Study on Factors Affecting Aerobial Plate Count in Raw Milk

[Objectives]This study was conducted to investigate the main factors affecting the aerobial plate count in raw milk.[Methods]Drinking water,medicated baths and raw milk under different storage and transportation conditions were detected for the values of aerobial plate count to analyze their effects on the aerobial plate count in raw milk.[Results]Disinfection of drinking water tanks could significantly reduce the aerobial plate count in water.The use of medicated baths before and after milking could effectively reduce the aerobial plate count and had a significant bactericidal effect.The growth of microorganisms in raw milk stored below 4℃was relatively slow.Regularly disinfecting drinking water tanks and disinfecting nipples before and after milking could reduce the aerobial plate count in the tanks and nipples.After raw milk was extruded,the temperature should decrease to 0-4℃within 2 h,and the storage time should not exceed 48 h,which could effectively control the aerobial plate count in raw milk.[Conclusions]This study provides a reference for scientific control of the aerobial plate count in raw milk.

Pre- and Post-Surgical Health-Related Quality of Life Evaluation of Esophageal Carcinoma Patients

For patients with esophageal carcinoma (ESCA), health-related quality of life (HRQoL) has now become an essential feature. To examine the quality of life of preoperative and postoperative ESCA patients, we used the European Organization for Research and Treatment of Cancer Quality of Life Core Questionnaire (EORTC QLQ C-30) and the Quality of Life Questionnaire Oesophageal 18 (QLQ-OES18). Using the EORTC QLQ-C30 and the QLQ-OES18 questionnaire, the analysis of the quality of life scores of 246 patients with oesophageal cancer who were operated on at the Sun Yat-sen University Cancer Centre during the period 2013 to 2015 was carried out. Differences between pre- and post-surgical EORTC QLQ C-30 and QLQ-OES18 scores were examined using the Student’s t-test. Patients’ global health status (QoL) decreased significantly one month after the operation but gradually recovered within a year. In terms of the role function, the emotional function, the cognitive function, and the perception and function variants, EORTC QLQ-C30 and QLQ-OES18 scores increased statistically significantly, as did clinical signs variables such as exhaustion, nausea, vomiting, pain, sleeplessness, decreased appetite, stomach pain, and economic hardship. After surgery, there was an improvement in functional and symptom domains in esophageal carcinoma patients. EORTC QLQ-C30 and QLQ-OES18 can be used to assess the HRQoL before and after surgical procedures.

非小细胞肺癌患者肺叶切除术后3 d内发生中重度疼痛风险因素分析

目的:分析非小细胞肺癌患者肺叶切除术后3 d内发生中重度疼痛的风险因素。方法:回顾性分析2020年12月至2021年6月中山大学肿瘤防治中心胸外科行肺叶切除术的非小细胞肺癌患者297例的临床资料。采用数字评定量表对患者术后3 d内每天的最严重疼痛进行评分,疼痛评分 ≥ 4分定义为中重度疼痛。通过二元logistic回归模型分析患者发生术后中重度疼痛的风险因素,以及一般线性模型重复测量方差分析和混合线性模型分析风险因素影响术后疼痛随术后天数的变化趋势。结果:术后当天、第1天、第2天、第3天中重度疼痛发生率分别为34.2%(102/297)、59.8%(178/297)、66.4%(198/297)、28.2%(84/297)。开胸手术患者较胸腔镜手术患者发生中重度疼痛的风险在术后第1天( OR=1.99, P=0.009)、第2天( OR=3.08, P < 0.001)、第3天( OR=3.88, P < 0.001)显著升高,而在术后当天有升高的趋势但差异无统计学意义( OR=1.53, P=0.087)。女性患者较男性患者发生中重度疼痛的风险在术后第2天有升高的趋势( OR=1.62, P=0.077),而在术后第3天显著升高( OR=2.39, P=0.002)。术后预防性使用帕瑞昔布在术后当天 (OR=0.32, P=0.004 )、第1天 (OR=0.20 ,P < 0.001 )、第2天 (OR=0.36, P < 0.001 )和第3天 (OR=0.56,P=0.047 )均可显著降低患者发生中重度疼痛的风险。 结论:非小细胞肺癌患者术后第1天和第2天中重度疼痛的发生率较高。开胸手术患者发生术后中重度疼痛的风险较高,而女性患者在术后第2天和第3天发生中重度疼痛的风险较高。术后预防性使用帕瑞昔布可降低非小细胞肺癌患者发生术后中重度疼痛的风险。