Background:This study aimed to evaluate the diagnostic accuracy of magnetocardiograph,a relatively new noninvasive device,in patients with myocardial infarction(MI).Methods:To identify studies assessing the diagnostic...Background:This study aimed to evaluate the diagnostic accuracy of magnetocardiograph,a relatively new noninvasive device,in patients with myocardial infarction(MI).Methods:To identify studies assessing the diagnostic accuracy of magnetocardiography for MI,we searched four databases on November 7,2022,the Cochrane Central Register of Controlled Trials,MEDLINE,EMBASE,and Web of Science,plus ClinicalTrials.gov.Three reviewers screened the studies independently and emailed the authors for more precise data when necessary.The Quality Assessment of Diagnostic Accuracy Studies 2 tool was used to evaluate the quality of the included studies.STATA(version 17;Stata Corporation,College Station,TX,USA)was used for meta-analysis of 22 contingency table data.Results:A total of 6 articles were included in this study.The diagnostic parameters of all included studies were summarized as follows:the pooled sensitivity was 0.91(95%confidence intervals[95%CIs]:0.81–0.96;I 2=88.54);specificity was 0.83(95%CI:0.75–0.89;I 2=83);positive likelihood ratio was 5.3(95%CI:3.5–8.2);negative likelihood ratio was 0.1(95%CI:0.04–0.24);and diagnostic odds ratio was 51(95%CI:16–161).The area under the curve for the receiver operating characteristic curve was 0.92(95%CI:0.89–0.94).After metaregression analysis,we found that the number of channels and the way of environmental magnetic noise elimination were heterogeneous sources.Conclusion:In summary,our meta-analysis shows that magnetocardiography holds a high accuracy in diagnosing MI and takes the advantages of noninvasive,radiation-free,and noncontact.However,further high-quality studies to confirm its usefulness in diagnosing MI are warranted.展开更多
基金supported by the National Key R&D Program of China(2020YFC1512700,2020YFC1512705,and 2020YFC1512703)National Science and Technology Fundamental Resources Investigation Project(2018FY100600 and 2018FY100602)+4 种基金Key R&D Program of Shandong Province(2021ZLGX02,2021SFGC0503,and 2022ZLGX03)Taishan Pandeng Scholar Program of Shandong Province(tspd20181220)Taishan Young Scholar Program of Shandong Province(tsqn202211312)the Interdisciplinary Young Researcher Groups Program of Shandong University(2020QNQT004)Youth Top-Talent Project of National Ten Thousand Talents Plan,and Qilu Young Scholar Program.
文摘Background:This study aimed to evaluate the diagnostic accuracy of magnetocardiograph,a relatively new noninvasive device,in patients with myocardial infarction(MI).Methods:To identify studies assessing the diagnostic accuracy of magnetocardiography for MI,we searched four databases on November 7,2022,the Cochrane Central Register of Controlled Trials,MEDLINE,EMBASE,and Web of Science,plus ClinicalTrials.gov.Three reviewers screened the studies independently and emailed the authors for more precise data when necessary.The Quality Assessment of Diagnostic Accuracy Studies 2 tool was used to evaluate the quality of the included studies.STATA(version 17;Stata Corporation,College Station,TX,USA)was used for meta-analysis of 22 contingency table data.Results:A total of 6 articles were included in this study.The diagnostic parameters of all included studies were summarized as follows:the pooled sensitivity was 0.91(95%confidence intervals[95%CIs]:0.81–0.96;I 2=88.54);specificity was 0.83(95%CI:0.75–0.89;I 2=83);positive likelihood ratio was 5.3(95%CI:3.5–8.2);negative likelihood ratio was 0.1(95%CI:0.04–0.24);and diagnostic odds ratio was 51(95%CI:16–161).The area under the curve for the receiver operating characteristic curve was 0.92(95%CI:0.89–0.94).After metaregression analysis,we found that the number of channels and the way of environmental magnetic noise elimination were heterogeneous sources.Conclusion:In summary,our meta-analysis shows that magnetocardiography holds a high accuracy in diagnosing MI and takes the advantages of noninvasive,radiation-free,and noncontact.However,further high-quality studies to confirm its usefulness in diagnosing MI are warranted.
