Modularized and Parametric Modeling Technology for Finite Element Simulations of Underground Engineering under Complicated Geological Conditions

The surrounding geological conditions and supporting structures of underground engineering are often updated during construction,and these updates require repeated numerical modeling.To improve the numerical modeling efficiency of underground engineering,a modularized and parametric modeling cloud server is developed by using Python codes.The basic framework of the cloud server is as follows:input the modeling parameters into the web platform,implement Rhino software and FLAC3D software to model and run simulations in the cloud server,and return the simulation results to the web platform.The modeling program can automatically generate instructions that can run the modeling process in Rhino based on the input modeling parameters.The main modules of the modeling program include modeling the 3D geological structures,the underground engineering structures,and the supporting structures as well as meshing the geometric models.In particular,various cross-sections of underground caverns are crafted as parametricmodules in themodeling program.Themodularized and parametric modeling program is used for a finite element simulation of the underground powerhouse of the Shuangjiangkou Hydropower Station.This complicatedmodel is rapidly generated for the simulation,and the simulation results are reasonable.Thus,this modularized and parametric modeling program is applicable for three-dimensional finite element simulations and analyses.

Weak and Strong Convergence of Self Adaptive Inertial Subgradient Extragradient Algorithms for Solving Variational Inequality Problems

Many solutions of variational inequalities have been proposed,among which the subgradient extragradient method has obvious advantages.Two different algorithms are given for solving variational inequality problem in this paper.The problem we study is defined in a real Hilbert space and has L-Lipschitz and pseudomonotone condition.Two new algorithms adopt inertial technology and non-monotonic step size rule,and their convergence can still be proved when the value of L is not given in advance.Finally,some numerical results are designed to demonstrate the computational efficiency of our two new algorithms.

四川大学博物馆结构设计重难点分析研究

四川大学博物馆采用钢框架结构体系,并设置屈曲约束支撑改善结构的抗震性能。介绍了四川大学博物馆的结构设计参数及抗震性能目标。针对结构设计中的重难点,开展了屈曲约束支撑的工作机理分析、框架柱计算长度与穿层柱分析、东侧大悬挑空间的相关分析。利用反应谱分析及时程分析探究了屈曲约束支撑工作机理,分析结果表明,屈曲约束支撑能够有效改善钢结构产生塑性铰的状况,起到保护主体钢框架的作用。针对东侧大悬挑空间的功能要求,设计采用了屋顶桁架结合钢拉杆吊挂东侧大楼梯的结构形式,通过结构防连续倒塌分析、楼板应力分析、楼盖舒适度分析、关键节点有限元分析等确保该部位结构设计安全合理。对整体结构受力机理和薄弱部位进行了研究,提出了重点部位的设计原则和加强措施。

强宿根高产高糖甘蔗新品种云蔗101666的选育与评价

【目的】适应蔗糖产业发展的需求,选育宿根性好的高产高糖甘蔗新品种,保障蔗农和糖企利益,为云南和中国蔗糖产业的可持续发展提供品种支持。【方法】以‘桂糖96-167’为母本、‘崖城93-26’为父本进行甘蔗有性杂交,通过“五圃制”选育程序,经区试试验综合考察‘云蔗101666’的形态特征和生产性状。【结果】‘云蔗101666’蔗茎均匀,株型紧凑直立,中至中大茎,脱叶性好;2017—2019年区试试验中11—3月的蔗糖分分别为:12.80%、14.97%、16.26%、17.09%、17.37%,全期平均蔗糖分达15.46%,比‘新台糖22号’高出0.71个百分点;平均蔗茎产量121.32 t/hm^(2),较‘新台糖22号’增产22.50%;平均糖产量18.67 t/hm^(2),比‘新台糖22号’增产29.20%。该品种中抗黑穗病和条纹花叶病,感高粱花叶病,于2020年7月获植物新品种权。【结论】‘云蔗101666’为中早熟、高产、高糖品种,其抗旱性强,宿根性好,脱叶性佳,适宜在云南德宏、版纳、临沧、富宁蔗区海拔900~1400 m甘蔗产区中等以上肥力的的旱坡地、台地种植。

