We present a time domain hybrid method to realize the fast coupling analysis of transmission lines excited by space electromagnetic fields, in which parallel finite-difference time-domain (FDTD) method, interpolation ...We present a time domain hybrid method to realize the fast coupling analysis of transmission lines excited by space electromagnetic fields, in which parallel finite-difference time-domain (FDTD) method, interpolation scheme, and Agrawal model-based transmission line (TL) equations are organically integrated together. Specifically, the Agrawal model is employed to establish the TL equations to describe the coupling effects of space electromagnetic fields on transmission lines. Then, the excitation fields functioning as distribution sources in TL equations are calculated by the parallel FDTD method through using the message passing interface (MPI) library scheme and interpolation scheme. Finally, the TL equations are discretized by the central difference scheme of FDTD and assigned to multiple processors to obtain the transient responses on the terminal loads of these lines. The significant feature of the presented method is embodied in its parallel and synchronous calculations of the space electromagnetic fields and transient responses on the lines. Numerical simulations of ambient wave acting on multi-conductor transmission lines (MTLs), which are located on the PEC ground and in the shielded cavity respectively, are implemented to verify the accuracy and efficiency of the presented method.展开更多
Osteoarthritis （OA） is a common chronic degenerative joint disease, with complicated pathogenic factors and undefined pathogenesis. Various signaling pathways play important roles in OA pathogenesis, including genet...Osteoarthritis （OA） is a common chronic degenerative joint disease, with complicated pathogenic factors and undefined pathogenesis. Various signaling pathways play important roles in OA pathogenesis, including genetic expression, matrix synthesis and degradation, cell proliferation, differentiation, apoptosis, and so on. MicroRNA （miRNA） is a class of non-coding RNA in Eukaryon, regulating genetic expression on the post-transcriptional level. A great number of miRNAs are involved in the development of OA, and are closely associated with different signaling pathways. This article reviews the roles of miRNAs and signaling pathways in OA, looking toward having a better understanding of its pathogenesis mechanisms and providing new therapeutic targets for its treatment.展开更多
基金Project supported by the National Natural Science Foundation of China(Grant No.61701057)the Chongqing Research Program of Basic Research and Frontier Technology,China(Grant No.cstc2017jcyjAX0345).
文摘We present a time domain hybrid method to realize the fast coupling analysis of transmission lines excited by space electromagnetic fields, in which parallel finite-difference time-domain (FDTD) method, interpolation scheme, and Agrawal model-based transmission line (TL) equations are organically integrated together. Specifically, the Agrawal model is employed to establish the TL equations to describe the coupling effects of space electromagnetic fields on transmission lines. Then, the excitation fields functioning as distribution sources in TL equations are calculated by the parallel FDTD method through using the message passing interface (MPI) library scheme and interpolation scheme. Finally, the TL equations are discretized by the central difference scheme of FDTD and assigned to multiple processors to obtain the transient responses on the terminal loads of these lines. The significant feature of the presented method is embodied in its parallel and synchronous calculations of the space electromagnetic fields and transient responses on the lines. Numerical simulations of ambient wave acting on multi-conductor transmission lines (MTLs), which are located on the PEC ground and in the shielded cavity respectively, are implemented to verify the accuracy and efficiency of the presented method.
基金Project supported by the Ministry of Health of the People’s Republic of China(No.201302007)
文摘Osteoarthritis （OA） is a common chronic degenerative joint disease, with complicated pathogenic factors and undefined pathogenesis. Various signaling pathways play important roles in OA pathogenesis, including genetic expression, matrix synthesis and degradation, cell proliferation, differentiation, apoptosis, and so on. MicroRNA （miRNA） is a class of non-coding RNA in Eukaryon, regulating genetic expression on the post-transcriptional level. A great number of miRNAs are involved in the development of OA, and are closely associated with different signaling pathways. This article reviews the roles of miRNAs and signaling pathways in OA, looking toward having a better understanding of its pathogenesis mechanisms and providing new therapeutic targets for its treatment.
