Two-dimensional(2D)topological insulators present a special phase of matter manifesting unique electronic properties.Till now,many monolayer binary compounds of Sb element,mainly with a honeycomb lattice,have been rep...Two-dimensional(2D)topological insulators present a special phase of matter manifesting unique electronic properties.Till now,many monolayer binary compounds of Sb element,mainly with a honeycomb lattice,have been reported as 2D topological insulators.However,research of the topological insulating properties of the monolayer Sb compounds with square lattice is still lacking.Here,by means of the first-principles calculations,a monolayer SbI with square lattice is proposed to exhibit the tunable topological properties by applying strain.At different levels of the strain,the monolayer SbI shows two different structural phases:buckled square structure and buckled rectangular structure,exhibiting attracting topological properties.We find that in the buckled rectangular phase,when the strain is greater than 3.78%,the system experiences a topological phase transition from a nontrivial topological insulator to a trivial insulator,and the structure at the transition point actually is a Dirac semimetal possessing two type-ⅠDirac points.In addition,the system can achieve the maximum global energy gap of 72.5 meV in the topological insulator phase,implying its promising application at room temperature.This study extends the scope of 2D topological physics and provides a platform for exploring the low-dissipation quantum electronics devices.展开更多
Introduction:Observational studies have revealed an association between waist circumference(WC)and atrial fibrillation(AF).However,it is difficult to infer a causal relationship from observational studies because the ...Introduction:Observational studies have revealed an association between waist circumference(WC)and atrial fibrillation(AF).However,it is difficult to infer a causal relationship from observational studies because the observed associations could be confounded by unknown risk factors.Therefore,the causal role of WC in AF is unclear.This study was designed to investigate the causal association between WC and AF using a two-sample Mendelian randomization(MR)analysis.Methods:In our two-sample MR analysis,the genetic variation used as an instrumental variable for MR was acquired from a genome-wide association study(GWAS)of WC(42 single nucleotide polymorphisms with a genetic significance of P<5×10^(-8)).The data of WC(from the Genetic Investigation of ANthropometric Traits consortium,containing 232,101 participants)and the data of AF(from the European Bioinformatics Institute database,containing 55,114 AF cases and 482,295 controls)were used to assess the causal role of WC on AF.Three different approaches(inverse variance weighted[IVW],MR-Egger,and weighted median regression)were used to ensure that our results more reliable.Results:All three MR analyses provided evidence of a positive causal association between high WC and AF.High WC was suggested to increase the risk of AF based on the IVW method(odds ratio[OR]=1.43,95%confidence interval[CI],1.30-1.58,P=2.51×10^(-13)).The results of MR-Egger and weighted median regression exhibited similar trends(MR-Egger OR=1.40[95%CI,1.08-1.81],P=1.61×10^(-2);weighted median OR=1.39[95%CI,1.21-1.61],P=1.62×10^(-6)).MR-Egger intercepts and funnel plots showed no directional pleiotropic effects between high WC and AF.Conclusions:Our findings suggest that greater WC is associated with an increased risk of AF.Taking measures to reduce WC may help prevent the occurrence of AF.展开更多
Background:The ideal blood pressure(BP)target for patients with atrial fibrillation(AF)is still unclear.The present study aimed to assess the effect of the baseline BP on all-cause mortality in patients with AF.Method...Background:The ideal blood pressure(BP)target for patients with atrial fibrillation(AF)is still unclear.The present study aimed to assess the effect of the baseline BP on all-cause mortality in patients with AF.Methods:This registry study included 20 emergency centers across China and consecutively enrolled patients with AF from 2008 to 2011.All participants were followed for 1 year±1 month.The primary endpoint was all-cause mortality.Results:During the follow-up,276(13.9%)all-cause deaths occurred.Kaplan-Meier curves showed that a systolic blood pressure(SBP)110 mmHg or>160 mmHg was associated with a higher risk of all-cause mortality(log-rank test,P=0.014),and a diastolic blood pressure(DBP)<70 mmHg was associated with the highest risk of all-cause mortality(log-rank test,P=0.002).After adjusting for confounders,the multivariable Cox regression model suggested that the risk of all-cause mortality was increased in the group with SBP110 mmHg(hazard ratio[HR],1.963;95%confidence interval[CI],1.306-2.951),and DBP<70 mmHg(HR,1.628;95%CI,1.163-2.281).In the restricted cubic splines,relations between baseline SBP or DBP and all-cause mortality showed J-shaped associations(non-linear P<0.001 and P=0.010,respectively).The risk of all-cause mortality notably increased at a lower baseline SBP and DBP.Conclusions:Having a baseline SBP110 mmHg or DBP<70 mmHg was associated with a significantly higher risk of all-cause mortality in patients with AF.An excessively low BP may not be an optimal target for patients with AF.展开更多