油气资产折耗与PD储量关系及管控措施研究

随着勘探开发不断深入,油气田企业完全成本呈逐年上升趋势,而油气资产折耗在完全成本中占比高达50%左右,降低完全成本的关键在于管控折耗。证实已开发(Proved Developed,PD)储量是油气资产折耗计提基础,主要通过折耗影响完全成本。从油气资产折耗的影响因素入手,深入挖潜折耗、操作成本、油气资产净额、产量等因素与PD储量之间的量化关联关系。通过实例分析,对不同区块开展折耗—PD储量—操作成本敏感性分析,建立折耗定量分配模型,针对性提出具体折耗管控措施,实现折耗计提与储量评估之间的科学有效联动。研究结果为油气田企业超前部署储量评估、管控油气资产折耗,降低完全成本,优化油气资产结构提供了策略建议。

老年经皮冠状动脉介入治疗术后患者出院计划护理方案的构建研究

目的:建立老年经皮冠状动脉介入治疗术后患者出院计划护理方案,旨在提高出院计划的实施效果。方法:经文献检索,整合出院计划护理方案并制定专家咨询问卷,应用德尔菲法由16名专家对问卷进行两次咨询。结果:专家权威系数为0.897,两次专家咨询结束后,最终形成了包括5项Ⅰ级指标、15项Ⅱ级指标和60项Ⅲ级指标的出院计划护理方案,各指标重要性赋值平均4.00~4.75,变异系数0.09~0.19,操作性平均值为4.00~4.88,变异系数为0.07~0.19。结论:构建的老年经皮冠状动脉介入术后患者出院计划护理方案内容全面、可靠,具有较好的科学性和实用性,可为患者出院计划的实施提供参考。

Mass transfer mechanism and relationship of gas–liquid annular flow in a microfluidic cross-junction device

Mass transfer performance of gas–liquid two-phase flow at microscale is the basis of application of microreactor in gas–liquid reaction systems.At present,few researches on the mass transfer property of annular flow have been reported.Therefore,the mass transfer mechanism and relationship of gas–liquid annular flow in a microfluidic cross-junction device are studied in the present study.We find that the main factors,i.e.,flow pattern,liquid film thickness,liquid hydraulic retention time,phase interface fluctuation,and gas flow vorticity,which influence the flow mass transfer property,are directly affected both by gas and liquid flow velocities.But the influences of gas and liquid velocities on different mass transfer influencing factors are different.Thereout,the fitting relationships between gas and liquid flow velocities and mass transfer influencing factors are established.By comparing the results from calculations using fitting equations and simulations,it shows that the fitting equations have relatively high degrees of accuracy.Finally,the Pareto front,namely the Pareto optimal solution set,of gas and liquid velocity conditions for the best flow mass transfer property is obtained using the method of multi-objective particle swarm optimization.It is proved that the mass transfer property of the gas–liquid two-phase flow can be obviously enhanced under the guidance of the obtained Pareto optimal solution set through experimental verification.

Endemic medicinal plant distribution correlated with stable climate,precipitation,and cultural diversity

Medicinal plants provide crucial ecosystem services,especially in developing countries such as China,which harbors diverse endemic medicinal plant species with substantial cultural and economic value.Accordingly,understanding the patterns and drivers of medicinal plant distribution is critical.However,few studies have investigated the patterns and drivers of endemic medicinal plants distribution in China.Here,we linked endemic medicinal plants distribution with possible explanatory variables,i.e.,paleoclimate change,contemporary climate,altitudinal range and ethnic minority human population size at the prefecture city level in China.Our results show that endemic medicinal plants are concentrated in southern China,especially in southwestern China.Notably,both endemic medicinal plant species richness and the ratio of endemic medicinal plant species richness are negatively associated with glacialinterglacial anomaly in temperature,and positively associated with contemporary precipitation and altitudinal range.In addition,we found that endemic medicinal plant species richness is positively associated with ethnic minority population sizes as well as its ratio to the overall population size.These findings suggest that the distribution of endemic medicinal plants is determined by multiple drivers.Furthermore,our findings stress that dramatic future climate changes and massive anthropogenic activities in southern China pose great challenges to the conservation of China's endemic medicinal plants.

