水声通信中传统宽带多普勒估计方法难以准确跟踪时变多普勒因子,从而导致正交频分复用(Orthogonal Frequency Division Multiplexing,OFDM)在变速运动通信场景中补偿性能不佳。针对该问题,文章提出了一种基于空载波的多普勒估计与跟踪...水声通信中传统宽带多普勒估计方法难以准确跟踪时变多普勒因子,从而导致正交频分复用(Orthogonal Frequency Division Multiplexing,OFDM)在变速运动通信场景中补偿性能不佳。针对该问题,文章提出了一种基于空载波的多普勒估计与跟踪算法。首先对三频信号做线性调频Z变换(Chirp-Z Transform,CZT)得到多普勒先验值,然后利用OFDM符号中的空载波结合载波频偏(Carrier Frequency Offset,CFO)搜索补偿技术,把估计的最优CFO值转换为宽带多普勒因子,进而计算当前符号的加速度并预测下一符号的速度。通过更新加速度对预测值进行修正,实现每个OFDM符号的多普勒估计。数值仿真和湖试结果表明,文中算法不仅能有效跟踪多普勒的变化,在匀速和变速条件下都有较好的补偿性能,而且对帧结构设计要求低,对先验误差不敏感,有利于水声通信系统的工程实现。展开更多
The one-pot synthesis of 6-hydroxyhexanoic acid from cyclohexanone via the integrated Baeyer-Villiger oxida-tion and ring opening reaction catalyzed by dealuminated HBEA zeolite has been developed. Under optimized con...The one-pot synthesis of 6-hydroxyhexanoic acid from cyclohexanone via the integrated Baeyer-Villiger oxida-tion and ring opening reaction catalyzed by dealuminated HBEA zeolite has been developed. Under optimized conditions,the cyclohexanone conversion and 6-hydroxyhexanoic acid selectivity are over 95%, respectively. The excellent catalyticperformance is attributed to the activation of carbonyl group of cyclohexanone and the fast hydrolysis and ring opening ofs-caprolactone by both Lewis acid and Br0nsted acid sites under aqueous conditions.展开更多
目的通过对两对患1型神经纤维瘤(neurofibromatosis type 1,NF1)的同卵双胞胎进行全基因组测序分析对比儿童先天性骨假关节(congenital pseudarthrosis,CP)表型和非CP表型患儿的分子特征,鉴定CP患儿的致病变异,并对相关表型和1型神经纤...目的通过对两对患1型神经纤维瘤(neurofibromatosis type 1,NF1)的同卵双胞胎进行全基因组测序分析对比儿童先天性骨假关节(congenital pseudarthrosis,CP)表型和非CP表型患儿的分子特征,鉴定CP患儿的致病变异,并对相关表型和1型神经纤维瘤致病基因NF1变异进行特征描述。方法根据胫骨假关节诊断标准和NF1临床诊断标准,纳入两对均患有NF1的同卵双胞胎,均为女性,且每对双胞胎中均仅1人有CP表型。对两对同卵双胞胎的外周血提取DNA进行全基因组测序,运用生物信息学方法分析单核苷酸变异(single nucleotide variant,SNV)、短插入缺失变异(short insertion deletion variants,InDel)、拷贝数变异(copy number variant,CNV)和结构变异(structural variant,SV),鉴定出涉及NF1基因的致病变异及CP患者特有的胚系致病变异;对鉴定出的致病变异在双胞胎及父母中进行一代测序验证。结果两对NF1型同卵双胞胎中均鉴定到NF1基因的致病胚系变异,分别为:c.3047_3048del(p.Cys1016SerfsTer4)和c.4267A>G(p.Lys1423Glu)杂合变异;经过家系4人的一代测序验证,表明均为新发变异。除NF1基因外,在CP患儿特有而未患CP的同胞姐妹没有的变异中,未鉴定到其他致病或可能致病的SNV/InDel、结构变异或CNV变异。进一步比较两对双胞胎中CP患儿特有的评级为意义不明的低频有害错义变异和功能缺失型SNV和InDels变异,发现这些变异共同影响的基因有1802个,无共同基因存在编码区的变异;评级为意义不明的结构变异或CNV变异所在的基因无交集,即无共同变异基因。结论全基因组测序分析揭示两对患有NF1同卵双胞胎均鉴定到了1型神经纤维瘤致病基因NF1的致病变异,未鉴定到双胞胎中CP患者特有的其他致病变异,且两个CP患者中未检测到其他的共同基因包含可能致病的变异。展开更多
文摘水声通信中传统宽带多普勒估计方法难以准确跟踪时变多普勒因子,从而导致正交频分复用(Orthogonal Frequency Division Multiplexing,OFDM)在变速运动通信场景中补偿性能不佳。针对该问题,文章提出了一种基于空载波的多普勒估计与跟踪算法。首先对三频信号做线性调频Z变换(Chirp-Z Transform,CZT)得到多普勒先验值,然后利用OFDM符号中的空载波结合载波频偏(Carrier Frequency Offset,CFO)搜索补偿技术,把估计的最优CFO值转换为宽带多普勒因子,进而计算当前符号的加速度并预测下一符号的速度。通过更新加速度对预测值进行修正,实现每个OFDM符号的多普勒估计。数值仿真和湖试结果表明,文中算法不仅能有效跟踪多普勒的变化,在匀速和变速条件下都有较好的补偿性能,而且对帧结构设计要求低,对先验误差不敏感,有利于水声通信系统的工程实现。
基金supported by the National Basic Research Program of China(973 Program,2006CB202508)the China Petrochemical Corporation Program(SINOPEC Group ST417004)the National Key Research and Development Program of China(2017YFB0306800)
文摘The one-pot synthesis of 6-hydroxyhexanoic acid from cyclohexanone via the integrated Baeyer-Villiger oxida-tion and ring opening reaction catalyzed by dealuminated HBEA zeolite has been developed. Under optimized conditions,the cyclohexanone conversion and 6-hydroxyhexanoic acid selectivity are over 95%, respectively. The excellent catalyticperformance is attributed to the activation of carbonyl group of cyclohexanone and the fast hydrolysis and ring opening ofs-caprolactone by both Lewis acid and Br0nsted acid sites under aqueous conditions.