The trivalent lanthanides have been broadly utilized as emitting centers in persistent luminescence(PersL)materials due to their wide emitting spectral range,which thus attract considerable attention over decades.Howe...The trivalent lanthanides have been broadly utilized as emitting centers in persistent luminescence(PersL)materials due to their wide emitting spectral range,which thus attract considerable attention over decades.However,the origin of the trivalent lanthanides’PersL is still an open question,hindering the development of excellent PersL phosphors and their broad applications.Here,the PersL of 12 kinds of the trivalent lanthanides with the exception of La^(3+),Lu^(3+),and Pm^(3+) is reported,and a mechanism of the PersL of the trivalent lanthanides in wide bandgap hosts is proposed.According to the mechanism,the excitons in wide bandgap materials transfer their recombination energy to the trivalent lanthanides that bind the excitons,followed by the generation of PersL.During the PersL process,the trivalent lanthanides as isoelectronic traps bind excitons,and the binding ability is not only related to the inherent arrangement of the 4f electrons of the trivalent lanthanides,but also to the extrinsic ligand field including anion coordination and cation substitution.Our work is believed to be a guidance for designing high-performance PersL phosphors.展开更多
Mechanoluminescent(ML)materials can directly convert external mechanical stimulation into light without the need for excitation from other forms of energy,such as light or electricity.This alluring characteristic make...Mechanoluminescent(ML)materials can directly convert external mechanical stimulation into light without the need for excitation from other forms of energy,such as light or electricity.This alluring characteristic makes ML materials potentially applicable in a wide range of areas,including dynamic imaging of force,advanced displays,information code,storage,and anti-counterfeiting encryption.However,current reproducible ML materials are restricted to sulfide-and oxide-based materials.In addition,most of the reported ML materials require pre-irradiation with ultraviolet(UV)lamps or other light sources,which seriously hinders their practical applications.Here,we report a novel ML material,MgF_(2):Mn^(2+),which emits bright red light under an external dynamic force without the need for pre-charging with UV light.The luminescence properties were systematically studied,and the piezophotonic application was demonstrated.More interestingly,unlike the well-known zinc sulfide ML complexes reported previously,a highly transparent ML film was successfully fabricated by incorporating MgF_(2):Mn^(2+)into polydimethylsiloxane(PDMS)matrices.This film is expected to find applications in advanced flexible optoelectronics such as integrated piezophotonics,artificial skin,athletic analytics in sports.展开更多
In this study,fire tests of four single-section scaled-down utility tunnels were conducted.By analyzing temperature and structural responses of the utility tunnel throughout the fire exposure,the effects on the fire b...In this study,fire tests of four single-section scaled-down utility tunnels were conducted.By analyzing temperature and structural responses of the utility tunnel throughout the fire exposure,the effects on the fire behavior of two different construction methods,cast-in-situ and prefabricated,and of two different materials,ordinary concrete and full lightweight concrete,were explored.The results of the study showed that the shear failure of the cast-in-situ utility tunnel occurred at the end of the top or bottom plate,and the failure of the prefabricated utility tunnel occurred at the junction of the prefabricated member and post-cast concrete.As the temperature increased,the temperature gradient along the thickness direction of the tunnel became apparent.The maximum temperature difference between the inner and outer wall surfaces was 531.7°C.The highest temperature occurred in the cooling stage after stopping the heating,which provided a reference for the fire protection design and rescue of the utility tunnel.The displacement of the top plate of the prefabricated utility tunnel was 16.8 mm,which was 41.8%larger than that of the cast-in-situ utility tunnel.The bearing capacities of the ordinary concrete utility tunnel and full lightweight concrete utility tunnel after the fire loss were 27%and 16.8%,respectively.The full lightweight concrete utility tunnel exhibited good ductility and fire resistance and high collapse resistance.展开更多
基金Supported by the National Natural Science Foundation of China(Grant Nos.11974076 and 61804030)the Key Project of Natural Science Foundation of Fujian Province(Grant No.2021J02012)。
文摘Two-dimensional(2D)topological insulators present a special phase of matter manifesting unique electronic properties.Till now,many monolayer binary compounds of Sb element,mainly with a honeycomb lattice,have been reported as 2D topological insulators.However,research of the topological insulating properties of the monolayer Sb compounds with square lattice is still lacking.Here,by means of the first-principles calculations,a monolayer SbI with square lattice is proposed to exhibit the tunable topological properties by applying strain.At different levels of the strain,the monolayer SbI shows two different structural phases:buckled square structure and buckled rectangular structure,exhibiting attracting topological properties.We find that in the buckled rectangular phase,when the strain is greater than 3.78%,the system experiences a topological phase transition from a nontrivial topological insulator to a trivial insulator,and the structure at the transition point actually is a Dirac semimetal possessing two type-ⅠDirac points.In addition,the system can achieve the maximum global energy gap of 72.5 meV in the topological insulator phase,implying its promising application at room temperature.This study extends the scope of 2D topological physics and provides a platform for exploring the low-dissipation quantum electronics devices.