全媒体视域下高校心理育人实践路径探究

文章基于全媒体视域,多角度分析当前高校心理育人所面临的现实困境,主要包括高校心理育人队伍体系薄弱、心理育人实践过程衔接度不高、心理育人实践成效较低等。同时全媒体的大环境也为高校心理育人工作带来了新的机遇,为高校心理育人工作提供了更多渠道和手段、更广泛的空间和资源、更多的互动和参与机会以及更多的数据和信息,促进了高校心理育人队伍的专业成长。基于此,文章提出全媒体视域下高校心理育人实践路径:发挥课堂主渠道,打造全方位的心理育人课程体系;促进资源整合,构建多元化的心理育人实践平台;挖掘朋辈力量,发挥朋辈的心理育人作用;构建家校共育机制,助力大学生心理健康教育。

A laser-produced plasma source based on thin-film Gd targets for next-generation extreme ultraviolet lithography

We have studied laser-produced plasma based on mass-limited thin-film Gd targets for beyond the current extreme ultraviolet(EUV)light source of 13.5 nm wavelength based on tin.The influences of the laser intensity on the emission spectra centered around 6.7 nm from thin-film Gd targets were first investigated.It is found that the conversion efficiency of the produced plasma is saturated when the laser intensity goes beyond 2×10^(11)W cm^(-2).We have systematically compared the emission spectra of the laser-produced plasma with the changes in the thicknesses of the thin-film Gd targets.It is proved that a minimum-mass target with a thickness of 400 nm is sufficient to provide the maximum conversion efficiency,which also implies that this thickness is the ablation depth for the targets.These findings should be helpful in the exploration of next-generation EUV sources,as the thin-film Gd targets will reduce the debris during the plasma generation process compared with the bulk targets.

Theanine combined with cisplatin inhibits the proliferation and metastasis of TNBC cells through Akt signaling pathway

Background:Theanine,was natural compounds,has been employed in antibacterial,antineoplastic,promotion of hair growth,therapy of poliosis,and removing pattogenic heat from the blood and toxic material from the body for centuries.However,few reports focused on the treatment by theanine combined with chemotherapy in triple negative breast cancer.Methods:Our study aimed to evaluate and compare the molecular and cellular effects of theanine in combination with cisplatin in triple negative breast cancer lines MDA-MB-231.The 50%inhibitory concentration and cell viability were determined by the cell counting kit-8 assay.Meanwhile,wound healing and transwell assays were used to evaluate the effect of theanine combination with cisplatin on triple negative breast cancer(TNBC)cell metastasis.Moreover,the label-free proteomic method was available to explore the molecular mechanism of theanine combination with cisplatin on TNBC cells.What’s more,reverse transcription-polymerase chain reaction and western blotting were carried out to evaluate the related protein and mRNA alteration in the Akt signaling pathway.Results:With theanine added,the inhibitory effect of cisplatin on cell proliferation and metastasis was significantly improved.Meanwhile,with the increase of theanine concentration,the anti-tumor effect of the combination group was also significantly improved.Afterward,label-free proteomics analysis showed that theanine combined with cisplatin could significantly activate the Akt signaling pathway,thus improving the anti-tumor effect of cisplatin.Finally,reverse transcription-polymerase chain reaction and western blotting experiment showed that the combination of cisplatin with theanine induced the greatest down-regulation of phosphorylated Akt expression.Conclusion:All in all,combining theanine with appears to be a promising strategy for the effective treatment of TNBC in the prospective application which merits further clinical investigation.

