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Early identification of stroke through deep learning with multi-modal human speech and movement data
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作者 Zijun Ou Haitao Wang +9 位作者 Bin Zhang Haobang Liang Bei Hu Longlong Ren yanjuan liu Yuhu Zhang Chengbo Dai Hejun Wu Weifeng Li Xin Li 《Neural Regeneration Research》 SCIE CAS 2025年第1期234-241,共8页
Early identification and treatment of stroke can greatly improve patient outcomes and quality of life.Although clinical tests such as the Cincinnati Pre-hospital Stroke Scale(CPSS)and the Face Arm Speech Test(FAST)are... Early identification and treatment of stroke can greatly improve patient outcomes and quality of life.Although clinical tests such as the Cincinnati Pre-hospital Stroke Scale(CPSS)and the Face Arm Speech Test(FAST)are commonly used for stroke screening,accurate administration is dependent on specialized training.In this study,we proposed a novel multimodal deep learning approach,based on the FAST,for assessing suspected stroke patients exhibiting symptoms such as limb weakness,facial paresis,and speech disorders in acute settings.We collected a dataset comprising videos and audio recordings of emergency room patients performing designated limb movements,facial expressions,and speech tests based on the FAST.We compared the constructed deep learning model,which was designed to process multi-modal datasets,with six prior models that achieved good action classification performance,including the I3D,SlowFast,X3D,TPN,TimeSformer,and MViT.We found that the findings of our deep learning model had a higher clinical value compared with the other approaches.Moreover,the multi-modal model outperformed its single-module variants,highlighting the benefit of utilizing multiple types of patient data,such as action videos and speech audio.These results indicate that a multi-modal deep learning model combined with the FAST could greatly improve the accuracy and sensitivity of early stroke identification of stroke,thus providing a practical and powerful tool for assessing stroke patients in an emergency clinical setting. 展开更多
关键词 artificial intelligence deep learning DIAGNOSIS early detection FAST SCREENING STROKE
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一种基于亚磷酸盐及其脱氢酶的植物磷利用和杂草控制系统的建立 被引量:5
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作者 余桂珍 袁航 +5 位作者 罗著 刘延娟 刘娴 高艳秀 龚明 邹竹荣 《生物工程学报》 CAS CSCD 北大核心 2019年第2期327-336,共10页
磷是植物生长发育所必需的大量营养元素之一。土壤中存在大量的正磷酸盐(Pi),但由于土壤化学和微生物转化使得土壤可利用磷的浓度并不高。土壤缺磷以及杂草的抗除草剂能力已成为当前农业可持续发展的重要限制因素,所以提高植物对土壤磷... 磷是植物生长发育所必需的大量营养元素之一。土壤中存在大量的正磷酸盐(Pi),但由于土壤化学和微生物转化使得土壤可利用磷的浓度并不高。土壤缺磷以及杂草的抗除草剂能力已成为当前农业可持续发展的重要限制因素,所以提高植物对土壤磷的吸收利用能力或寻求可替代正磷酸盐的磷肥以及开发新型杂草控制系统已成为亟待解决的问题。自然界中亚磷酸盐(Phi)是含量仅次于正磷酸盐的磷源,但仅在某些细菌中能被专一性的亚磷酸盐脱氢酶(PTDH)氧化利用,对植物的生长发育则具有抑制作用。利用这一特性,将从土壤宏基因组中直接扩增到的假单胞菌PTDH基因PsPtx通过农杆菌侵染法转入烟草中,并通过RT-PCR、垂直板幼苗生长、显性标记和生长竞争实验分析PsPtx转基因烟草的基因表达以及在Phi胁迫条件下的特性。结果显示,PsPtx在其转基因植株的根茎叶组织中都有几乎相同水平的表达;PsPtx转基因烟草不但能解除Phi对植物的毒害作用,并将它氧化成可用的Pi作为生长发育所需的磷源,而且在Phi胁迫条件下较野生型烟草有相当明显的生长竞争优势;另外PsPtx还具备成为植物遗传转化显性选择标记的优良特质。因此,PsPtx基因编码的亚磷酸盐脱氢酶可用于开发一种基于亚磷酸盐为磷肥和除草剂的植物磷利用和杂草控制系统,为当前农作物转基因研究存在的一些重大问题提供一个有效解决方案。 展开更多
关键词 亚磷酸盐 亚磷酸盐脱氢酶 植物磷利用 杂草控制 选择标记
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