基金supported by grants from the National Natural Science Foundation of China Grant Awards(No.81960669)The National High Level Hospital Clinical Research Funding(No.2022-GSP-GG-22)+1 种基金Capital’s Funds for Research and Application of Clinical Diagnosis and Treatment Technology(No.Z191100006619121)National Clinical Research Center for Cardiovascular Diseases,Fuwai Hospital,Chinese Academy of Medical Sciences(No.NCRC2020015)
文摘Introduction:Observational studies have revealed an association between waist circumference(WC)and atrial fibrillation(AF).However,it is difficult to infer a causal relationship from observational studies because the observed associations could be confounded by unknown risk factors.Therefore,the causal role of WC in AF is unclear.This study was designed to investigate the causal association between WC and AF using a two-sample Mendelian randomization(MR)analysis.Methods:In our two-sample MR analysis,the genetic variation used as an instrumental variable for MR was acquired from a genome-wide association study(GWAS)of WC(42 single nucleotide polymorphisms with a genetic significance of P<5×10^(-8)).The data of WC(from the Genetic Investigation of ANthropometric Traits consortium,containing 232,101 participants)and the data of AF(from the European Bioinformatics Institute database,containing 55,114 AF cases and 482,295 controls)were used to assess the causal role of WC on AF.Three different approaches(inverse variance weighted[IVW],MR-Egger,and weighted median regression)were used to ensure that our results more reliable.Results:All three MR analyses provided evidence of a positive causal association between high WC and AF.High WC was suggested to increase the risk of AF based on the IVW method(odds ratio[OR]=1.43,95%confidence interval[CI],1.30-1.58,P=2.51×10^(-13)).The results of MR-Egger and weighted median regression exhibited similar trends(MR-Egger OR=1.40[95%CI,1.08-1.81],P=1.61×10^(-2);weighted median OR=1.39[95%CI,1.21-1.61],P=1.62×10^(-6)).MR-Egger intercepts and funnel plots showed no directional pleiotropic effects between high WC and AF.Conclusions:Our findings suggest that greater WC is associated with an increased risk of AF.Taking measures to reduce WC may help prevent the occurrence of AF.
基金supported by Capital’s Funds for Research and Application of Clinical Diagnosis and Treatment Technology(Z191100006619121)High-level Hospital Clinical Research Funds(2022-GSP-GG-26)
文摘Background:The ideal blood pressure(BP)target for patients with atrial fibrillation(AF)is still unclear.The present study aimed to assess the effect of the baseline BP on all-cause mortality in patients with AF.Methods:This registry study included 20 emergency centers across China and consecutively enrolled patients with AF from 2008 to 2011.All participants were followed for 1 year±1 month.The primary endpoint was all-cause mortality.Results:During the follow-up,276(13.9%)all-cause deaths occurred.Kaplan-Meier curves showed that a systolic blood pressure(SBP)110 mmHg or>160 mmHg was associated with a higher risk of all-cause mortality(log-rank test,P=0.014),and a diastolic blood pressure(DBP)<70 mmHg was associated with the highest risk of all-cause mortality(log-rank test,P=0.002).After adjusting for confounders,the multivariable Cox regression model suggested that the risk of all-cause mortality was increased in the group with SBP110 mmHg(hazard ratio[HR],1.963;95%confidence interval[CI],1.306-2.951),and DBP<70 mmHg(HR,1.628;95%CI,1.163-2.281).In the restricted cubic splines,relations between baseline SBP or DBP and all-cause mortality showed J-shaped associations(non-linear P<0.001 and P=0.010,respectively).The risk of all-cause mortality notably increased at a lower baseline SBP and DBP.Conclusions:Having a baseline SBP110 mmHg or DBP<70 mmHg was associated with a significantly higher risk of all-cause mortality in patients with AF.An excessively low BP may not be an optimal target for patients with AF.