皖豫高效抗逆大豆根瘤菌Y2-4的选育

为筛选适合安徽、河南两地的大豆高效抗逆根瘤菌,从安徽和河南两地选取7个采样点采集大豆根瘤并分离根瘤菌,通过系统发育分子鉴定、回接大豆筛选、抗逆境胁迫能力测定筛选高效抗逆大豆根瘤菌,并通过初步田间接种试验对其促生效果进行了评估。结果显示:共分离得到621株大豆根瘤细菌,其中Sinorhizobium属菌株418株(67.3%),是该地区的优势大豆根瘤菌,Bradyrhizobium属菌株198株(31.9%),Rhizobium属菌株5株(0.8%,回接大豆不能结瘤)。筛选得到1株具有应用潜力的高效抗逆根瘤菌S.fredii Y2-4,与参比菌株CCBAU 45436相比,Y2-4菌株接种的大豆叶绿素含量、根瘤数、地上干重分别提高了1.8%、15.5%和9.8%,且在3%NaCl盐胁迫及38℃高温胁迫条件下仍具有生长能力。田间接种试验结果显示,在全氮(225 kg·hm^(-2)复合肥,氮磷钾比例15∶15∶15)、减氮26.6%(225 kg·hm^(-2)复合肥,氮磷钾比例11∶15∶15)、不施氮(225 kg·hm^(-2)复合肥,氮磷钾比例0∶15∶15)3种氮肥水平下接种Y2-4菌株均可以提高大豆产量,“减氮26.6%+接种Y2-4”处理较“全氮+不接种”处理条件下,大豆产量增加了25.5%。综上所述,Y2-4菌株可以作为皖豫两省部分地区的大豆高效抗逆根瘤菌接种菌株进行推广应用。

交流配电网分布鲁棒优化模型及快速求解算法

针对鲁棒优化保守性大、求解困难的缺点,本文提出交流配电网两阶段分布鲁棒优化模型及其快速求解算法。该模型以开关操作成本、微型燃气轮机发电成本、网损成本及弃风弃光切负荷成本最小为目标函数,构建基于置信区间的两阶段分布鲁棒优化模型;然后以电压的平方和相角为独立变量,提出变量替换结合二阶锥变换的模型转换新方法,将原模型转换为易于求解的混合整数二阶锥规划模型。算例分析表明,本文所提模型克服了基于盒式不确定集的鲁棒优化模型保守大的缺点,提高了算法求解速度。

高产抗逆甘蔗新品种云蔗102768的选育

【目的】针对甘蔗生产上需要解决的问题,选育高产、高糖、抗旱、抗病的甘蔗新品种,为甘蔗产业的可持续发展提供重要支撑。【方法】以‘新台糖26号’为母本、‘新台糖11号’为父本进行甘蔗有性杂交,采用甘蔗“五圃制”选育程序,经过各级圃筛选、区试试验评比分析,选育出优良甘蔗新品种‘云蔗102768’。【结果】‘云蔗102768’中晚熟、高产、高糖、中-中大茎,脱叶性好、抗旱性强,高抗黑穗病、中抗条纹花叶病、抗高粱花叶病。在云南省第十五轮甘蔗新品种区域化试验中,平均蔗产量122.17 t/hm^(2),比对照‘新台糖22号’(下同)增产13.3%;全期(11月—次年3月)平均蔗糖分14.70%,与对照相当;平均含糖量16.26 t/hm^(2),比对照增产12.4%。【结论】该品种于2022年通过中华人民共和国农业农村部非主要农作物品种登记[登记编号:GPD甘蔗(2022)530004],适宜在云南省临沧、德宏、保山、红河等蔗区中等以上肥力的水田、坝地和有灌溉条件的坡地、台地种植。

