Oxygen deficient Nd_(0.67)Sr_(0.33)MnO_(3-δ) ceramic samples were prepared using conventional ceramic technology.A colossal electroresistance(CER)effect was found in Nd_(0.67)Sr_(0.33)MnO_(3-δ) series.The electrical...Oxygen deficient Nd_(0.67)Sr_(0.33)MnO_(3-δ) ceramic samples were prepared using conventional ceramic technology.A colossal electroresistance(CER)effect was found in Nd_(0.67)Sr_(0.33)MnO_(3-δ) series.The electrical transport is magnetically coupled and spin-dependent over grain or phase boundaries.Electrical-field-induced changes of the spin array orientations inside of and between the magnetic domains by grain or phase boundaries have to be concluded for the strong electroresistive effect in Nd_(0.67)Sr_(0.33)MnO_(3-δ) series.展开更多
Photothermal therapy is a direct and non-invasive therapeutic strategy.Herein,we report a general strategy for the construction of polyaniline-coated DNA nanoparticles for efficient photothermal therapy.In our design,...Photothermal therapy is a direct and non-invasive therapeutic strategy.Herein,we report a general strategy for the construction of polyaniline-coated DNA nanoparticles for efficient photothermal therapy.In our design,two G4/hemin-based DNAzymes are precisely organized in a DNA template to mimic the function of horseradish peroxidase(HRP)for the catalytic oxidation of aniline.After polymerization,the polyaniline-coated DNA nanoparticles(PANI/DNA NPs)can be efficiently obtained as the photothermal agent to elicit a pronounced photothermal effect.After cellular uptake,the noticeable photothermal effect from 808 nm laser irradiation can achieve an efficient proliferation inhibition of tumor cells.This rationally developed photothermal agent based on DNA template-assisted polymerization presents a new avenue for the development of photothermal therapy.展开更多
基金Project supported by the National Natural Science Foundation of China(10774040)Excellent Young Scientist Foundation of Hubei Province(2006ABB032)
文摘Oxygen deficient Nd_(0.67)Sr_(0.33)MnO_(3-δ) ceramic samples were prepared using conventional ceramic technology.A colossal electroresistance(CER)effect was found in Nd_(0.67)Sr_(0.33)MnO_(3-δ) series.The electrical transport is magnetically coupled and spin-dependent over grain or phase boundaries.Electrical-field-induced changes of the spin array orientations inside of and between the magnetic domains by grain or phase boundaries have to be concluded for the strong electroresistive effect in Nd_(0.67)Sr_(0.33)MnO_(3-δ) series.
基金supported by the National Key R&D Program of China(Nos.2021YFA1200302,2018YFA0208900)the National Natural Science Foundation of China(Nos.22025201,22077023,21721002)+2 种基金the Strategic Priority Research Program of Chinese Academy of Sciences(No.XDB36000000)the CAS Project for Young Scientists in Basic Research(No.YSBR-036)the CAS Interdisciplinary Innovation Team,Youth Innovation Promotion Association CAS,and K.C.Wong Education Foundation(No.GJTD-2018-03).
文摘Photothermal therapy is a direct and non-invasive therapeutic strategy.Herein,we report a general strategy for the construction of polyaniline-coated DNA nanoparticles for efficient photothermal therapy.In our design,two G4/hemin-based DNAzymes are precisely organized in a DNA template to mimic the function of horseradish peroxidase(HRP)for the catalytic oxidation of aniline.After polymerization,the polyaniline-coated DNA nanoparticles(PANI/DNA NPs)can be efficiently obtained as the photothermal agent to elicit a pronounced photothermal effect.After cellular uptake,the noticeable photothermal effect from 808 nm laser irradiation can achieve an efficient proliferation inhibition of tumor cells.This rationally developed photothermal agent based on DNA template-assisted polymerization presents a new avenue for the development of photothermal therapy.