基金L.L.thanks the support from the Advanced Talents Incubation Program of Hebei University(521100221006)Y.Y.acknowledges the financial support from the National Natural Science Foundation of China(11974097)+1 种基金the Natural Science Foundation of Hebei Province(A2019201073)J.Q.acknowledges the support from the National Natural Science Foundation of China(52161135109).
文摘The trivalent lanthanides have been broadly utilized as emitting centers in persistent luminescence(PersL)materials due to their wide emitting spectral range,which thus attract considerable attention over decades.However,the origin of the trivalent lanthanides’PersL is still an open question,hindering the development of excellent PersL phosphors and their broad applications.Here,the PersL of 12 kinds of the trivalent lanthanides with the exception of La^(3+),Lu^(3+),and Pm^(3+) is reported,and a mechanism of the PersL of the trivalent lanthanides in wide bandgap hosts is proposed.According to the mechanism,the excitons in wide bandgap materials transfer their recombination energy to the trivalent lanthanides that bind the excitons,followed by the generation of PersL.During the PersL process,the trivalent lanthanides as isoelectronic traps bind excitons,and the binding ability is not only related to the inherent arrangement of the 4f electrons of the trivalent lanthanides,but also to the extrinsic ligand field including anion coordination and cation substitution.Our work is believed to be a guidance for designing high-performance PersL phosphors.
基金financial support from the Advanced Talents Incubation Program of Hebei University (521100221006)financial support from the National Natural Science Foundation of China (11974097)+2 种基金the Natural Science Foundation of Hebei Province (A2019201073)support from the National Natural Science Foundation of China (61875136)the Fundamental Research Project of Guangdong Province (2020A1515011315)
文摘Mechanoluminescent(ML)materials can directly convert external mechanical stimulation into light without the need for excitation from other forms of energy,such as light or electricity.This alluring characteristic makes ML materials potentially applicable in a wide range of areas,including dynamic imaging of force,advanced displays,information code,storage,and anti-counterfeiting encryption.However,current reproducible ML materials are restricted to sulfide-and oxide-based materials.In addition,most of the reported ML materials require pre-irradiation with ultraviolet(UV)lamps or other light sources,which seriously hinders their practical applications.Here,we report a novel ML material,MgF_(2):Mn^(2+),which emits bright red light under an external dynamic force without the need for pre-charging with UV light.The luminescence properties were systematically studied,and the piezophotonic application was demonstrated.More interestingly,unlike the well-known zinc sulfide ML complexes reported previously,a highly transparent ML film was successfully fabricated by incorporating MgF_(2):Mn^(2+)into polydimethylsiloxane(PDMS)matrices.This film is expected to find applications in advanced flexible optoelectronics such as integrated piezophotonics,artificial skin,athletic analytics in sports.
基金The research was financially supported by the Jilin Provincial Department of Science and Technology Key Research and Development Project(20200403071SF)National Emergency Management Department Safety Accident Prevention Science and Technology Project(Jilin-0001-2018AQ).
文摘In this study,fire tests of four single-section scaled-down utility tunnels were conducted.By analyzing temperature and structural responses of the utility tunnel throughout the fire exposure,the effects on the fire behavior of two different construction methods,cast-in-situ and prefabricated,and of two different materials,ordinary concrete and full lightweight concrete,were explored.The results of the study showed that the shear failure of the cast-in-situ utility tunnel occurred at the end of the top or bottom plate,and the failure of the prefabricated utility tunnel occurred at the junction of the prefabricated member and post-cast concrete.As the temperature increased,the temperature gradient along the thickness direction of the tunnel became apparent.The maximum temperature difference between the inner and outer wall surfaces was 531.7°C.The highest temperature occurred in the cooling stage after stopping the heating,which provided a reference for the fire protection design and rescue of the utility tunnel.The displacement of the top plate of the prefabricated utility tunnel was 16.8 mm,which was 41.8%larger than that of the cast-in-situ utility tunnel.The bearing capacities of the ordinary concrete utility tunnel and full lightweight concrete utility tunnel after the fire loss were 27%and 16.8%,respectively.The full lightweight concrete utility tunnel exhibited good ductility and fire resistance and high collapse resistance.