基于三角芳香配体的金属有机框架对染料木素的吸附性能与机理

目的:提高染料木素的吸附率。方法:采用水热法合成2种含不同尺寸三角芳香配体的MOFs(MOF-808和PCN-777),通过系列表征确定MOFs的合成,比较其与线性二元羧酸配体构筑的MOF(UiO-66)对染料木素的吸附效果;考察孔隙特征、疏水性变化等对吸附性能的影响,利用X射线光电子能谱探究其吸附机理。结果:与线性配体构筑的UiO-66相比,三角芳香配体构筑的MOFs(MOF-808和PCN-777)的孔径分别从0.65 nm增大到1.81,3.55 nm,水接触角分别从47.91°增大到110.68°,128.23°。线性配体构筑的UiO-66对染料木素的吸附量为40.08 mg/g,吸附率为39.98%;而三角芳香配体构筑的MOFs(MOF-808和PCN-777)对染料木素的吸附量分别为61.80,81.75 mg/g,吸附率分别为61.63%,81.52%。结论:金属有机框架可用于染料木素的吸附富集,相较于线性配体,引入不同尺寸的三角芳香配体改变了MOFs孔径及疏水性,加强了MOFs的内部可及性并提供了更多吸附位点,从而提高了对染料木素的吸附效果。PCN-777对染料木素的吸附机理为金属螯合作用、π-π相互作用和疏水相互作用的协同。

基于加速康复外科理念的护理干预在腹腔镜胆囊切除术患者围手术期的应用效果

目的 探讨基于加速康复外科(ERAS)理念的护理干预在腹腔镜胆囊切除术(LC)患者围手术期的应用效果。方法 选取2021年1月至2022年3月河北省邯郸市中心医院接受LC治疗的100例患者为研究对象,采用随机数字表法将其分为常规组和干预组,各50例。常规组实施常规围手术期护理,干预组在常规组的基础上行ERAS理念下围手术期护理。观察并比较两组应激反应指标水平变化、术后疼痛程度、并发症发生情况及患者术后康复速度。结果 术后24 h,两组皮质醇、肾上腺素水平均高于术前1 h,且干预组术前1 h、术后24 h时指标水平低于常规组,差异有统计学意义(P<0.05);干预组术后视觉模拟评分法评分、并发症总发生率低于常规组,差异有统计学意义(P<0.05);干预组术后首次下床、肛门首次排气、首次排便、停止输液及住院时间均短于常规组,差异有统计学意义(P<0.05)。结论 基于ERAS理念围手术期干预模式用于LC治疗患者,可避免患者出现强烈应激反应,缓解疼痛感,预防并发症发生,缩短患者术后康复时间。

慢性阻塞性肺疾病病人吸入治疗管理的最佳证据总结

目的:总结慢性阻塞性肺疾病病人吸入治疗管理最佳证据,为临床医护人员及居家慢性阻塞性肺疾病病人吸入治疗提供科学依据。方法:检索与慢性阻塞性肺疾病吸入治疗相关的指南、专家共识或专家意见、证据总结、系统评价,然后由经过循证课程培训的研究人员对纳入的文献进行质量评价,根据专业知识判断提取和整合证据,形成最佳证据总结。结果:最终纳入指南10篇,专家共识7篇,证据总结1篇,共18篇文献,从吸入剂装置的选择、吸入剂药物选择、吸入剂治疗后管理、雾化吸入方式的选择、雾化吸入药物指导、雾化吸入过程中管理、无创通气与雾化之间的影响、雾化吸入后管理8个方面形成了33条最佳证据。结论:慢性阻塞性肺疾病病人吸入治疗管理的最佳证据为临床正确实施雾化吸入操作的医护人员和病人及其照护者提供了循证依据。

