Boron-based metal-free catalysts for oxidative dehydrogenation of propane(ODHP)have drawn great attention in both academia and industry due to their impressive activity and olefin selectivity.Herein,the SiO2 and B2O3 ...Boron-based metal-free catalysts for oxidative dehydrogenation of propane(ODHP)have drawn great attention in both academia and industry due to their impressive activity and olefin selectivity.Herein,the SiO2 and B2O3 sequentially coated honeycomb cordierite catalyst is designed by a two-step wash-coat method with different B2O3 loadings(0.1%–10%)and calcination temperatures(600,700,800℃).SiO2 obtained by TEOS hydrolysis acts as a media layer to bridge the cordierite substrate and boron oxide via abundant Si\\OH groups.The welldeveloped straight channels of honeycomb cordierite make it possible to carry out the reactor under high gas hourly space velocity(GHSV)and the thin wash-coated B2O3 layer can effectively facilitate the pore diffusion on the catalyst.The prepared B2O3/SiO2@HC monolithic catalyst exhibits good catalytic performance at low boron oxide loading and achieves excellent propylene selectivity(86.0%),olefin selectivity(97.6%,propylene and ethylene)and negligible CO2(0.1%)at 16.9%propane conversion under high GHSV of 345,600 ml·(g B2O3)^-1·h^-1,leading to a high propylene space time yield of 15.7 g C3H6·(g B2O3)^-1·h^-1 by suppressing the overoxidation.The obtained results strongly indicate that the boron-based monolithic catalyst can be properly fabricated to warrant the high activity and high throughput with its high gas/surface ratio and straight channels.展开更多
Thinking of grey group model is the improvement on the traditional grey model. It does not merely use a grey model as the ultimate basis, but takes full account of the traditional GM （1,1） model and the GM （1, n） ...Thinking of grey group model is the improvement on the traditional grey model. It does not merely use a grey model as the ultimate basis, but takes full account of the traditional GM （1,1） model and the GM （1, n） model and join two predictions to form a prediction interval. So, the results are more reasonable and more realistic requirements and have strong guidance and reference. The farther the forecast period is, the worse the forecast is. The forecasts in the forecast period of 1-3 Years are the best, but the results of long-term are only as a reference value and the guidance data. Therefore, as the forecast period goes on, rolling grey model is used to increase accuracy.展开更多
To investigate the effects of lanthanum chloride on binding of LPS to monocyte and CD14 expression upregulation induced by LPS,human monocytes were analyzed by flow cytometry(FCM).The results indicated that lanthanum ...To investigate the effects of lanthanum chloride on binding of LPS to monocyte and CD14 expression upregulation induced by LPS,human monocytes were analyzed by flow cytometry(FCM).The results indicated that lanthanum chloride could decrease the binding rate of LPS with monocyte significantly.LPS upregulated the expression of CD14 on monocyte in a dose dependant manner,however,lanthanum chloride could inhibit the increase of CD14 expression on monocytes by halves.Cellular & Molecular Immunology. 2004;1(5):392-394.展开更多
Over the last decade the 3C-based （Chromosome Conformation Capture, 3C） approaches have been developed to describe the frequency of chromatin interaction. The invention of Hi-C allows us to obtain genome-wide chroma...Over the last decade the 3C-based （Chromosome Conformation Capture, 3C） approaches have been developed to describe the frequency of chromatin interaction. The invention of Hi-C allows us to obtain genome-wide chromatin interaction map. However, it is challenging to develop efficient and robust analytical tools to interpret the Hi-C data. Here we present a new method called Clustering based Hi-C Domain Finder （CHDF）, which is based on the difference of interaction intensity inside/outside domains, to identify Hi-C domains. We also compared CHDF with existing methods including Direction Index （DI） and HiCseg. CHDF can define more chromatin domains validated by higher resolution local chromatin structure data （Chromosome Conformation Capture Carbon Copy （5C） data）. Using Hi-C data of lower sequencing depth, chromatin structure identified by CHDF is closer to that discovered by data of higher sequencing depth. Furthermore, the implement of CHDF is faster than the other two. Using CHDF, we are potentially able to discover more hints and clues about chromatin structural elements at domain level.展开更多
Dr. Wiedermann commented on our systematic review and meta-regression tbr the sources of heterogeneity in trials reporting H ES 130/0.4 or 0.42 associated excess mortality in septic patients that the pooled analysis o...Dr. Wiedermann commented on our systematic review and meta-regression tbr the sources of heterogeneity in trials reporting H ES 130/0.4 or 0.42 associated excess mortality in septic patients that the pooled analysis of mortality, which showed neither benefit nor harm, might be influenced by trials of low-quality. Statistically, we agree with this conclusion if two of the recruited trials judged as the intermediate risk of bias are precluded.展开更多
