonas among others is associated with gastric atrophy and intestinal metaplasia(IM).[4]However,the gastric microbiome is highly dynamic and influenced by several factors,including diet,xenobiotics,proton pump inhibitors,physiological changes,and host genetics.展开更多
文摘To the Editor:Gastric cancer(GC)is one of the most commonly diagnosed malignancies worldwide.[1,2]Recent studies show that an aberrant gastric microbiota contributes to the onset and progression of GC.[3]A distinct cluster of bacteria consisting of Peptostreptococcus,Streptococcus,and Parvimonas among others is associated with gastric atrophy and intestinal metaplasia(IM).[4]However,the gastric microbiome is highly dynamic and influenced by several factors,including diet,xenobiotics,proton pump inhibitors,physiological changes,and host genetics.