乐山市不同年龄段女性泌尿生殖道支原体检出情况及耐药性分析

目的分析四川省乐山市不同年龄段女性患者泌尿生殖道支原体检出情况及其对抗菌药物的耐药性,为该地区女性泌尿生殖道支原体感染的诊断和治疗提供依据。方法回顾性分析2020年9月—2022年10月四川省乐山人民医院妇科和皮肤科诊治疑似为女性泌尿生殖道感染的1064例标本的支原体培养和药敏结果。结果1064例标本中支原体培养阳性率为53.75%(572/1064),主要集中在21~30岁及31~40岁两个年龄段,分别占20.21%(215/1064)和17.48%(186/1064),各年龄阶段的阳性检出率有统计学意义(P<0.01)。在阳性检出例数中,单纯解脲脲原体(Uu)阳性检出率44.36%(472/1064),单纯人型支原体(Mh)阳性检出率0.56%(6/1064),Uu和Mh混合检出率为8.83%(94/1064)。单纯Uu对交沙霉素、多西环素、米诺环素和四环素敏感率达到94.07%以上,对氧氟沙星、环丙沙星、左氧氟沙星和司帕沙星敏感率低于12.92%;单纯Mh对多西环素、米诺环素、交沙霉素和四环素敏感率均达到100.0%,对其余药物敏感率低于33.33%;Uu和Mh混合对多西环素、米诺环素和交沙霉素的敏感率高于86.17%,对四环素敏感率为73.40%,对其余药物敏感率均低于5.32%。结论四川乐山地区女性泌尿生殖道支原体以单纯Uu检出率最高,Uu和Mh混合检出率次之,单纯Mh检出率最低。21~30岁及31~40岁两个年龄段是感染的高发人群。支原体对多西环素、米诺环素和交沙霉素敏感,对氧氟沙星、左氧氟沙星和环丙沙星耐药严重。临床应根据感染类型的不同及抗菌药物的敏感性,合理选用抗菌药物。

近红外漫反射光谱法快速检测高纤维素、木质素物料水分含量

目的:建立一种快速检测高纤维素、木质素物料水分含量的方法。方法:以槟榔这种含高纤维素、木质素的中药材为原料,用近红外光谱仪采集近红外漫反射光谱,运用NIR Cal建模软件对光谱数据进行预处理,优选特征波长,并运用偏最小二乘法(PLS)分析建立槟榔水分含量定量模型。结果:槟榔水分含量定量模型校正集决定系数为0.9942,校正误差均方根(RMSEC)为0.50;验证集决定系数为0.9867,预测误差均方根(RMSEP)为0.68。结论:该方法简便、快速、安全、实用、准确,适用于含高纤维素、木质素物料的水分含量的快速测定。

新媒体时代高校心理委员培养模式探究——基于积极心理学视域

随着新媒体时代的到来,高校心理委员的作用变得愈发重要。作为学校心理健康教育网络的重要组成部分,心理委员要具备相关的心理健康知识和技能,关注同学们的心理健康状况,及时发现和解决同学们的心理健康问题。文章从积极心理学视域出发,探讨在新媒体时代如何培养具备积极心态、良好职业道德和自我保健能力的高校心理委员。积极心理学将关注点从负面心理现象转向正面、积极的心理现象,通过培养心理委员的积极心态,保证其在遇到问题时能够正确处理,不被负面情绪干扰。新媒体手段不断丰富,为心理委员提供了更多的学习资源和交流平台。心理委员经过系统培训后,可以不断提升心理学相关知识储备和技能。随着新媒体的飞速发展,心理健康知识的宣传更加生动化、便捷化。新媒体扩大了宣传工作的影响力,提高了心理数据收集效率,增强了交流沟通的便捷性。高校心理委员可以通过学生的反馈、定期评估、团队内部探讨了解自己的不足之处,从而作出针对性的调整和改进。新媒体时代,积极心理学为培养高校心理委员提供了新的视角和策略。通过系统培训、合理干预和有效反馈等措施,可以构建一个全面且有效的高校心理委员培养模式,为完善高校心理健康教育提供新的思路和方法。