基金supported by State Key Program of National Natural Science Foundation of China(21733002)Joint Sino-German Research Project(21761132011)Cheung Kong Scholars Programme of China(T2015036)。
文摘Boron-based metal-free catalysts for oxidative dehydrogenation of propane(ODHP)have drawn great attention in both academia and industry due to their impressive activity and olefin selectivity.Herein,the SiO2 and B2O3 sequentially coated honeycomb cordierite catalyst is designed by a two-step wash-coat method with different B2O3 loadings(0.1%–10%)and calcination temperatures(600,700,800℃).SiO2 obtained by TEOS hydrolysis acts as a media layer to bridge the cordierite substrate and boron oxide via abundant Si\\OH groups.The welldeveloped straight channels of honeycomb cordierite make it possible to carry out the reactor under high gas hourly space velocity(GHSV)and the thin wash-coated B2O3 layer can effectively facilitate the pore diffusion on the catalyst.The prepared B2O3/SiO2@HC monolithic catalyst exhibits good catalytic performance at low boron oxide loading and achieves excellent propylene selectivity(86.0%),olefin selectivity(97.6%,propylene and ethylene)and negligible CO2(0.1%)at 16.9%propane conversion under high GHSV of 345,600 ml·(g B2O3)^-1·h^-1,leading to a high propylene space time yield of 15.7 g C3H6·(g B2O3)^-1·h^-1 by suppressing the overoxidation.The obtained results strongly indicate that the boron-based monolithic catalyst can be properly fabricated to warrant the high activity and high throughput with its high gas/surface ratio and straight channels.
文摘Thinking of grey group model is the improvement on the traditional grey model. It does not merely use a grey model as the ultimate basis, but takes full account of the traditional GM （1,1） model and the GM （1, n） model and join two predictions to form a prediction interval. So, the results are more reasonable and more realistic requirements and have strong guidance and reference. The farther the forecast period is, the worse the forecast is. The forecasts in the forecast period of 1-3 Years are the best, but the results of long-term are only as a reference value and the guidance data. Therefore, as the forecast period goes on, rolling grey model is used to increase accuracy.
基金This work was supported by National Natural Science Foundation of China(30260107)the Natural Science Foundation of Jiangxi province(024008).
文摘To investigate the effects of lanthanum chloride on binding of LPS to monocyte and CD14 expression upregulation induced by LPS,human monocytes were analyzed by flow cytometry(FCM).The results indicated that lanthanum chloride could decrease the binding rate of LPS with monocyte significantly.LPS upregulated the expression of CD14 on monocyte in a dose dependant manner,however,lanthanum chloride could inhibit the increase of CD14 expression on monocytes by halves.Cellular & Molecular Immunology. 2004;1(5):392-394.
基金This work is supported by National Key Basic Research Project （973 program, 2012CB316503） and the National Natural Science Foundation of China （Nos. 31361163004 and 91019016）.
文摘Over the last decade the 3C-based （Chromosome Conformation Capture, 3C） approaches have been developed to describe the frequency of chromatin interaction. The invention of Hi-C allows us to obtain genome-wide chromatin interaction map. However, it is challenging to develop efficient and robust analytical tools to interpret the Hi-C data. Here we present a new method called Clustering based Hi-C Domain Finder （CHDF）, which is based on the difference of interaction intensity inside/outside domains, to identify Hi-C domains. We also compared CHDF with existing methods including Direction Index （DI） and HiCseg. CHDF can define more chromatin domains validated by higher resolution local chromatin structure data （Chromosome Conformation Capture Carbon Copy （5C） data）. Using Hi-C data of lower sequencing depth, chromatin structure identified by CHDF is closer to that discovered by data of higher sequencing depth. Furthermore, the implement of CHDF is faster than the other two. Using CHDF, we are potentially able to discover more hints and clues about chromatin structural elements at domain level.
文摘Dr. Wiedermann commented on our systematic review and meta-regression tbr the sources of heterogeneity in trials reporting H ES 130/0.4 or 0.42 associated excess mortality in septic patients that the pooled analysis of mortality, which showed neither benefit nor harm, might be influenced by trials of low-quality. Statistically, we agree with this conclusion if two of the recruited trials judged as the intermediate risk of bias are precluded.
